Effect of IVIgG treatment on fetal platelet count, HPA-1a titre and clinical outcome in a case of feto-maternal alloimmune thrombocytopenia

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 109, Issue 10, 2002, Pages 1195-1198

  Lucas, G F ^a   Hamon, M ^b   Carroll, S ^c   Soothill, P ^c  

^a NHS BLOOD AND TRANSPLANT   (United Kingdom)

^b DERRIFORD HOSPITAL   (United Kingdom)

^c ST MICHAEL'S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; HPA 1A ANTIBODY; IMMUNOGLOBULIN G; STEROID; UNCLASSIFIED DRUG;

ADULT; ALLOIMMUNITY; AMNIOCENTESIS; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENOTYPE; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; LABORATORY TEST; PRIORITY JOURNAL; SPLENECTOMY; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION; TREATMENT OUTCOME;

ANTIGENS, HUMAN PLATELET; AUTOIMMUNE DISEASES; FEMALE; FETAL BLOOD; FETOMATERNAL TRANSFUSION; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; PLATELET COUNT; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREGNANCY OUTCOME; THROMBOCYTOPENIA;

EID: 0036804735     PISSN: 14700328     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-0528.2002.01183.x     Document Type: Article

References (21)

1. Mueller-Eckhardt C., Kiefel V., Grubert Aet al. 348 cases of suspected neonatal alloimmune thrombocytopenia. Lancet. 1:1989;363-366.
2. Kaplan C., Daffos F., Forestier F., Morel M.C., Chesnel N., Tchernia G. Current trends in neonatal alloimmune thrombocytopenia: diagnosis and therapy. Kaplan-Gouet C., Schlegel N., Salmon C., MacGregor J. Platelet Immunology. Fundamentals and Clinical Aspects. 1991;267-278 John Libbey, Paris.
3. Murphy M.F., Waters A.H., Doughty HAet al. Antenatal management of fetomaternal alloimmune thrombocytopenia - report of 15 affected pregnancies. Transfus Med. 4:1994;281-292.
4. Menell J.S., Bussel J.B. Antenatal management of the thrombocytopenias. Clin Perinatol. 21:1994;591-614.
5. Bussel J., Berkowitz R., Lynch Let al. Antenatal treatment of alloimmune thrombocytopenia with intravenous gamma-globulin: a randomized trial of the addition of low-dose steroid to intravenous gamma-globulin. Am J Obstet Gynecol. 174:1996;1414-1423.
6. Lynch L., Bussel J.B., McFarland J.G., Chitkara U., Berkowitz L. Antenatal treatment of alloimmune thrombocytopenia. Obstet Gynecol. 80:1992;67-71.
7. Wenstrom K.D., Weiner C.P., Williamson R.A. Antenatal treatment of fetal alloimmune thrombocytopenia. Obstet Gynecol. 80:1992;433-435.
8. a) thrombocytopenic purpura. Thromb Haemost. 69:1993;1625A.
9. Nicolini U., Tannirandon Y., Gonzalez Pet al. Continuing controversy in alloimmune thrombocytopenia: fetal hyperimmunoglobulinemia fails to prevent thrombocytopenia. Am J Obstet Gynecol. 163:1990;1144-1146.
10. Mir N., Samson D., Kovar I.Z. Failure of high-dose immunoglobulin to improve fetal platelet count in neonatal allo-immune thrombocytopenia. Vox Sang. 55:1988;188-189.
11. Waters A.H., Ireland R., Mibashan RSet al. Fetal platelet transfusions in the management of alloimmune thrombocytopenia. Thromb Haemost. 58:1987;1178A.
12. von dem Borne AEG Kr, Verheught F.W.A., Oosterhof F., von Riesz E., Brutel de la Riviere A., Engelfriet C.P. A simple immunofluorescence test for the detection of platelet antibodies. Br J Haematol. 39:1978;195-207.
13. Kiefel V., Santoso S., Weisheit M., Mueller-Eckhardt C. Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelet-reactive antibodies. Blood. 70:1987;1722-1726.
14. Cavanagh G., Dunn A.N., Chapman C.E., Metcalfe P. HPA genotyping by PCR sequence-specific priming (PCR-SSP): a streamlined method for rapid routine investigations. Transfus Med. 7:1997;41-45.
15. Kaufman G.E., Paidas M.J. Rhesus sensitization and alloimmune thrombocytopenia. Semin Perinatol. 18:1994;333-349.
16. Segal M., Manning F.A., Harman C.R., Menticoglou S. Bleeding after intravascular transfusion: experimental and clinical observations. Am J Obstet Gynecol. 165:1991;1414-1418.
17. Urbaniak S., Duncan J.I., Armstrong-Fisher S.S., Abramovich D.R., Page K.R. Variable inhibition of placental IgG transfer in vitro with commercial IVIgG preparations. Br J Haematol. 107:1999;815-817.
18. Husson-van Kliet J., Druyts-Voets E. Maternal foetal immune relationship: another point of view. Vox Sang. 55:1988;116-118.
19. Morales JW, Stroup M. Intracranial hemorrhage in utero due to isoimmune neonatal thrombocytopenia. Obstet Gynecol 65:20S-21S.
20. Giovangrandi Y., Daffos F., Kaplan C. Very early intracranial haemorrhage in alloimmune thrombocytopenia. Lancet. ii:1990;310.
21. Letsky E.A., Greaves M. Guidelines on the investigation and management of thrombocytopenia in pregnancy in neonatal alloimmune thrombocytopenia. Br J Haematol. 95:1996;21-26.