Spinal interneurones; how can studies in animals contribute to the understanding of spinal interneuronal systems in man?

Brain Research Reviews

Volumn 40, Issue 1-3, 2002, Pages 19-28

  Jankowska, E ^a   Hammar, I ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Exaggerated stretch reflexes; Modulatory actions of monoamines; Spasticity; Spinal interneuronal systems

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; CLONIDINE; TIZANIDINE;

ALPHA NERVE FIBER; CAT; DRUG TARGETING; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; INTERNEURON; MOTOR DYSFUNCTION; MUSCLE SPINDLE AFFERENT NERVE; MUSCLE STRETCHING; MYOTATIC REFLEX; NERVE CELL EXCITABILITY; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; REVIEW; SPASTICITY; SPINAL CORD INJURY; SPINAL CORD NERVE CELL;

ANIMALS; CATS; EFFERENT PATHWAYS; HUMANS; INTERNEURONS; REFLEX; SPINAL CORD; SPINAL CORD INJURIES;

EID: 0036824702     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0173(02)00185-6     Document Type: Review

References (118)

1. Aggelopoulos N.C., Burton M.J., Clarke R.W., Edgley S.A. Characterization of a descending system that enables crossed group II inhibitory reflex pathways in the cat spinal cord. J. Neurosci. 16:1996;723-729.
2. Aggelopoulos N.C., Edgley S.A. Segmental localisation of the relays mediating crossed inhibition of hindlimb motoneurones from group II afferents in the anaesthetized cat spinal cord. Neurosci. Lett. 185:1995;60-64.
3. Anden N.E., Jukes M.G., Lundberg A., Vyklicky L. The effect of DOPA on the spinal cord. 1. Influence on transmission from primary afferents. Acta Physiol. Scand. 67:1966;373-386.
4. Ashby P., Mailis A., Hunter J. The evaluation of 'spasticity'. Can. J. Neurol. Sci. 14:1987;497-500.
5. Aymard C., Chia L., Katz R., Lafitte C., Penicaud A. Reciprocal inhibition between wrist flexors and extensors in man: a new set of interneurones? J. Physiol. (Lond.). 487:(Pt 1):1995;221-235.
6. Aymard C., Decchi B., Katz R., Lafitte C., Penicaud A., Raoul S., Rossi A. Recurrent inhibition between motor nuclei innervating opposing wrist muscles in the human upper limb. J. Physiol. (Lond.). 499:(Pt 1):1997;267-282.
7. Aymard C., Katz R., Lafitte C., Le Bozec S., Penicaud A. Changes in reciprocal and transjoint inhibition induced by muscle fatigue in man. Exp. Brain Res. 106:1995;418-424.
8. Aymard C., Katz R., Lafitte C., Lo E., Penicaud A., Pradat-Diehl P., Raoul S. Presynaptic inhibition and homosynaptic depression: A comparison between lower and upper limbs in normal human subjects and patients with hemiplegia. Brain. 123:2000;1688-1702.
9. Baldissera F., Hultborn H., Illert M. Integration in spinal neuronal systems. Brooks V.B. Handbook of Physiology. the Nervous System. Motor Control. Vol. II:1981;509-595 American Physiological Society, Bethesda, MD.
10. Barbeau H., McCrea D.A., O'Donovan M.J., Rossignol S., Grill W.M., Lemay M.A. Tapping into spinal circuits to restore motor function. Brain Res. Brain Res. Rev. 30:1999;27-51.
11. Belcher G., Ryall R.W., Schaffner R. The differential effects of 5-hydroxytryptamine, noradrenaline and raphe stimulation on nociceptive and nonnociceptive dorsal horn interneurones in the cat. Brain Res. 151:1978;307-321.
12. Bennett D.J., Li Y., Siu M. Plateau potentials in sacrocaudal motoneurons of chronic spinal rats recorded in vitro. J. Neurophysiol. 86:2001;1955-1971.
13. Bennett D.J., Li Y.L., Harvey P.J., Gorassini M. Evidence for plateau potentials in tail motoneurons of awake chronic spinal rats with spasticity. J. Neurophysiol. 86:2001;1972-1982.
