Adjuvant effect of Leishmania major promastigotes on the immune response of mice to ovalbumin

Iranian Biomedical Journal

Volumn 6, Issue 4, 2002, Pages 123-128

  Alimohammadian, Mohammad Hossein ^a   Darabi, Haideh ^a   Kariminia, Amma ^a   Rivier, Denis ^b   Bovay, Philippe ^b   Mauel, Jacques ^b   Ajdary, Soheila ^a   Kharazmi, Arsalan ^c  

^a PASTEUR INSTITUTE OF IRAN   (Iran)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c Rigshospitalet   (Denmark)

Author keywords

Adjuvant; Immune response; L. major; Mice; Ovalbumin

Indexed keywords

BCG VACCINE; FREUND ADJUVANT; INTERFERON; INTERLEUKIN 4; LEISHMANIA VACCINE; OVALBUMIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFECT; FEMALE; IMMUNE RESPONSE; INOCULATION; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPH NODE CELL; LYMPHOCYTE; MOUSE; NONHUMAN; PROMASTIGOTE; T LYMPHOCYTE; TH1 CELL; TREATMENT OUTCOME;

ANIMALIA; CELL FUSING AGENT VIRUS; LEISHMANIA MAJOR; MYCOBACTERIUM BOVIS BCG;

EID: 0036824713     PISSN: 1028852X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Edwards, D. and Kirkpatrick, C.H. (1986) The Immunology of mycobacterial Diseases. Am. Rev. Respir. Dis. 134: 1062-1071.
2. Muller, I., Garcia-Sanz, J.A., Titus, R., Behin, R. and Louis, J. (1989) Analysis of the cellular parameters of the immune responses contributing to resistance and susceptibility of mice to infection with the intracellular parasite, Leishmania major. Immunol. Rev. 112: 95-113.
3. Cooper, A.M. and Flynn, J.L. (1995) The protective immune response to Mycobacterium tuberculosis. Curr. Opin. Immunol. 7: 512-516.
4. Rada, E., Trujillo, D., Castellanos, P.L. and Convit, J. (1987) Gamma interferon production induced by antigens in patients with leprosy and American cutaneous leishmaniasis. Am. J. Trop. Med. Hyg. 37: 520-524.
5. Scott, P. and Kaufmann, S.H.E. (1991) The role of T-cell subsets and cytokines in the regulation of infection. Immunol. Today 12: 346-348.
6. Hughes, H.PA (1988) Oxidative killing of intracellular parasites mediated by macrophages. Parasitol. Today 4: 340-347.
7. Mostafa, A.S., Kvalheim, G., Degr, M. and Godal, T. (1986) Mycobacterium bovis BCG-induced human T-cell clones from BCG-vaccinated healthy subjects: Antigen specificity and lymphokine production. Infect. Immun. 53: 491-497.
8. Melby, P.C. and Sacks, D.L. (1989) Identification of antigens recognized by T cells in human leishmaniasis: Analysis of T-cell clones by immunoblotting. Infect. Immun. 57: 2971-2976.
9. Smrkovski, L.L. and Larson, C.L. (1977) Effect of treatment with BCG on the course of visceral lishmaniasis in BALB/c mice. Infect. Immun. 16: 249-257.
10. Roffi, J., Dedet, J.P., Desjeux, P. and Garre, M.T. (1980) Detection of circulating antibodies in cutaneous leishmaniasis by enzym-linked immunosorbent assay (ELISA). Am. J. Trop. Med Hyg. 29: 183-189.
11. Frommel, D. and Lagrange, P.H. (1989) BCG: A modifier of immune responses to parasites. Parasitol. Today 5: 188-190.
12. Convit, J., Castellanos, P.L., Ulrich, M., Castes, M., Randon, A., Pinardi, M.E., Rodriquez, N., Bloom, B.R., Formica, S., Valecillos, L. and Bretana, A. (1989) Immunotherapy of localized, intermediate, and diffuse forms of American cutaneous leishmaniasis. J. Infect. Dis. 160: 104-115.
13. Bahar, K., Dowlati, Y., Shidani, B., Alimohammadian, M.H., Khamesipour, A., Ehsasi, S., Hashemi-Fesharaki, R., Ale-Agha, S., Modabber, F. (1996) Comparative safety and immunogenicity trial of two killed Leishmania major vaccines with or without BCG in human volunteers. In: Clinics in Dermatology. (Dowlati, Y. & Modabber, F. eds.), Elsevier Science BV, Amsterdam. 14: 489-495.
