Pretreatment of rats with the inducing agents phenobarbitone and 3-methylcholanthrene ameliorates the toxicity of chromium (VI) in hepatocytes

Toxicology in Vitro

Volumn 16, Issue 5, 2002, Pages 509-516

  Gunaratnam, M ^a   Pohlscheidt, M ^a   Grant, M H ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

3 Methylcholanthrene; Chromium (VI) toxicity; Hepatocytes; Inducing agents; Phenobarbitone

Indexed keywords

3 METHYLCHOLANTHRENE; CHROMIUM DERIVATIVE; CYTOCHROME P450; ENZYME INDUCING AGENT; GLUTATHIONE; GLUTATHIONE REDUCTASE; PHENOBARBITAL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG RESPONSE; ENZYME ACTIVITY; ENZYME INDUCTION; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; PROTEIN CONTENT; RAT; REDUCTION;

ANIMALS; CARCINOGENS, ENVIRONMENTAL; CELL SURVIVAL; CELLS, CULTURED; CHROMIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; GLUTATHIONE; GLUTATHIONE REDUCTASE; HEPATOCYTES; MALE; METHYLCHOLANTHRENE; NAD(P)H DEHYDROGENASE (QUINONE); NADPH-FERRIHEMOPROTEIN REDUCTASE; PHENOBARBITAL; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0036801766     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(02)00040-1     Document Type: Article

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