14. O. Rémy-Néris, P. Denys, O. Daniel, H. Barbeau, B. Bussel, Effect of intrathecal clonidine on excitation transmitted by interneurones activated by groups I and II afferents in paraplegics, Exp. Brain Res. (2002), in press.
15. Boorman G., Hulliger M., Lee R.G., Tako K., Tanaka R. Reciprocal Ia inhibition in patients with spinal spasticity. Neurosci. Lett. 127:1991;57-60.
16. Bras H., Jankowska E., Noga B., Skoog B. Comparison of effects of various types of NA and 5-HT agonists on transmission from group II muscle afferents in the cat. Eur. J. Neurosci. 2:1990;1029-1039.
17. Burke D., Gracies J.M., Mazevet D., Meunier S., Pierrot Deseilligny E. Convergence of descending and various peripheral inputs onto common propriospinal-like neurones in man. J. Physiol. (Lond.). 449:1992;655-671.
18. Burke R.E. The use of state-dependent modulation of spinal reflexes as a tool to investigate the organization of spinal interneurons. Exp. Brain Res. 128:1999;263-277.
19. Cavallari P., Edgley S.A., Jankowska E. Postsynaptic actions of midlumbar interneurones on motoneurones of hindlimb muscles in the cat. J. Physiol. (Lond.). 389:1987;675-689.
20. Cavallari P., Fournier E., Katz R., Malmgren K., Pierrot-Deseilligny E., Shindo M. Cutaneous facilitation of transmission in Ib reflex pathways in the human upper limb. Exp. Brain Res. 60:1985;197-199.
21. Chaix Y., Marque P., Meunier S., Pierrot Deseilligny E., Simonetta Moreau M. Further evidence for nonmonosynaptic group I excitation of motoneurones in the human lower limb. Exp. Brain Res. 115:1997;35-46.
22. Chartier-Kastler E., Azouvi P., Yakovleff A., Bussel B., Richard F., Denys P. Intrathecal catheter with subcutaneous port for clonidine test bolus injection. A new route and type of treatment for detrusor hyperreflexia in spinal cord-injured patients. Eur. Urol. 37:2000;14-17.
23. Cody F.W., Richardson H.C., MacDermott N., Ferguson I.T. Stretch and vibration reflexes of wrist flexor muscles in spasticity. Brain. 110:1987;433-450.
24. Conway B.A., Hultborn H., Kiehn O., Mintz I. Plateau potentials in α-motoneurones induced by intravenous injection of L-DOPA and clonidine in the spinal cat. J. Physiol. (Lond.). 405:1988;369-384.
25. Corna S., Grasso M., Nardone A., Schieppati M. Selective depression of medium-latency leg and foot muscle responses to stretch by an α 2-agonist in humans. J. Physiol. (Lond.). 484:1995;803-809.
26. Crone C., Hultborn H., Jespersen B., Nielsen J. Reciprocal Ia inhibition between ankle flexors and extensors in man. J. Physiol. (Lond.). 389:1987;163-185.
27. Crone C., Nielsen J., Petersen N., Ballegaard M., Hultborn H. Disynaptic reciprocal inhibition of ankle extensors in spastic patients. Brain. 117:1994;1161-1168.
28. Davies J., Quinlan J.E. Selective inhibition of responses of feline dorsal horn neurones to noxious cutaneous stimuli by tizanidine (DS103-282) and noradrenaline: involvement of α 2-adrenoceptors. Neuroscience. 16:1985;673-682.
29. Delwaide P.J., Pennisi G. Tizanidine and electrophysiologic analysis of spinal control mechanisms in humans with spasticity. Neurology. 44:(Suppl. 9):1994;S21-27.
30. Downes L., Ashby P., Bugaresti J. Reflex effects from Golgi tendon organ (Ib) afferents are unchanged after spinal cord lesions in humans. Neurology. 45:1995;1720-1724.
31. Eccles J.C., Eccles R.M., Lundberg A. Synaptic actions in motoneurones caused by impulses in Golgi tendon afferents. J. Physiol. (Lond.). 138:1957;227-252.
32. Eccles R., Lundberg A. Synaptic actions in motoneurones by afferents which may evoke the flexion reflex. Arch. Ital. Biol. 97:1959;199-221.
33. Edgley S.A., Jankowska E. An interneuronal relay for group I and II muscle afferents in the midlumbar segments of the cat spinal cord. J. Physiol. (Lond.). 389:1987;647-674.
