Chronic acetaminophen toxicity: A case report and review of the literature

Journal of Emergency Medicine

Volumn 23, Issue 3, 2002, Pages 253-256

  Lane, Joshua E ^a   Belson, Martin G ^b   Brown, D Kaine ^a   Scheetz, Allison ^a  

^a MERCER UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetaminophen toxicity; Chronic; Hepatotoxicity; Poisoning

Indexed keywords

ACETYLCYSTEINE; CARISOPRODOL; CELECOXIB; CITALOPRAM; ESTRADIOL; FEXOFENADINE; GABAPENTIN; GLUCOSE; HYDROCODONE BITARTRATE PLUS PARACETAMOL; LACTULOSE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PENICILLIN G; VITAMIN K GROUP;

ADULT; ALCOHOL ABUSE; ALLERGY; ARTICLE; CASE REPORT; CERVICAL SPINE; CLINICAL FEATURE; DEPRESSION; DISEASE COURSE; DRUG OVERDOSE; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; LITERATURE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; RISK FACTOR; STOMACH BYPASS; TOXIC HEPATITIS; TREATMENT OUTCOME;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; FEMALE; HEPATITIS, TOXIC; HUMANS; MIDDLE AGED; POLYPHARMACY; TIME FACTORS;

EID: 0036806432     PISSN: 07364679     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-4679(02)00526-7     Document Type: Article

References (26)

1. Zimmerman H.J. Acetaminophen hepatotoxicity. Clin Liver Dis. 2:1998;523-541.
2. Seeff L.B., Cuccherini B.A., Zimmerman H.J., et al. Acetaminophen hepatotoxicity in alcoholics. A therapeutic misadventure. Ann Intern Med. 104:1986;399-404.
3. Barker J.D., de Carle D.J., Anuras S. Chronic excessive acetaminophen use and liver damage. Ann Intern Med. 87:1977;299-301.
4. McClain C.J., Holtzman J., Allen J., et al. Clinical features of acetaminophen toxicity. J Clin Gastroenterol. 10:1988;76-80.
5. Leist M.H., Gluskin L.E., Payne J.A. Enhanced toxicity of acetaminophen in alcoholics report of three cases . J Clin Gastroenterol. 7:1985;55-59.
6. Bray G.P., Harrison P.M., O'Grady J.G., et al. Long-term anticonvulsant therapy worsens outcome in paracetamol-induced fulminant hepatic failure. Hum Exp Toxicol. 11:1992;265-270.
7. Pessayre D., Wandscheer J.C., Cobert B., et al. Additive effects of inducers and fasting on acetaminophen hepatotoxicity. Biochem Pharmacol. 29:1980;2219-2223.
8. Ware A.J., Upchurch K., Eigenbrodt E., et al. Acetaminophen and the liver. Ann Intern Med. 88:1978;267-268.
9. Whitcomb D.C., Block G. Association of hepatotoxicity with fasting and ethanol use. JAMA. 272:1994;1845-1850.
10. th ed. 1998;541-542 Appleton and Lange, Stamford, CT.
11. Schiodt F.V., Rochling F.A., Casey D.L., et al. Acetaminophen toxicity in an urban county hospital. N Engl J Med. 337:1997;1112-1117.
12. Pershad J., Nichols M., King W. "The silent killer" chronic acetaminophen toxicity in a toddler . Pediatr Emerg Care. 1:1999;43-46.
13. Johnston S.C., Pelletier L.L. Enhanced hepatotoxicity of acetaminophen in the alcoholic patient. Two case reports and a review of the literature. Medicine. 76:1997;185-191.
14. Mitchell D.B., Acosta D., Bruckner J.V. Govt Reports Announcements and Index, Issue 13. 1986.
15. Mitchell J.R., Jollow D.J., Potter W.Z., et al. Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J Pharmacol Exp Ther. 187:1973;211-217.
16. Slattery J.T., Wilson J.M., Kalhorn T.F., et al. Dose-dependent pharmacokinetics of acetaminophen evidence of glutathione depletion in humans . Clin Pharmacol Ther. 41:1987;413-418.
17. Moulding T.S., Redeker A.G., Kanel G.C. Acetaminophen, isoniazid, and hepatic toxicity. Ann Intern Med. 114:1991;431.
18. Nolan C.M., Sandblom R.E., Thummel K.E., et al. Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis. Chest. 105:1994;408-411.
19. Minton N.A., Henry J.A., Frankel R.J. Fatal paracetamol poisoning in an epileptic. Hum Toxicol. 7:1988;33-34.
20. Piratte J.M. Apparent potentiation of hepatotoxicity from small doses of acetaminophen by phenobarbitol. [Letter] Ann Intern Med. 101:1984;403.
21. Bonkovsky H.L., Kane R.E., Jones D.P., et al. Acute hepatic and renal toxicty from low doses of acetaminophen in the absence of alcohol abuse or malnutrition evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency . Hepatology. 19:1994;1141-1148.
22. Makin A.J., Wendon J., Williams R. A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993). Gastroenterology. 109:1995;1907-1916.
23. Smilkstein M.J., Knapp G.L., Kulig K.W., Rumack B.H. Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose Analysis of the national multicenter study (1976-1985) . N Engl J Med. 319:1988;1557-1562.
24. Harrison P.M., Wendon J., Gimson A., et al. Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure. N Engl J Med. 324:1991;1852-1857.
25. Micromedex Healthcare Series 1974-2001. Vol. 108, expires 6/2001.
26. Mansour M.M., Fathi M.M. Effect of chronic administration of meprobamate on different enzymatic activities in liver and serum in rats. J Drug Res. 18:1989;189-200.