Treatment of sexual disorders in people with epilepsy

Epilepsy and Behavior

Volumn 3, Issue 5 SUPPL. 1, 2002, Pages 38-41

  Harden, Cynthia L ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Dehydroepiandrosterone; Sexual disorder; Sexual dysfunction; Sildenafil; Testosterone

Indexed keywords

ANTICONVULSIVE AGENT; BARBITURIC ACID DERIVATIVE; CARBAMAZEPINE; CYTOCHROME P450 INHIBITOR; ETIRACETAM; GABAPENTIN; GONADOTROPIN; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PRASTERONE; PRIMIDONE; SEDATIVE AGENT; SEX HORMONE BINDING GLOBULIN; SILDENAFIL; TESTOSTERONE; TIAGABINE; TOPIRAMATE; VALPROIC ACID; ZONISAMIDE;

ANORGASMIA; BRAIN FUNCTION; DRUG CLEARANCE; DRUG EFFICACY; DRUG INFORMATION; DRUG METABOLISM; EPILEPSY; FEMALE; GONADOTROPIN RELEASE; HEALTH SURVEY; HORMONE DETERMINATION; HORMONE SUBSTITUTION; HUMAN; MALE; PATHOPHYSIOLOGY; RATING SCALE; REVIEW; RISK FACTOR; SELF REPORT; SEXOLOGY; SEXUAL BEHAVIOR; SEXUAL DYSFUNCTION; SEXUAL FUNCTION; TESTOSTERONE METABOLISM;

EID: 0036816465     PISSN: 15255050     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1525-5069(02)00504-2     Document Type: Review

References (35)

