NZF-2b is a novel predominant form of mouse NZF-2/MyT1, expressed in differentiated neurons especially at higher levels in newly generated ones

Mechanisms of Development

Volumn 118, Issue 1-2, 2002, Pages 209-213

  Matsushita, Fumio ^a   Kameyama, Toshiki ^a   Marunouchi, Tohru ^a  

^a FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

Brain; C2HC type zinc finger; Central nervous system; Development; Dorsal root ganglia; Mouse; MyT1; Neurogenesis; Neuronal differentiation; NZF 2; Peripheral ganglia; Peripheral nervous system; Spinal cord; Transcription factor

Indexed keywords

NEURAL ZINC FINGER 2B PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; DNA BINDING PROTEIN; MYT1 PROTEIN, MOUSE; ZINC FINGER PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZINC FINGER MOTIF; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL DIFFERENTIATION; GENETIC TRANSCRIPTION; GENETICS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; METABOLISM; MOLECULAR GENETICS; MOUSE; NERVE CELL; NERVOUS SYSTEM; PRENATAL DEVELOPMENT; PROTEIN MOTIF; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SPINAL CORD; TIME;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NERVOUS SYSTEM; NEURONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; SPINAL CORD; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; ZINC FINGERS;

EID: 0036803183     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(02)00250-2     Document Type: Article

References (11)

1. Altman J., Bayer S.A. The development of the rat spinal cord. Adv. Anat. Embryol. Cell. Biol. 85:1984;1-164.
2. Armstrong R.C., Kim J.G., Hudson L.D. Expression of myelin transcription factor I (MyTI), a 'zinc-finger' DNA-binding protein, in developing oligodendrocytes. Glia. 14:1995;303-321.
3. Bellefroid E.J., Bourguignon C., Hollemann T., Ma Q., Anderson D.J., Kintner C., Pieler T. X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiation. Cell. 87:1996;1191-1202.
4. Garel S., Marin F., Mattei M.G., Vesque C., Vincent A., Charnay P. Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system. Dev. Dyn. 210:1997;191-205.
5. Jiang Y., Yu V.C., Buchholz F., O'Connell S., Rhodes S.J., Candeloro C., Xia Y.R., Lusis A.J., Rosenfeld M.G. A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland. J. Biol. Chem. 271:1996;10723-10730.
6. Kameyama T., Murakami Y., Suto F., Kawakami A., Takagi S., Hirata T., Fujisawa H. Identification of a neuronal cell surface molecule, plexin, in mice. Biochem. Biophys. Res. Commun. 226:1996;524-529.
7. Kim J.G., Armstrong R.C., Agoston D.v., Robinsky A., Wiese C., Nagle J., Hudson L.D. Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. J. Neurosci. Res. 50:1997;272-290.
8. Kim J.G., Hudson L.D. Novel member of the zinc finger superfamily: a C2-HC finger that recognizes a glia-specific gene. Mol. Cell. Biol. 12:1992;5632-5639.
9. Nagase T., Ishikawa K., Suyama M., Kikuno R., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. Prediction of the coding sequences of unidentified human genes. DNA Res. 5:1998;355-364.
10. Weiner J.A., Chun J. Png-1, a nervous system-specific zinc finger gene, identifies regions containing postmitotic neurons during mammalian embryonic development. J. Comp. Neurol. 381:1997;130-142.
11. Yee K.S., Yu V.C. Isolation and characterization of a novel member of the neural zinc finger factor/myelin transcription factor family with transcriptional repression activity. J. Biol. Chem. 273:1998;5366-5374.