Histopathological studies on the effects of peroxynitrite on the lungs and trachea of rabbits

European Respiratory Journal

Volumn 20, Issue 4, 2002, Pages 1014-1016

  Farshid, A A ^a   Sadeghi Hashjin, G ^a   Ferdowsi, H R ^a  

^a URMIA UNIVERSITY   (Iran)

Author keywords

Lungs; Oxygen radicals; Pathology; Peroxynitrite; Rabbit; Trachea

Indexed keywords

PEROXYNITRITE; THIOPENTAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; DEGENERATION; DISEASE COURSE; HISTOPATHOLOGY; INOCULATION; ISOLATED LUNG; ISOLATED ORGAN; LUNG CONGESTION; LUNG DISEASE; LUNG EXTRAVASCULAR FLUID; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RABBIT; TRACHEA; TRACHEA DISEASE; TRACHEA INJURY; TRACHEA MUCOSA;

ANESTHETICS, INTRAVENOUS; ANIMALS; CULTURE TECHNIQUES; FEMALE; IMMUNOHISTOCHEMISTRY; LUNG; MALE; MODELS, ANIMAL; PEROXYNITROUS ACID; RABBITS; RANDOM ALLOCATION; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; THIOPENTAL; TRACHEA;

EID: 0036798983     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.02.00264102     Document Type: Article

References (10)

1. Muijsers RBR, Folkerts G, Henricks PAJ, Sadeghi-Hashjin G, Nijkamp FP. Peroxynitrite: a two-faced metabolite of nitric oxide. Life Sci 1997; 60: 1833-1845.
2. Sadeghi-Hashjin G, Folkerts G, Henricks PAJ, Muijsers RBR, Nijkamp FP. Peroxynitrite in airway disease. Clin Exp Allergy 1998; 28: 1464-1473.
3. Rubbo H, Radi R, Trujillo M, et al. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. J Biol Chem 1994; 269: 26066-26075.
4. Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. J Biol Chem 1991; 266: 4244-4250.
5. Hu P, Ischiropoulos H, Beckman JS, Matalon S. Peroxynitrite inhibition of oxygen consumption and sodium transport in alveolar type II cells. Am J Physiol 1994; 266: L628-L634.
6. Sadeghi-Hashjin G, Folkerts G, Henricks PAJ, et al. Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo. Am J Respir Crit Care Med 1996; 153: 1697-1701.
7. Marla SS, Lee J, Groves JT. Peroxynitrite rapidly permeates phospholipid membranes. Proc Natl Acad Sci USA 1997; 94: 14243-14248.
8. Denicola A, Rubbo H, Rodriguez D, Radi R. Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi. Arch Biochem Biophys 1997; 304: 279-286.
9. -); an in vivo study in the rabbit. In: Abstracts: 14th Iranian Congress of Physiol & Pharmacol. Tehran, Tehran University of Medical Sciences, 1999; p. 180.
10. Sadeghi-Hashjin G, Henricks PAJ, Folkerts G, Muis Garssen J, Nijkamp FP. Role of the epithelial layer in the generation of superoxide anion by the guinea pig isolated trachea. Mediator Inflam 1998; 7: 35-40.