-
1
-
-
0028075942
-
Mechanism-based pharmacodynamic modeling
-
Levy G. (1994): Mechanism-based pharmacodynamic modeling. Clin. Pharmacol. Ther. 56,256-258.
-
(1994)
Clin. Pharmacol. Ther.
, vol.56
, pp. 256-258
-
-
Levy, G.1
-
2
-
-
0024442139
-
The phenomenon and rational of marked dependence of drug concentration on blood sampling site: Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part I)
-
Chiou W.L. (1989): The phenomenon and rational of marked dependence of drug concentration on blood sampling site: Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part I). Clin. Pharmacokinet. 17, 175-199.
-
(1989)
Clin. Pharmacokinet.
, vol.17
, pp. 175-199
-
-
Chiou, W.L.1
-
3
-
-
0024461323
-
The phenomenon and rational of marked dependence of drug concentration on blood sampling site: Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part II)
-
Chiou W.L. (1989): The phenomenon and rational of marked dependence of drug concentration on blood sampling site: Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part II). Clin. Pharmacokinet. 17, 275-290.
-
(1989)
Clin. Pharmacokinet.
, vol.17
, pp. 275-290
-
-
Chiou, W.L.1
-
4
-
-
0026530191
-
Pharmacokinetic-pharmacodynamic modeling: Time dependent protein binding_an alternative interpretation of clockwise and counterclockwise hysteresis
-
Pedraz J.L., Calvo B., Smithers J.A., Thompson G.A. (1992): Pharmacokinetic-pharmacodynamic modeling: Time dependent protein binding_an alternative interpretation of clockwise and counterclockwise hysteresis. J. Pharm. Sci. 81, 232-236.
-
(1992)
J. Pharm. Sci.
, vol.81
, pp. 232-236
-
-
Pedraz, J.L.1
Calvo, B.2
Smithers, J.A.3
Thompson, G.A.4
-
5
-
-
0026576338
-
Stereochemical considerations in pharmacodynamic modeling of chiral drugs
-
Mehvar R. (1992): Stereochemical considerations in pharmacodynamic modeling of chiral drugs. J. Pharm. Sci. 81, 199-200.
-
(1992)
J. Pharm. Sci.
, vol.81
, pp. 199-200
-
-
Mehvar, R.1
-
6
-
-
0027245597
-
Interpretation and utilization of effect and concentration data collected with an in-vivo pharmacokinetic and in-vitro pharmacodynamic study design
-
Gupta S.K., Hwang S.S., Benet L.Z., Gumbleton M. (1993): Interpretation and utilization of effect and concentration data collected with an in-vivo pharmacokinetic and in-vitro pharmacodynamic study design. Pharm. Res. 10, 889-894.
-
(1993)
Pharm. Res.
, vol.10
, pp. 889-894
-
-
Gupta, S.K.1
Hwang, S.S.2
Benet, L.Z.3
Gumbleton, M.4
-
7
-
-
0019785890
-
Understanding the dose-effect relationship: Clinical application of pharmacokinetic-pharmacodynamic models
-
Holford N.H.G., Sheiner L.B. (1981): Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models. Clin. Pharmacokinet. 6,429-453.
-
(1981)
Clin. Pharmacokinet.
, vol.6
, pp. 429-453
-
-
Holford, N.H.G.1
Sheiner, L.B.2
-
9
-
-
0030175269
-
Fit fluctuating blood drug concentration: A beginner's first note
-
Wu G. (1996): Fit fluctuating blood drug concentration: a beginner's first note. Pharmacol. Res. 33. 379-383.
-
(1996)
Pharmacol. Res.
, vol.33
, pp. 379-383
-
-
Wu, G.1
-
10
-
-
0031172024
-
An explanation for failure to predict cyclosporine area under the curve using a limited sampling strategy: A beginner's second note
-
Wu G. (1997): An explanation for failure to predict cyclosporine area under the curve using a limited sampling strategy: a beginner's second note. Pharmacol. Res. 35, 547-552.