14. Momeni, A.Z., Jalayer, T., Emamjomeh, M., Khamesipour, A., Zicker, F., Labaf Ghassemi, R., Dowlati, Y., Sharifi, I., Aminjavaheri, M., Shafiei, A., Alimohammadian, M.H., Hashemi-Fesharaki, R., Nasseri, K., Godal, T., Smith, P.G., Modabber, F. (1999) A randomized, double-blind, controlled trial of a killed L. major vaccine plus BCG against zoonotic cutaneous leishmaniasis in Iran. Vaccine 17: 466-472.
15. Sharifi, I., Fekri, A.R., Aflatonian, M.R., Khamesipour, A., Nadim, A., Mousavi, M.R.A., Momeni, A.Z., Dowlati, Y., Godal, T., Zicker, F., Smith, P.G. and Modabber, F. (1998) Randomised vaccine trial of a single dose of killed Leishmania major plus BCG against anthroponotic cutaneous leishmaniasis in Bam, Iran. Lancet 351: 1540-1543.
16. Khalil, E.A.G., El Hassan, A.M., Zijlstra, E.E., Mukhtar, M.M., Ghalib, H.W., Musa, B., Ibrahim, M.E., Kamil, A.A., Elsheikh, M., Babiker, A. and Modabber, F. (2000) Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan. Lancet 356: 1565-1569.
17. Milstien, J.B. and Gibson, J.J. (1990) Quality control of BCG vaccine by WHO: a review of factors that may influence vaccine effectiveness and safety. WHO Bulletin OMS 68: 93-108.
18. Simila, S., Liedes, E. and Kinnunen, P. (1988) Sternal abscess as a complication of BCG-revaccination. Tubercle 69: 67-69.
19. Convit, J., Shoenfeld, Y. and Isenberg, D.A. (1988) Mycobacteria and autoimmunity. Immunol. Today 9: 178-182.
20. Modabber, F. (1995) Vaccines against leishmaniasis. Ann. Trop. Med Parasitol. 89 (Supplement No. 1): 83-88.
21. Virella, G. and Bierer, B.E. (1997) The induction of an immune response: Antigens, lymphocytes and accessory cells. In: Introduction to Medical Immunology (Virella, G. ed.), Marcel Dekker Inc., Basel, pp. 49-73.
22. Loius, J., Moedder, E., Behine, R. and Engers, H. (1979) Recognition of protozoan parasite antigens by murine T lymphocytes. I. Induction of specific T lymphocyte-dependent proliferation response to Leishmania tropica. Eur. J. Immunol. 9: 841-847.
23. Harlow, E. and Lane, D. (1988) Immunoassay. In: Antibodies, a laboratoty manual (Harlow, E. & Lane, D., eds.), Cold Spring Harbor Laboratory, New York, pp. 553-612.
24. Sypek, J.P., Chung, C.L., Mayor, S.E., Subramanyan, J.M., Goldman, S.J., Sieburth, D.S., Wolf, S.F. and Schoub, R.G. (1993) Resolution of cutaneous leishmaniasis: Interleukin 12 initiates a protective T helper type 1 immune response. J. Exp. Med. 177:1797-1802.
25. + cells are different from Th2 cells. Eur. J. Immunol. 20: 2067-2074.
26. Carvalho, E.M., Filho, D.C., Bacellar, O., Almeida, R.P., Lessa, H. and Rocha, H. (1995) Characterization of the immune response in subjects with self-healing cutaneous leishmaniasis. Am. J. Trop. Med. Hyg. 53: 273-277.
27. Kemp, M., Hey, A.S., Kurtzhals, Christensen, C.B., Gaffar, A., Mustafa, M.D., Kordofani, A.A., Ismail, A., Kharazmi, A. and Theander, T.G. (1994) Dichotomy of the human T cell response antigens. I. Th1-like response to Leishmania major promastigote antigen in individuals recovered from cutaneous leishmaniasis. Clin. Exp. Immunol. 96: 410-415.
28. De Luca, P.M., Mayrink, W., Alves, C.R., Coutinho, S.G., Oliveira, M.P., Bertho, A.L., Tolede, V.P., Costa, C.A., Genaro, O. and Mendoca, S.C. (1999) Evaluation of the stability and immunogenicity of autoclaved and non-autoclaved preparations of a vaccine against American tegumentary leishmaniasis. Vaccine 17: 1179-1185.
29. Castes, M., Blackwell, J., Trujillo, D., Formica, S., Cabrera, M., Zorrilla, G., Rodas, A., Castellanos, P.L. and Convit, J. (1994) Immune response in healthy volunteers vaccinated with killed leishmanial promastigotes plus BCG. I: Skin-test reactivity, T-cell proliferation and interferon-γ production. Vaccine 12: 1041-1051.