Direct epicardial mapping can differentiate hibernating from scarred myocardium: A validation study with 18F-FDG-PET

Annals of Noninvasive Electrocardiology

Volumn 7, Issue 4, 2002, Pages 349-356

  Vahlhaus, Christian ^a   Schäfers, Michael ^a   Bruns, Hans Jürgen ^a   Janssen, Frauke ^a   Stypmann, Jörg ^a   Hammel, Dieter ^a   Scheld, Hans H ^a   Schober, Otmar ^a   Breithardt, Günter ^a   Wichter, Thomas ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Hibernating myocardium; Mapping

Indexed keywords

FLUORODEOXYGLUCOSE F 18; TETROFOSMIN TC 99M;

ADULT; AGED; ANGIOGRAPHY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY DISEASE; ELECTROCARDIOGRAPHY; EPICARDIUM MAPPING; FEMALE; HEART FUNCTION; HEART MUSCLE INJURY; HEART MUSCLE PERFUSION; HUMAN; MALE; MYOCARDIAL HIBERNATION; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; ROC CURVE; SCINTIGRAPHY; SENSITIVITY ANALYSIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

EID: 0036810922     PISSN: 1082720X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1542-474X.2002.tb00184.x     Document Type: Article

References (24)

1. Heusch G, Schulz R. Hibernating myocardium: A review. J Mol Cell Cardiol 1996;28:2359-2372.
2. Fuchs S, Kornowski R, Shiran A, et al. Electromechanical characterization of myocardial hibernation in a pig model. Coron Artery Dis 1999;10:195-198.
3. Callans DJ, Ren JF, Michele J, et al. Electroanatomic left ventricular mapping in the porcine model of healed anterior myocardial infarction: Correlation with intracardiac echocardiography and pathological analysis. Circulation 1999;100:1744-1750.
4. Bolli R, Zhu WX, Thornby JI, et al. Time course and determinants of recovery of function after reversible ischemia in conscious dogs. Am J Physiol 1988;254:H102-H114.
5. Knuuti MJ, Nuutila P, Ruotsalainen U, et al. Euglycemic hyperinsulinemic clamp and oral glucose load in stimulating myocardial glucose utilization during positron emission tomography. J Nucl Med 1992;33:1255-1262.
6. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: A method for quantifying insulin secretion and resistance. Am J Physiol 1979;237:E214-E223.
7. Gambhir SS, Schwaiger M, Huang SC, et al. Simple noninvasive quantification method for measuring myocardial glucose utilization in humans employing positron emission tomography and fluorine-18 deoxyglucose. J Nucl Med 1989;30:359-366.
8. Patlak CS, Blasberg RG. Graphical evaluation of blood-to-brain transfer constants from multiple- time uptake data. Generalizations. J Cereb Blood Flow Metab 1985;5:584-590.
9. Biedenstein S, Schafers M, Stegger L, et al. Three-dimensional contour detection of left ventricular myocardium using elastic surfaces. Eur J Nucl Med 1999;26:201-207.
10. Stegger L, Biedenstein S, Schafers KP, et al. Elastic surface contour detection for the measurement of ejection fraction in myocardial perfusion SPET. Eur J Nucl Med 2001;28:48-55.
11. Bruns HJ, Janssen F, Schäfers M, et al. Signal characteristics of multichannel epicardial electrograms in chronic ischemic and scarred myocardium: Electromechanical mismatch indicates viability in regions of myocardial dysfunction. Basic Res Cardiol 2001;96:98-105.
12. Heyndrickx GR, Millard RW, McRitchie RJ, et al. Regional myocardial functional and electrophysiological alterations after brief coronary artery occlusion in conscious dogs. J Clin Invest 1975;56:978-985.
13. Walton S. Radionuclide techniques for myocardial viability and hibernation. Heart 1999;81:6-7.
14. Narula J, Dawson MS, Singh BK, et al. Noninvasive characterization of stunned, hibernating, remodeled and nonviable myocardium in ischemic cardiomyopathy. J Am Coll Cardiol 2000;36:1913-1919.
15. Cigarroa CG, deFilippi CR, Brickner ME, et al. Dobutamine stress echocardiography identifies hibernating myocardium and predicts recovery of left ventricular function after coronary revascularization. Circulation 1993;88:430-436.
16. Kim RJ, Wu E, Rafael A, et al. The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med 2000;343:1445-1453.
17. Perrone-Filardi P, Pace L, Prastaro M, et al. Assessment of myocardial viability in patients with chronic coronary artery disease: Rest-4-hour-24-hour 201Tl tomography versus dobutamine echocardiography. Circulation 1996;94:2712-2719.
18. La Canna G, Rahimtoola SH, Visioli O, et al. Sensitivity, specificity, and predictive accuracies of noninvasive tests, singly and in combination, for diagnosis of hibernating myocardium. Eur Heart J 2000;21:1358-1367.
19. Rahimtoola SH. Coronary bypass surgery for chronic angina-1981. A perspective. Circulation 1982;65:225-241.
20. Rahimtoola SH. A perspective on the three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina. Circulation 1985;2:V123-V135.
21. Elsasser A, Schlepper M, Klovekorn WP, et al. Hibernating myocardium: An incomplete adaptation to ischemia. Circulation 1997;96:2920-2931.
22. Gunning MG, Chua TP, Harrington D, et al. Hibernating myocardium: Clinical and functional response to revascularization. Eur J Cardiothorac Surg 1997;11:1105-1112.
23. Afridi I, Grayburn PA, Panza JA, et al. Myocardial viability during dobutamine echocardiography predicts survival in patients with coronary artery disease and severe left ventricular systolic dysfunction. J Am Coll Cardiol 1998;32:921-926.
24. Oster HS, Taccardi B, Lux RL, et al. Electrocardiographic imaging: Noninvasive characterization of intramural myocardial activation from inverse-reconstructed epicardial potentials and electrograms. Circulation 1998;97:1496-1507.