-
(1997)
Pharmacol. Res.
, vol.35
, pp. 547-552
-
-
Wu, G.1
-
11
-
-
0030754570
-
Using a four-compartment closed model to describe inhalation of vaporised ethanol on 1-14C-pyruvate kinetics in mice
-
Wu G. (1997): Using a four-compartment closed model to describe inhalation of vaporised ethanol on 1-14C-pyruvate kinetics in mice. Arch. Toxicol. 71, 501-507.
-
(1997)
Arch. Toxicol.
, vol.71
, pp. 501-507
-
-
Wu, G.1
-
12
-
-
0030815416
-
Use of a five-compartment closed model to describe the effects of ethanol inhalation on the transport and elimination of injected pyruvate in the rat
-
Wu G. (1997): Use of a five-compartment closed model to describe the effects of ethanol inhalation on the transport and elimination of injected pyruvate in the rat. Alcohol. Alcohol. 32,555-561.
-
(1997)
Alcohol. Alcohol.
, vol.32
, pp. 555-561
-
-
Wu, G.1
-
13
-
-
0031940322
-
14C] pyruvate kinetics in mice using a four-compartment closed model
-
14C] pyruvate kinetics in mice using a four-compartment closed model. Pharmacol. Res. 37, 49-55.
-
(1998)
Pharmacol. Res.
, vol.37
, pp. 49-55
-
-
Wu, G.1
-
14
-
-
0031939679
-
Assessment of glomerular filtration rate by means of the three-compartment closed model after a single intravenous injection
-
Wu G. (1998): Assessment of glomerular filtration rate by means of the three-compartment closed model after a single intravenous injection. Arch. Ital. Urol. Androl. 70, 7-10.
-
(1998)
Arch. Ital. Urol. Androl.
, vol.70
, pp. 7-10
-
-
Wu, G.1
-
15
-
-
0032005930
-
Estimation of drug excretion rate from blood into gut using a three-compartment closed model
-
Wu G. (1998): Estimation of drug excretion rate from blood into gut using a three-compartment closed model. Pharmacol. Res. 37, 157-163.
-
(1998)
Pharmacol. Res.
, vol.37
, pp. 157-163
-
-
Wu, G.1
-
16
-
-
0032039235
-
Assessment of glomerular filtration rate by means of the four-, and more compartmental closed models after a single intravenous injection
-
Wu G. (1998): Assessment of glomerular filtration rate by means of the four-, and more compartmental closed models after a single intravenous injection. Arch. Ital. Urol. Androl. 70, 51-55.
-
(1998)
Arch. Ital. Urol. Androl.
, vol.70
, pp. 51-55
-
-
Wu, G.1
-
17
-
-
0032215638
-
Using three-, four- and n-compartment closed model to estimate glomerular filtration rate during and after a constant rate intravenous infusion
-
Wu G. (1998): Using three-, four- and n-compartment closed model to estimate glomerular filtration rate during and after a constant rate intravenous infusion. Eur. J. Pharm. Biopharm. 46, 397-402.
-
(1998)
Eur. J. Pharm. Biopharm.
, vol.46
, pp. 397-402
-
-
Wu, G.1
-
18
-
-
0032885075
-
14C]-pyruvate kinetics in mice using a six-compartment closed model
-
14C]-pyruvate kinetics in mice using a six-compartment closed model. Eur. J. Drug Metab. Pharmacokinet. 24, 113-119.
-
(1999)
Eur. J. Drug Metab. Pharmacokinet.
, vol.24
, pp. 113-119
-
-
Wu, G.1
-
19
-
-
0033840260
-
Sensitivity analysis of pharmacokinetic parameters in one-compartment models
-
Wu G. (2000): Sensitivity analysis of pharmacokinetic parameters in one-compartment models. Pharmacol. Res. 41, 445-453.
-
(2000)
Pharmacol. Res.