34. Eken T., Hultborn H., Kiehn O. Possible functions of transmitter-controlled plateau potentials in α motoneurones. Prog. Brain Res. 80:1989;257-267.
35. Eriksson J., Olausson B., Jankowska E. Antispastic effects of L-DOPA. Exp. Brain Res. 111:1996;296-304.
36. Faist M., Blahak C., Duysens J., Berger W. Modulation of the biceps femoris tendon jerk reflex during human locomotion. Exp. Brain Res. 125:1999;265-270.
37. Faist M., Dietz V., Pierrot Deseilligny E. Modulation, probably presynaptic in origin, of monosynaptic Ia excitation during human gait. Exp. Brain Res. 109:1996;441-449.
38. Faist M., Mazevet D., Dietz V., Pierrot Deseilligny E. A quantitative assessment of presynaptic inhibition of Ia afferents in spastics. Differences in hemiplegics and paraplegics. Brain. 117:1994;1449-1455.
39. Fournier E., Katz R., Pierrot-Deseilligny E. Descending control of reflex pathways in the production of voluntary isolated movements in man. Brain Res. 288:1983;375-377.
40. Fournier E., Meunier S., Pierrot-Deseilligny E., Shindo M. Evidence for interneuronally mediated Ia excitatory effects to human quadriceps motoneurones. J. Physiol. (Lond.). 377:1986;143-169.
41. Gladden M.H., Matsuzaki H. Static γ-motoneurones couple group Ia and II afferents of single muscle spindles in anaesthetised and decerebrate cats. J. Physiol. (Lond.). 543:2002;273-288.
42. Grey M.J., Ladouceur M., Andersen J.B., Nielsen J.B., Sinkjaer T. Group II muscle afferents probably contribute to the medium latency soleus stretch reflex during walking in humans. J. Physiol. (Lond.). 534:2001;925-933.
43. Hochman S., McCrea D.A. Effects of chronic spinalization on ankle extensor motoneurons. I. Composite monosynaptic Ia EPSPs in four motoneuron pools. J. Neurophysiol. 71:1994;1452-1467.
44. Hochman S., McCrea D.A. Effects of chronic spinalization on ankle extensor motoneurons. II. Motoneuron electrical properties. J. Neurophysiol. 71:1994;1468-1479.
45. Holmqvist B., Lundberg A., Oscarsson D. Supraspinal inhibitory control of transmission to three ascending spinal pathways influenced by the flexion reflex afferents. Arch. Ital. Biol. 98:1961;60-80.
46. Hongo T., Kudo N., Oguni E., Yoshida K. Spatial patterns of reflex evoked by pressure stimulation of the foot pads in cats. J. Physiol. (Lond.). 420:1990;471-487.
47. Hongo T., Lundberg A., Phillips C.G., Thompson R.F. The pattern of monosynaptic Ia-connections to hindlimb motor nuclei in the baboon: a comparison with the cat. Proc. R. Soc. Lond. B. Biol. Sci. 221:1984;261-289.
48. Hongo T., Pettersson L.G. Comments on group II excitation in hindlimb motoneurones in high and low spinal cats. Neurosci. Res. 5:1988;563-566.
49. Hultborn H., Malmsten J. Changes in segmental reflexes following chronic spinal cord hemisection in the cat. I. Increased monosynaptic and polysynaptic ventral root discharges. Acta Physiol. Scand. 119:1983;405-422.
50. Hultborn H., Malmsten J. Changes in segmental reflexes following chronic spinal cord hemisection in the cat. II. Conditioned monosynaptic test reflexes. Acta Physiol. Scand. 119:1983;423-433.
51. Hultborn H., Meunier S., Morin C., Pierrot Deseilligny E. Assessing changes in presynaptic inhibition of I a fibres: a study in man and the cat. J. Physiol. (Lond.). 389:1987;729-756.
52. Hultborn H., Meunier S., Pierrot Deseilligny E., Shindo M. Changes in presynaptic inhibition of Ia fibres at the onset of voluntary contraction in man. J. Physiol. (Lond.). 389:1987;757-772.
53. Hultborn H., Nielsen J.B. Comments: methodological problems of comparing F responses and H reflexes. Muscle Nerve. 19:1996;1347-1348.