1. Demerdash A, Shaalan M, Midani A, Kamel F, Bahri M. Sexual behavior of a sample of females with epilepsy. Epilepsia 1991;31:82-5.
2. Taylor DC. Appetitive inadequacy in the sex behavior of temporal lobe epilepsy. J Neurovisc Relat 1971:486-90.
3. Hierons R, Saunders M. Impotence in a patient with temporal lobe lesions. Lancet 1966;2:761-4.
4. Fenwick PB, Toone BK, Wheeler MJ, Nanjee MN, Grant R, Brown D. Sexual behavior in a centre for epilepsy. Acta Neurol Scand 1985;71:28-35.
5. Jensen P, Jensen SB, Sorensen PS, et al. Sexual dysfunction in male and female patients with epilepsy: a study of 86 outpatients. Arch Sex Behav 1990;19:1-14.
6. Deckers CLP, Hekster YA, Keyser A, Lammers MW, Meinardi H, Renier WO. Adverse effects in epilepsy therapy. Wait and see or go for it? Acta Neurol Scand 1997;95:248-52.
7. Fenwick PB, Mercer S, Grant R, et al. Nocturnal penile tumescence and serum testosterone levels. Arch Sex Behav 1986;15:13-21.
8. Guldner GT, Morrell MJ. Nocturnal penile tumescence and rigidity evaluation in men with epilepsy. Epilepsia 1996;37:1211-4.
9. Morrell MJ, Sperling MR, Stecker M, Dichter MA. Sexual dysfunction in partial epilepsy: a deficit in physiologic sexual arousal. Neurology 1994;44:243-7.
10. Rattya J, Rakarinen AJ, Knip M, Repo-Outakoski M, Myllyla VV, Isojarvi JIT. Early hormonal changes during valproate or carbamazepine treatment: a 3-month study. Neurology 2001;57: 440-4.
11. Isojarvi JI, Pakarinen AJ, Ylipalosaari PJ, Myllyla VV. Serum hormones in male epileptic patients receiving anticonvulsant medication. Arch Neurol 1990;47:670-6.
12. Rattya J, Turkka J, Pakarinen AJ, et al. Reproductive effects of valproate, carbamazepine, and oxcarbazepine in men with epilepsy. Neurology 2001;56:31-6.
13. Isojarvi JI, Repo M, Pakarinen AJ, Lukkarinen O, Myllyla VV. Carbamazepine, phenytoin, sex hormones, and sexual function in men with epilepsy. Epilepsia 1995;36:366-70.
14. Herzog AG. Reproductive endocrine considerations and hormonal therapy for men with epilepsy. Epilepsia 1991;32:S34-7.
15. Herzog AG, Klein P, Jacobs AR. Testosterone versus testosterone and testolactone in treating reproductive and sexual dysfunction in men with epilepsy and hypogonadism. Neurology 1998;50:782-4.
16. Mattson RH, Cramer JA, Collins JF, et al. Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. N Engl J Med 1985;313:145-51.
17. Mattson RH, Cramer JA, Collins JF. A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. The Department of Veterans Affairs Epilepsy Cooperative Study, No. 264 Group. N Engl J Med 1992;327:765-71.
18. Physicians' Desk Reference. 56th ed. Montvale: Medical Economics Co., 2002.
19. Montes JM, Ferrando L. Gabapentin-induced anorgasmia as a cause of noncompliance in a bipolar patient. Bipolar Disorders 2001;3:52.
20. Labbate LA, Rubey RN. Gabapentin-induced ejaculatory failure and anorgasmia. Am J Psychiatry 1999;156:972.
21. Brannon GE, Rolland PD. Anorgasmia in a patient with bipolar disorder type 1 treated with gabapentin. J Clin Psychopharmacol 2000;20:379-81.
22. Erfurth A, Amann B, Grunze H. Female genital disorder as adverse symptom of lamotrigine treatment. A serotoninergic effect? Neuropsychobiology 1998;38:200-1.
23. Husain AM, Carwile ST, Miller PP, Radtke RA. Improved sexual function in three men taking lamotrigine for epilepsy. South Med J 2000;93:335-6.
24. Herzog AG, Seibel MM, Schomer DL, Vaitukaitis JL, Geschwind N. Reproductive endocrine disorders in women with partial seizures of temporal lobe origin. Arch Neurol 1986;43:341-6.
25. Rodin E, Subramanian NG, Gilroy J. Investigation of sex hormones in male epileptic patients. Epilepsia 1984;25:690-4.
26. Spark RF, Willis CA, Royal H. Hypogonadism, hyperprolactinemia, and temporal lobe epilepsy in hyposexual men. Lancet 1984;1:413-7.
27. Cogen PH, Antunes JL, Correll JW. Reproductive function in temporal lobe epilepsy: the effect of temporal lobectomy. Surg Neurol 1979;12:243-6.
28. Taylor DC. Sexual behavior and temporal lobe epilepsy. Arch Neurol 1969;21:510-6.
29. Dansky LV, Andermann E, Andermann F. Marriage and fertility in epileptic patients. Epilepsia 1980;21:261-71.
30. Carran MA, Kohler CG, O'Connor MJ, Cloud B, Sperling MR. Marital status after epilepsy surgery. Epilepsia 1999;40:1755-60.
31. Morrell MJ, Guldner GT. Self-reported sexual function and sexual arousability in women with epilepsy. Epilepsia 1996;37:1204-11.
32. Souza EA, Keiralla DM, Silveira DC, Guerreiro CA. Sexual dysfunction in epilepsy: identifying the psychological variables. Arq Neuropsiquiatr 2000;58:214-20.
33. McGahuey CA, Gelenberg AJ, Laukes CA, et al. The Arizona sexual experience scale (ASEX): reliability and validity. J Sex Marital Ther 2000;26:25-40.
34. Munarriz R, Talakoub L, Flaherty E, et al. Androgen replacement therapy with dihydroepiandrosterone for androgen insuffciency and female sexual dysfunction: androgen and questionnaire results. J Sex Marital Ther 2002;28:165-73.
35. Guay AT. Decreased testosterone in regularly menstruating women with decreased libido: a clinical observation. J Sex Marital Ther 2001;27:513-9.