Effects of ethanol on an acetaldehyde drug discrimination with a conditioned taste aversion procedure

Alcohol

Volumn 28, Issue 2, 2002, Pages 103-109

  Redila, Van A ^a   Aliatas, Emmanuel ^a   Smith, Brian R ^a   Amit, Zalman ^a  

^a Gina Cody School of Engineering and Computer Science   (Canada)

Author keywords

Acetaldehyde; Conditioned taste aversion; Drug discrimination; Ethanol

Indexed keywords

ACETALDEHYDE; ALCOHOL; LITHIUM CHLORIDE; SACCHARIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG DISCRIMINATION; MALE; NONHUMAN; RAT; STIMULUS RESPONSE; TASK PERFORMANCE; TASTE AVERSION; TRAINING;

ACETALDEHYDE; ANIMALS; CONDITIONING (PSYCHOLOGY); DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; MALE; RATS; RATS, LONG-EVANS; TASTE;

ANIMALIA;

EID: 0036811424     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(02)00270-7     Document Type: Article

References (29)

1. Amit Z., Aragon C.M.G. Catalase activity measured in rats naive to ethanol correlates with later voluntary ethanol consumption. possible evidence for a biological marker system of ethanol intake Psychopharmacology (Berl). 95:1988;512-515.
2. Amit Z., Smith B.R., Weiss S. Catalase as a regulator of the propensity to ingest alcohol in genetically determined acatalasemic individuals from Israel. Addict Biol. 4:1999;215-221.
3. Aragon C.M.G., Abitbol M., Amit Z. Acetaldehyde may mediate reinforcement and aversion produced by ethanol. An examination using a conditioned taste-aversion paradigm. Neuropharmacology. 25:1986;79-83.
4. Aragon C.M.G., Abitbol M., Amit Z. Ethanol-induced CTA mediated by acetaldehyde through central catecholamine activity. Psychopharmacology (Berl). 103:1991;74-77. a.
5. Aragon C.M.G., Amit Z. The effect of 3-amino-1,2,4-triazole on voluntary ethanol consumption. evidence for brain catalase involvement in the mechanism of action Neuropharmacology. 31:1992;709-712.
6. Aragon C.M.G., Spivak K., Amit Z. Blockade of ethanol induced conditioned taste aversion by 3-amino-1,2,4-triazole. evidence for catalase mediated synthesis of acetaldehyde in rat brain Life Sci. 37:1985;2077-2084. a.
7. Aragon C.M.G., Spivak K., Amit Z. Effects of 3-amino-1,2,4-triazole in ethanol-induced narcosis, lethality and hypothermia in rats. Pharmacol Biochem Behav. 39:1991;55-59. b.
8. Aragon C.M.G., Sternklar G., Amit Z. A correlation between voluntary ethanol consumption and brain catalase activity in the rat. Alcohol. 2:1985;353-356. b.
9. Brown Z.W., Amit Z., Rockman G.E. Intraventricular self-administration of acetaldehyde, but not ethanol, in naive laboratory rats. Psychopharmacology (Berl). 64:1979;271-276.
10. Brown Z.W., Amit Z., Smith B. Intraventricular self-administration of acetaldehyde and voluntary consumption of ethanol in rats. Behav Neural Biol. 28:1980;150-155.
11. Brown Z.W., Amit Z., Smith B., Rockman G.E. Differential effects on conditioned taste aversion learning with peripherally and centrally administered acetaldehyde. Neuropharmacology. 17:1978;931-935.
12. Cohen G., Sinet P.M., Heikkila R. Ethanol oxidation by rat brain in vivo. Alcohol Clin Exp Res. 4:1980;366-370.
13. Gill K., Amit Z., Smith B.R. The regulation of alcohol consumption in rats. the role of alcohol-metabolizing enzymes - catalase and aldehyde dehydrogenase Alcohol. 13:1996;347-353.
14. Gill K., Menez J.F., Lucas D., Deitrich R.A. Enzymatic production of acetaldehyde from ethanol in rat brain tissue. Alcohol Clin Exp Res. 16:1992;910-915.
15. Herrera F.M., Velazquez Martinez D.N. Discriminative stimulus properties of amphetamine in a conditioned taste aversion paradigm. Behav Pharmacol. 8:1997;458-464.
16. Järbe T.U.C., Hiltunen A.J., Swedberg M.D.B. Ethanol as a discriminative stimulus. effects of cyanamide, acetaldehyde and chlormethiazole Med Biol. 60:1982;298-306.
17. Koechling U.M., Amit Z. Relationship between blood catalase activity and drinking history in a human population, a possible biological marker of the affinity to consume alcohol. Alcohol Alcohol. 27:1992;181-188.
18. Koechling U.M., Amit Z. Effects of 3-amino-1,2,4-triazole on brain catalase in the mediation of ethanol consumption in mice. Alcohol. 11:1994;235-239.
19. Koechling U.M., Amit Z., Negrete J.C. Family history of alcoholism and the mediation of alcohol intake by catalase; further evidence for catalase as a marker of the propensity to ingest alcohol. Alcohol Clin Exp Res. 19:1995;1096-1104.
20. Lucki I. Rapid discrimination of the stimulus properties of 5-hydroxytryptamine agonists using conditioned taste aversion. J Pharmacol Exp Ther. 247:1988;1120-1127.
21. Myers W.D., Ng K.T., Marzuki S., Myers R.D., Singer G. Alteration of alcohol drinking in the rat by peripherally self-administered acetaldehyde. Alcohol. 1:1984;229-236.
22. Myers W.D., Ng K.T., Singer G. Intravenous self-administration of acetaldehyde in the rat as a function of schedule, food deprivation and photoperiod. Pharmacol Biochem Behav. 17:1982;807-811.
23. Redila V.A., Smith B.R., Amit Z. The effects of aminotriazole and acetaldehyde on an ethanol drug discrimination with a conditioned taste aversion procedure. Alcohol. 21:2000;279-285.
24. Revusky S., Coombes S., Pohl R.W. Drug states as discriminative stimuli in a flavor-aversion learning experiment. J Comp Physiol Psychol. 96:1982;200-211.
25. Rodd-Henricks Z.A., Zaffaroni A., Goldstein A., McBride W.J., Li T.-K. Alcohol preferring (P) rats self-administer acetaldehyde directly into the posterior VTA. Alcohol Clin Exp Res. 24:2000;52A.
26. Rotzinger S., Smith B.R., Amit Z. Catalase inhibition attenuates the acquisition of ethanol and saccharin-quinine consumption in laboratory rats. Behav Pharmacol. 5:1994;203-209.
27. Smith B.R., Aragon C.M.G., Amit Z. Catalase and the production of central acetaldehyde. a possible mediator of the psychopharmacological effects of ethanol Addict Biol. 2:1997;277-289.
28. Smurthwaite S.T., Riley A.L. Nalorphine as a stimulus in drug discrimination learning. assessment of the role of μ and κ-receptor subtypes Pharmacol Biochem Behav. 48:1994;635-642.
29. Stevenson G.W., Pournaghash S., Riley A.L. Antagonism of drug discrimination learning within the conditioned taste aversion procedure. Pharmacol Biochem Behav. 41:1992;245-249.