54. Iles J.F. Evidence for cutaneous and corticospinal modulation of presynaptic inhibition of Ia afferents from the human lower limb. J. Physiol. (Lond.). 491:1996;197-207.
55. Iles J.F., Ali A., Pardoe J. Task-related changes of transmission in the pathway of heteronymous spinal recurrent inhibition from soleus to quadriceps motor neurones in man. Brain. 123:2000;2264-2272.
56. Iles J.F., Pisini J.V. Cortical modulation of transmission in spinal reflex pathways of man. J. Physiol. (Lond.). 455:1992;425-446.
57. Iles J.F., Roberts R.C. Inhibition of monosynaptic reflexes in the human lower limb. J. Physiol. (Lond.). 385:1987;69-87.
58. Iles J.F., Roberts R.C. Presynaptic inhibition of monosynaptic reflexes in the lower limbs of subjects with upper motoneuron disease. J. Neurol. Neurosurg. Psychiatry. 49:1986;937-944.
59. Jankowska E. Interneuronal relay in spinal pathways from proprioceptors. Prog. Neurobiol. 38:1992;335-378.
60. Jankowska E. Monoaminergic inhibitory control of spinal interneurons. Thilmann A., Burke D., Rymer Z. Spasticity: Mechanisms and Management. 1993;222-232 Springer, Berlin.
61. Jankowska E., Hammar I., Chojnicka B., Heden C.H. Effects of monoamines on interneurons in four spinal reflex pathways from group I and/or group II muscle afferents. Eur. J. Neurosci. 12:2000;701-714.
62. Jankowska E., Slawinska U., Hammar I. On organization of a neuronal network in pathways from group II muscle afferents in feline lumbar spinal segments. J. Physiol. (Lond.). 542:2002;301-314.
63. Katz L.C. Coordinate activity in retinal and cortical development. Curr. Opin. Neurobiol. 3:1993;93-99.
64. Katz R. Presynaptic inhibition in humans: a comparison between normal and spastic patients. J. Physiol. (Paris). 93:1999;379-385.
65. Katz R., Penicaud A., Rossi A. Reciprocal Ia inhibition between elbow flexors and extensors in the human. J. Physiol. (Lond.). 437:1991;269-286.
66. Katz R., Pierrot-Deseilligny E. Recurrent inhibition of α-motoneurons in patients with upper motor neuron lesions. Brain. 105:1982;103-124.
67. Kitazawa S., Ohki Y., Sasaki M., Xi M., Hongo T. Candidate premotor neurones of skin reflex pathways to T1 forelimb motoneurones of the cat. Exp. Brain Res. 95:1993;291-307.
68. Lundberg A. Descending control of forelimb movements in the cat. Brain Res. Bull. 50:1999;323-324.
69. Lundberg A. Inhibitory control from the brain stem of transmission from primary afferents to motoneurones, primary afferent terminals and ascending pathways. Sjölund B., Björklund A. Brain Stem Control of Spinal Mechanisms. 1982;179-225 Elsevier, Amsterdam.
70. Lundberg A., Malmgren K., Schomburg E.D. Reflex pathways from group II muscle afferents. 1. Distribution and linkage of reflex actions to α-motoneurones. Exp. Brain Res. 65:1987;271-281.
71. Lundberg A., Malmgren K., Schomburg E.D. Reflex pathways from group II muscle afferents. 3. Secondary spindle afferents and the FRA: a new hypothesis. Exp. Brain Res. 65:1987;294-306.
72. Malmgren K., Pierrot-Deseilligny E. Evidence for nonmonosynaptic Ia excitation of human wrist flexor motoneurones, possibly via propriospinal neurones. J. Physiol. (Lond.). 405:1988;747-764.
73. Malmgren K., Pierrot-Deseilligny E. Inhibition of neurones transmitting nonmonosynaptic Ia excitation to human wrist flexor motoneurones. J. Physiol. (Lond.). 405:1988;765-783.
74. Marchand-Pauvert V., Simonetta-Moreau M., Pierrot-Deseilligny E. Cortical control of spinal pathways mediating group II excitation to human thigh motoneurones. J. Physiol. (Lond.). 517:1999;301-313.