, vol.41
, pp. 445-453
-
-
Wu, G.1
-
20
-
-
0034870699
-
Sensitivity analysis of pharmacodynamic parameters in pharmacodynamic models
-
Wu G. (2001): Sensitivity analysis of pharmacodynamic parameters in pharmacodynamic models. Eur. J. Drug Metab. Pharmacokinet. 26, 59-63.
-
(2001)
Eur. J. Drug Metab. Pharmacokinet.
, vol.26
, pp. 59-63
-
-
Wu, G.1
-
21
-
-
0035987070
-
Squared correlation coefficient of measured values versus predicted values in linear and monoexponential regressions
-
Wu G. (2002): Squared correlation coefficient of measured values versus predicted values in linear and monoexponential regressions. Eur. J. Drug Metab. Pharmacokinet 27, 113, o117.
-
(2002)
Eur. J. Drug Metab. Pharmacokinet.
, vol.27
, pp. 113
-
-
Wu, G.1
-
23
-
-
0003963664
-
-
Dover Publications, Inc, New York
-
Tolstov G.P. (1976): Fourier series. Dover Publications, Inc, New York.
-
(1976)
Fourier Series
-
-
Tolstov, G.P.1
-
24
-
-
0003459578
-
-
New York: John Wiley & Sons
-
Carson E.R., Cobelli C., Finkelstein L, (1983): The mathematical modeling of metabolic and endocrine systems: model formulation, identification, and validation. New York: John Wiley & Sons.
-
(1983)
The Mathematical Modeling of Metabolic and Endocrine Systems: Model Formulation, Identification, and Validation
-
-
Carson, E.R.1
Cobelli, C.2
Finkelstein, L.3
-
25
-
-
0014341045
-
Kinetics of interaction between drugs and biological systems
-
Segre G. (1968): Kinetics of interaction between drugs and biological systems. Il Farmaco 23,907-918.
-
(1968)
Il Farmaco
, vol.23
, pp. 907-918
-
-
Segre, G.1
-
33
-
-
0004168384
-
-
Massachusetts: Addison-Wesley
-
Scott R.E. (1960): Linear circuits. Massachusetts: Addison-Wesley.
-
(1960)
Linear Circuits
-
-
Scott, R.E.1
-
35
-
-
85038524571
-
-
Ph.D. Thesis: "The principles of network thermodynamics." Massachusetts: Harvard University
-
Peusner L. (1970): Ph.D. Thesis: "The principles of network thermodynamics." Massachusetts: Harvard University.
-
(1970)
-
-
Peusner, L.1
-
36
-
-
12244274543
-
-
Ph.D. Thesis: "Modelling of pharmacokinetic process using theory of electrical circuit." Moscow: Russian State Medical University (in Russian)
-
Wu G. (1992): Ph.D. Thesis: "Modelling of pharmacokinetic process using theory of electrical circuit." Moscow: Russian State Medical University (in Russian).
-
(1992)
-
-
Wu, G.1
-
37
-
-
0021739344
-
Pharmacokinetic-pharmacodynamic modeling and simulation using the electrical circuit simulation program SPICE2
-
Thakker K.M. (1984): Pharmacokinetic-pharmacodynamic modeling and simulation using the electrical circuit simulation program SPICE2. Biopharm. Drug Dispos. 5, 315-333.
-
(1984)
Biopharm. Drug Dispos.
, vol.5
, pp. 315-333
-
-
Thakker, K.M.1
-
38
-
-
0019513182
-
A network thermodynamic model of glomerular dynamics: Application in the rat
-
Oken D.E., Thomas S.R., Mikulecky D.C. (1981): A network thermodynamic model of glomerular dynamics: application in the rat. Kidney Int. 19, 359-373.
-
(1981)
Kidney Int.
, vol.19
, pp. 359-373
-
-
Oken, D.E.1
Thomas, S.R.2
Mikulecky, D.C.3
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