Effects of oxidizing adulterants on detection of 11-nor-Δ9-THC-9-carboxylic acid in urine

Journal of Analytical Toxicology

Volumn 26, Issue 7, 2002, Pages 460-463

  Paul, Buddha D ^a   Jacobs, Aaron ^a  

^a ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORATE; CHROMIC ACID; FERROUS AMMONIUM SULFATE; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; IODATE; NITRITE; OXIDIZING AGENT; OXYCHLORIDE; PERCHLORATE; PERIODATE; PERMANGANATE; PEROXYSULFURIC ACID; PLANT EXTRACT; SODIUM DITHIONITE; TETRAHYDROCANNABINOLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE STUDY; DRUG DEGRADATION; DRUG DETERMINATION; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; ROOM TEMPERATURE; URINALYSIS;

ARMORACIA RUSTICANA; BRASSICA; BRASSICA NIGRA; CANNABIS SATIVA; RAPHANUS; RAPHANUS SATIVUS; RAPHANUS SATIVUS VAR. NIGER;

EID: 0036825453     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/26.7.460     Document Type: Article

References (15)

1. S.L. Mikkelsen and K.O. Ash. Adulterants causing false negatives in illicit drug testing. Clin. Chem. 34: 2333-2336 (1988).
2. A. Warner. Interference of common household chemicals in immunoassay methods for drugs of abuse. Clin. Chem. 35: 648-651 (1989).
3. J.T. Cody and R.H. Schwarzhoff. Impact of adulterants on RIA analysis of urine for drugs of abuse. J. Anal. Toxicol. 13: 277-284 (1989).
4. W. Broner, P. Nyman, and D. Von Minden. Detectibility of phencyclidine and 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid in adulterated urine by radioimmunoassay and fluorescence polarization immunoassay. J. Anal. Toxicol. 14: 368-371 (1990).
5. R. Schwarzhoff and J.T. Cody. The effects of adulterating agents on FPIA analysis of urine for drugs of abuse. J. Anal. Toxicol. 17: 14-17 (1993).
6. S.-C.J. Tsai, M.A. ElSohly, T. Dubrovsky, B. Twarowska, J. Towt, and S.J. Salamone. Determination of five abused drugs in nitrite-adulterated urine by immunoassays and gas chromatography-mass spectrometry. J. Anal. Toxicol. 22: 474-480 (1998).
7. J.T. Cody and S. Valtier. Effects of Stealth™ adulterant on immunoassay testing for drugs of abuse. J. Anal. Toxicol. 25: 466-470 (2001).
8. A.H.B. Wu, B. Bristol, K. Sexton, G. Cassella-McLane, V. Holtman, and D.W. Hill. Adulteration of urine by "Urine Luck". Clin. Chem. 45: 1051-1057 (1999).
9. C. Baiker, L. Serrano, and B. Lindner. Hypochlorite adulteration of urine causing decreased concentration of delta-9-THC by GC/MS. J. Anal. Toxicol. 18: 101-103 (1994).
10. 9-THC-9-COOH. J. Anal. Toxicol. 21: 240-242 (1997).
11. S.A. Lewis, Sr., L.A. Lewis, and A. Tuinman. Potassium nitrite reaction with 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid in urine in relation to the drug screening analysis. J. Forensic Sci. 44: 951-955 (1999).
12. Department of Health and Human Services, SAMHSA. Guidance for Reporting Specimen Validity Test Results. National Laboratory Certification Program, PD 35, September 28, 1998.
13. Department of Health and Human Services, SAMHSA. Specimen Validity Testing. National Laboratory Certification Program, PD 37, July 28, 1999.
14. B.D. Paul, K.K. Martin, J. Maguilo, and M.L. Smith. Effects of pyridinium chlorochromate adulterant (Urine Luck) on testing drugs of abuse and a method for quantitative detection of chromium (VI) in urine. J. Anal. Toxicol. 24: 233-237 (2000).
15. B.D. Paul, L.D. Mell, J.M. Mitchell, and R.M. McKinley. Detection and quantitation of urinary 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid, a metabolite of tetrahydrocannabinol, by capillary gas chromatography and electron ionization mass spectrometry. J. Anal. Toxicol. 11: 1-5 (1987).