Condensed naphtho[1,8-de][1,3]thiazines 1. Synthesis of naphtho[1,8-de][1,2,4]triazolo[3,4-b][1,3]thiazine derivatives and their inhibitory activity on human platelet aggregation

Chinese Pharmaceutical Journal

Volumn 54, Issue 5, 2002, Pages 331-352

  Hsu, Wen Chuan ^a   Tao, Tung Mei ^a   Chou, Tz Chong ^a   Ding, Yu An ^b   Liu, Kang Chien ^a  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

1,3,4 Thiadiazolo 2, 3, b quinazolines; Antihypertensives; Bioluminescence method; Inhibitors of platelet aggregation; Naphtho 1,8 de 1,2,4 triazolo 3,4 b 1,3 thiazines; Pseudothiourea pharmacophore; Thiosemicarbazide pharmacophore; Turbidimetry

Indexed keywords

ADENOSINETRIPHOSPHATE; CONDENSATION; CYTOLOGY; REACTION KINETICS; SYNTHESIS (CHEMICAL);

PLATELETS;

DRUG PRODUCTS;

10 CHLOROMETHYLNAPHTHO[1,8 DE][1,2,4]TRIAZOLO[3,4 B][1,3]THIAZINE; 10 ETHYLNAPHTHO[1,8 DE][1,2,4]TRIAZOLO[3,4 B][1,3]THIAZINE; 10 HYDROXYNAPHTHO[1,8 DE][1,2,4]TIRAZOLO[3,4 B][1,3]THIAZINE; 10 MERCAPTONAPHTHO[1,8 DE][1,2,4]TRIAZOLO[3,4 B][1,3]THIAZINE; 10 METHYLNAPHTHO[1,8 DE][1,2,4]TRIAZOLO[3,4 B][1,3]THIAZINE; 10 PHENYLNAPHTHO[1,8 DE][1,2,4]TRIAZOLO][3,4 B][1,3]THIAZINE; 10 TRIFLUOROMETHYLNAPHTHO[1,3 DE][1,2,4]TRIAZOLO[3,4 B][1,3]THIAZINE; ACID ANHYDRIDE; ADENOSINE DIPHOSPHATE; ADRENALIN; ALUMINUM DERIVATIVE; ALUMINUM LITHIUM HYDRIDE; ANTITHROMBOCYTIC AGENT; ARACHIDONIC ACID; CALCIMYCIN; CARBOXYLIC ACID DERIVATIVE; CHLORIDE; COLLAGEN; HETEROCYCLIC COMPOUND; LITHIUM DERIVATIVE; NAPHTHALENE DERIVATIVE; NAPHTHO[1,3 DE][1,2,4]TRIAZOLO[3,4 B][1,3]THIAZINE DERIVATIVE; NAPHTHO[1,8 DE][1,24]TRIAZOLO[3,4 B][1,3]THIAZINE; NAPHTHO[1,8 DE][1,3]THIAZINE; PHOSPHORUS DERIVATIVE; PHOSPHORUS OXYCHLORIDE; REAGENT; THIAZINE DERIVATIVE; THROMBIN; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CYCLIZATION; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSFORMATION; FLUOROMETRY; HUMAN; HUMAN CELL; PHARMACOPHORE; POLYMERIZATION; REACTION ANALYSIS; REDUCTION; STRUCTURE ANALYSIS; THROMBOCYTE AGGREGATION INHIBITION; TURBIDIMETRY;

EID: 0036824541     PISSN: 10161015     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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