75. Marque P., Pierrot Deseilligny E., Simonetta Moreau M. Evidence for excitation of the human lower limb motoneurones by group II muscle afferents. Exp. Brain Res. 109:1996;357-360.
76. Marque P., Simonetta-Moreau M., Maupas E., Roques C.F. Facilitation of transmission in heteronymous group II pathways in spastic hemiplegic patients. J. Neurol. Neurosurg. Psychiatry. 70:2001;36-42.
77. Matthews P.B. The human stretch reflex and the motor cortex. Trends Neurosci. 14:1991;87-91.
78. Mazzocchio R., Rossi A. Involvement of spinal recurrent inhibition in spasticity. Further insight into the regulation of Renshaw cell activity. Brain. 120:1997;991-1003.
79. Mazzocchio R., Rossi A. Recurrent inhibition in human spinal spasticity. Ital. J. Neurol. Sci. 10:1989;337-347.
80. McCrea D.A., Shefchyk S.J., Stephens M.J., Pearson K.G. Disynaptic group I excitation of synergist ankle extensor motoneurones during fictive locomotion in the cat. J. Physiol. (Lond.). 487:1995;527-539.
81. Meunier S., Pierrot Deseilligny E., Simonetta M. Pattern of monosynaptic heteronymous Ia connections in the human lower limb. Exp. Brain Res. 96:1993;534-544.
82. Morin C., Pierrot Deseilligny E., Hultborn H. Evidence for presynaptic inhibition of muscle spindle Ia afferents in man. Neurosci. Lett. 44:1984;137-142.
83. Morita H., Crone C., Christenhuis D., Petersen N.T., Nielsen J.B. Modulation of presynaptic inhibition and disynaptic reciprocal Ia inhibition during voluntary movement in spasticity. Brain. 124:2001;826-837.
84. Nakashima K., Rothwell J.C., Day B.L., Thompson P.D., Shannon K., Marsden C.D. Reciprocal inhibition between forearm muscles in patients with writer's cramp and other occupational cramps, symptomatic hemidystonia and hemiparesis due to stroke. Brain. 112:1989;681-697.
85. Nance P.W. A comparison of clonidine, cyproheptadine and baclofen in spastic spinal cord injured patients. J. Am. Paraplegia Soc. 17:1994;150-156.
86. Nance P.W., Shears A.H., Nance D.M. Clonidine in spinal cord injury. Can. Med. Assoc. J. 133:1985;41-42.
87. Nicolas G., Marchand-Pauvert V., Burke D., Pierrot-Deseilligny E. Corticospinal excitation of presumed cervical propriospinal neurones and its reversal to inhibition in humans. J. Physiol. (Lond.). 533:2001;903-919.
88. Nielsen J., Petersen N., Crone C. Changes in transmission across synapses of Ia afferents in spastic patients. Brain. 118:1995;995-1004.
89. Nielsen J., Pierrot Deseilligny E. Pattern of cutaneous inhibition of the propriospinal-like excitation to human upper limb motoneurones. J. Physiol. (Lond.). 434:1991;169-182.
90. Noth J. Trends in the pathophysiology and pharmacotherapy of spasticity [editorial]. J. Neurol. 238:1991;131-139.
91. Pauvert V., Pierrot-Deseilligny E., Rothwell J.C. Role of spinal premotoneurones in mediating corticospinal input to forearm motoneurones in man. J. Physiol. (Lond.). 508:1998;301-312.
92. Pierrot Deseilligny E. Assessing changes in presynaptic inhibition of Ia afferents during movement in humans. J. Neurosci. Methods. 74:1997;189-199.
93. Pierrot Deseilligny E. Electrophysiological assessment of the spinal mechanisms underlying spasticity. Electroencephalogr. Clin. Neurophysiol. Suppl. 41:1990;264-273.
94. Pierrot Deseilligny E. Transmission of the cortical command for human voluntary movement through cervical propriospinal premotoneurons. Prog. Neurobiol. 48:1996;489-517.
95. Pierrot-Deseilligny E. Peripheral and descending control of neurones mediating nonmonosynaptic Ia excitation to motoneurones: a presumed propriospinal system in man. Prog. Brain Res. 80:1989;305-314. discussion 295-307.
96. Pierrot-Deseilligny E., Bergego C., Katz R. Reversal in cutaneous of Ib pathways during human voluntary contraction. Brain Res. 233:1982;400-403.
