Can self application of zinc sulphate and usnic acid cream improve the outcome of vulvoperineal HPV infection?

Gazzetta Medica Italiana Archivio per le Scienze Mediche

Volumn 161, Issue 4-5, 2002, Pages 177-181

  Mancino, P ^a   Roma, B ^a   Melluso, J ^a   Onorati, E ^a   Russo, P ^a   Monti, M ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Urogenital diseases, therapy; Usnic acid; Zinc

Indexed keywords

USNIC ACID; ZINC SULFATE;

ADULT; ARTICLE; COLPOSCOPY; CONVALESCENCE; CREAM; CYTOLOGY; DRUG EFFICACY; DRUG SELF ADMINISTRATION; FEMALE; FOLLOW UP; HISTOLOGY; HUMAN; MAJOR CLINICAL STUDY; PERINEUM; TOPICAL TREATMENT; TREATMENT OUTCOME; VIRUS INFECTION; VULVITIS; WART VIRUS;

EID: 0036820119     PISSN: 03933660     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Scirpa P, Scambia G, Masciullo V, Battaglia F, Foti E, Lopez R et al. Terapia adiuvante con un preparato a base di zinco solfato e acido usnico delle lesioni genitali da Human Papilloma Virus (HPV) dopo trattamento chirurgico distruttivo. Minerva Ginecol 1999;51:255-60.
2. Scarpellini M, Fulgenzi P, Papallo R, Tononi A, Monti F, Ravaioli A. Il ruolo della colposcopia nella diagnosi dell'infezione virale da HPV. Minerva Ginecol 1992;44:617-22.
3. Baldoni A, Gonnellini S, Gilardi G. Utilizzo vaginale di un preparato a base di zinco solfato e acido usnico nelle infezioni da HPV cervicale associate e non a displasia lieve. Atti del LXXV Congresso della Società Italiana di Ginecologia e Ostetricia 20-24 giugno 1999; Viareggio; Italia. Roma: CIC Edizioni Internazionali; 1999.p.592-6.
4. Carson LF, Twiggs LB, Fukushima M, Ostrow RS, Faras AJ, Okagaki T. Human genital papilloma infections: an evaluation of immunologic competence in the genital neoplasie syndrome. Am J Obstet Gynecol 1986;155:784-8.
5. Benedetti Panici P, Maneschi F, Cutillo G. Lesioni preneoplastiche della cervice uterina. Oncologia 1997;1:18-24.
6. Varadinova TL, Bontchev PR, Nachev CK, Shishkov SA, Strachilov D, Paskalev Z et al. Mode of action of Zn-complexes on herpes simplex virus type 1 infection in vitro. J Chemother 1993;5:3-9.
7. Patrick O, Tennican GZ. The diverse effects of topical and systemic administration of zinc on the virulence of Herpes Simplex Genitalis. Life Sci 1979;24:1877-84.
8. Cardarelli M, Serino G, Campanella L, Ercole P, De Cicco Nardone F, Alesiani O et al. Antimitotic effects of usnic acid on different biological systems. Cell Mol Life Sci 1997;53:67-672.
9. Baginski B. Alterations of the oxidative metabolism and other microbicidal activities of human polymorphonuclear leukocytes by zinc. Free Radic Res Commun 1990;10:227-35.
10. Steffensen IL, Mesua OJ, Melhuus A. Mitogenicity and metallothionein induction: two separate effects of zinc ions on human mononuclear blood cells. Gynecol Toxicol 1991;69:445-9.