Anti-nociceptive effect of the fruit essential oil of Cuminum cyminum L. in rat

Iranian Biomedical Journal

Volumn 6, Issue 4, 2002, Pages 141-145

  Sayyah, Mohammad ^a   Peirovi, Afshin ^a   Kamalinejad, Mohammad ^b  

^a PASTEUR INSTITUTE OF IRAN   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Anti nociceptive effect; Cuminum cyminum Linn; Essential oil

Indexed keywords

CUMINUM CYMINUM EXTRACT; ESSENTIAL OIL; FORMALDEHYDE; PIROXICAM; PLANT EXTRACT; POLYSORBATE 80; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; CUMIN; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; DRUG TOXICITY; FRUIT; INFLAMMATION; LD 50; MALE; MOUSE; NOCICEPTION; NONHUMAN; PAIN; TAIL FLICK TEST;

ANIMALIA; APIACEAE; CUMINUM CYMINUM;

EID: 0036824318     PISSN: 1028852X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Zargari, A. (1989) Medicinal plants. Vol. II. Tehran University Press, Tehran, pp. 519-521.
2. Willatgamuwa, S.A., Platel, K., Sarawathi, G. and Srinivasan, K. (1998) Anti-diabetic influence of dietary cumin seeds (Cuminum cyminum) in streptozocin induced diabetic rats. Nut. Res. 18: 131-142.
3. Malini, T. and Vanithakumari, G. (1987) Estrogenic activity of Cuminum cyminum in rats. Indian. J Exp. Biol. 5: 442-444.
4. Sayyah, M., Mahboubi, A. and Kamalinejad, M. (2002) Anticonvulsant effect of the fruit essential oil of Cuminum cyminum in mice. Pharm. Biol. 40 (6): 478-480.
5. Tremont-Lukats, I.W., Megeff, C. and Backonja, M.M. (2000) Anticonvulsants for neuropathic pain syndromes: mechanisms of action and place in therapy. Drugs 60: 1029-1052.
6. Srivastava, K.C. (1989) Extracts from two frequently consumed spices cumin (Cuminum cyminum) and turmeric (Curcuma longa) inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets. Prostaglandins Leukotriens Essential Fatty Acids 37: 57-64.
7. Borges, P. and Pino, J. (1993) The isolation of volatile oil from cumin seeds by steam distillation. Die. Nahrung. 2: 123-126
8. Lorente, I., Ocete, M.A., Zarzuelo, A., Cabo, M. and Jimenez, J. (1989) Bioactivity of the essential oil of Bupleurum fruticosum. J. Nat. Prod. 52: 267-272.
9. Lorenzetti, B.B., Souza, G.E., Sarti, S.J., Santos Filho, D. and Ferreira, S.H. (1991) Myrcene mimics the peripheral analgesic activity of lemongrass tea. J. Ethnopharmacol. 34: 43-48.
10. Duarte, I.D., Dos Santos, I.R., Lorenzetti, B.B. and Ferreira, S.H. (1992) Analgesia by direct antagonism of nociceptor sensitization involves the argininenitric oxide-cGMP pathway. Eur. J. Pharmacol. 217: 225-227.
11. D'Amour, F.G. and Smith, D.L. (1941) A method for determining loss of pain sensation. J Pharmacol. Exp. Ther. 72: 74-79.
12. Dubuisson, D. and Dennis, S.G. (1977) The formalin test: A quantitative study of the analgesic effects of morphine, meperidine and brain stem stimulation in rats and cats. Pain 4: 161-174.
13. Litchfield, S.T. and Wilcoxon, F. (1949) A simplified method of evaluating dose-effect experiments. J Pharmacol. Exp. Ther. 96: 99-105.
14. Chau, T. (1989) Pharmacology methods in the control of inflammation. In: Modern methods in pharmacology. Vol. IV. Alan R Liss Inc., New York, pp. 195-212.
15. Tjølsen, A., Berge, O.G., Hunskaar, S., Rosland, J.H. and Hole, K. (1992) The formalin test: an evaluation of the method. Pain 51: 5-17.
16. Shibata, M., Ohkubo, T., Takahashi, H. and Inoki, R. (1989) Modified formalin test: characteristic biphasic pain response. Pain 38: 347-352.
17. Chapman, V. and Dickenson, A.H. (1992) The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the rat. Eur. J. Pharmacol. 219: 427-733.
18. Malmberg, A.B. and Yaksh, T.L. (1995) Cyclooxygenase inhibition and the spinal release of prostaglandin E2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats. J. Neurosci. 15: 2768-2776.
19. Doak, G.L. and Sawynok, J. (1997) Formalin-induced nociceptive behavior and edema: involvement of multiple peripheral 5-hydroxytryptamine receptor subtypes. Neuroscience 80: 939-949.