Evidence for linkage of HLA loci in juvenile idiopathic oligoarthritis: Independent effects of HLA-A and HLA-DRB1

Arthritis and Rheumatism

Volumn 46, Issue 10, 2002, Pages 2716-2720

  Zeggini, Eleftheria ^a,b   Donn, Rachelle P ^a   Ollier, William E R ^a   Thomson, Wendy ^a   Abinun, M ^c   Becker, M ^c   Bell, A ^c   Craft, A ^c   Crawley, E ^c   David, J ^c   Foster, H ^c   Gardener Medwin, J ^c   Griffin, J ^c   Hall, A ^c   Hall, M ^c   Herrick, A ^c   Hollingworth, P ^c   Holt, L ^c   Jones, S ^c   Pountain, G ^c   Ryder, C ^c   Southwood, T ^c   Stewart, I ^c   Woo, P ^c   Wyatt, S ^c   Venning, H ^c   more..

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b ARC/EU   (United Kingdom)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; HLA DR ANTIGEN;

ADULT; ALLELE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA MODIFICATION; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HLA SYSTEM; HUMAN; INTERNATIONAL COOPERATION; JUVENILE RHEUMATOID ARTHRITIS; MAJOR CLINICAL STUDY; MALE; OLIGONUCLEOTIDE PROBE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ALLELES; ARTHRITIS, JUVENILE RHEUMATOID; CHILD; CHILD, PRESCHOOL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HLA-A ANTIGENS; HLA-B ANTIGENS; HLA-DR ANTIGENS; HUMANS; INFANT; LINKAGE (GENETICS); MALE;

EID: 0036822547     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10551     Document Type: Article

References (19)

1. Glass DN, Giannini EH. Juvenile rheumatoid arthritis as a complex genetic trait. Arthritis Rheum 1999;42:2261-8.
2. Savolainen A, Saila H, Kotaniemi K, Kaipiainen-Seppanen O, Leirisalo-Repo M, Aho K. Magnitude of the genetic component injuvenile idiopathic arthritis. Ann Rheum Dis 2000;59:1001.
3. Brewer EJ Jr, Bass JC, Baum J, Cassidy JT, Fink C, Jacobs J, et al. Current proposed revision of JRA criteria. Arthritis Rheum 1977;20 Suppl 2:195-9.
4. Wood PHN. Nomenclature and classification of arthritis in children. In: Munthie E, editor. The care of rheumatic children. Basel: EULAR Publishers; 1978. p. 47.
5. Petty RE, Southwood TR, Baum J, Bhettay E, Glass DN, Manners P, et al. Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol 1998;25:1991-4.
6. Donn RP, Ollier WER. Juvenile chronic arthritis: a time for change? Eur J Immunogenet 1996;23:245-60.
7. Albert ED, Scholz S. Juvenile arthritis: genetic update. Baillieres Clin Rheumatol 1998;12:209-18.
8. Prahalad S, Ryan MH, Shear ES, Thompson SD, Giannini EH, Glass DN. Juvenile rheumatoid arthritis: linkage to HLA demonstrated by allele sharing in affected sibpairs. Arthritis Rheum 2000;43:2335-8.
9. Oen K, Petty RE, Schroeder ML. An association between HLA-A2 and juvenile rheumatoid arthritis in girls. J Rheumatol 1982;9:916-20.
10. Daly AK, Day CP. Candidate gene case-control association studies: advantages and potential pitfalls. Br J Clin Pharmacol 2001;52:489-99.
11. Moroldo MB, Donnelly P, Saunders J, Glass DN, Giannini EH. Transmission disequilibrium, as a test of linkage and association between HLA alleles and pauciarticular-onset juvenile rheumatoid arthritis. Arthritis Rheum 1998;40:1620-4.
12. Carrington M. Recombination within the human MHC. Immunol Rev 1999;167:245-56.
13. Morison IM, Paton CJ, Cleverley SD. The imprinted gene and parent-of-origin effect database. Nucleic Acids Res 2001;29:275-6.
14. Sasaki T, Nemoto M, Yamasaki K, Tajima N. Preferential transmission of maternal allele with DQA1*0301-DQB1*0302 haplotype to affected offspring in families with type 1 diabetes. J Hum Genet 1999;44:318-22.
15. Sham PC, Curtis D. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann Hum Genet 1995;59:323-6.
16. Koeleman BP, Dudbridge F, Cordell HJ, Todd JA. Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the conditional extended transmission/disequilibrium test. Ann Hum Genet 2000;64:207-13.
17. Curtis D, Sham PC. Model-free linkage analysis using likelihoods. Am J Hum Genet 1995;57:703-16.
18. Ota M, Katsuyama Y, Kimura A, Tsuchiya K, Kondo M, Naruse T, et al. A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region. Genomics 2001;71:263-70.
19. Feder JN, Gnirke A, Thomas W, Tsuchihashi Z, Ruddy DA, Basava A, et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996;13:399-408.