97. Pierrot-Deseilligny E., Morin C., Bergego C., Tankov N. Pattern of group I fibre projections from ankle flexor and extensor muscles in man. Exp. Brain Res. 42:1981;337-350.
98. Pierrot-Deseilligny E., Pradat-Diehl P., Robain G. Physiopathology of spasticity. Ann. Readaptation Med. Physicother. 36:1993;309-320.
99. Raynor E.M., Shefner J.M. Recurrent inhibition is decreased in patients with amyotrophic lateral sclerosis. Neurology. 44:1994;2148-2153.
100. Remy-Neris O., Barbeau H., Daniel O., Boiteau F., Bussel B. Effects of intrathecal clonidine injection on spinal reflexes and human locomotion in incomplete paraplegic subjects. Exp. Brain Res. 129:1999;433-440.
101. Rossignol S. Neural control of stereotypic limb movements. Rowell L.B., Sheperd J.T. Exercise: Regulation and Integration of Multiple Systems. 1996;173-216 American Physiological Society, New York.
102. Rossignol S., Gauthier L. An analysis of mechanisms controlling the reversal of crossed spinal reflexes. Brain Res. 182:1980;31-45.
103. Rudomin P., Schmidt R.F. Presynaptic inhibition in the vertebrate spinal cord revisited. Exp. Brain Res. 129:1999;1-37.
104. Schieppati M., Gritti I., Romano C. Recurrent and reciprocal inhibition of the human monosynaptic reflex shows opposite changes following intravenous administration of acetylcarnitine. Acta Physiol. Scand. 143:1991;27-32.
105. Schieppati M., Nardone A. Group II spindle afferent fibers in humans: their possible role in the reflex control of stance. Prog. Brain Res. 123:1999;461-472.
106. Schieppati M., Nardone A. Medium-latency stretch reflexes of foot and leg muscles analysed by cooling the lower limb in standing humans. J. Physiol. (Lond.). 503:1997;691-698.
107. Schieppati M., Romano C., Gritti I. Convergence of Ia fibres from synergistic and antagonistic muscles onto interneurones inhibitory to soleus in humans. J. Physiol. (Lond.). 431:1990;365-377.
108. Shindo M., Harayama H., Kondo K., Yanagisawa N., Tanaka R. Changes in reciprocal Ia inhibition during voluntary contraction in man. Exp. Brain Res. 53:1984;400-408.
109. Simonetta-Moreau M., Marque P., Marchand-Pauvert V., Pierrot-Deseilligny E. The pattern of excitation of human lower limb motoneurones by probable group II muscle afferents. J. Physiol. (Lond.). 517:1999;287-300.
110. Stein P.S., Victor J.C., Field E.C., Currie S.N. Bilateral control of hindlimb scratching in the spinal turtle: contralateral spinal circuitry contributes to the normal ipsilateral motor pattern of fictive rostral scratching. J. Neurosci. 15:1995;4343-4355.
111. Stein R.B., Yang J.F., Belanger M., Pearson K.G. Modification of reflexes in normal and abnormal movements. Prog. Brain Res. 97:1993;189-196.
112. Tanaka R. Reciprocal Ia inhibition and voluntary movements in man. Prog. Brain Res. 44:1976;291-302.
113. Tanaka R. Reciprocal Ia inhibition during voluntary movements in man. Exp. Brain Res. 21:1974;529-540.
114. Taylor J.S., Friedman R.F., Munson J.B., Vierck Jr C.J. Stretch hyperreflexia of triceps surae muscles in the conscious cat after dorsolateral spinal lesions. J. Neurosci. 17:1997;5004-5015.
115. Thilmann A.F., Burke D.J., Rymer W.Z.E. Spasticity: Mechanisms and Management. 1993;46 Springer, Berlin.
116. Wilson V.J., Kato M. Excitation of extensor motoneurons by group II afferent fibers in ipsilateral muscle nerves. J. Neurophysiol. 28:1965;545-554.
117. N. Yanagisawa, R. Tanaka, Reciprocal Ia inhibition in spastic paralysis in man, Electroencephalogr. Clin. Neurophysiol. Suppl. (1978) 521-526.
118. Young R.R. Spasticity: a review. Neurology. 44:1994;S12-20.