A prospective randomized comparison of sequential versus monoculture systems for in-vitro human blastocyst development

Human Reproduction

Volumn 17, Issue 10, 2002, Pages 2700-2705

  Macklon, N S ^a   Pieters, M H E C ^a   Hassan, M A ^a   Jeucken, P H M ^a   Eijkemans, M J C ^a   Fauser, B C J M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Blastocyst; Culture medium; IVF; Pregnancy rates; Randomized controlled trial

Indexed keywords

CHORIONIC GONADOTROPIN; RECOMBINANT FOLLITROPIN; TRIPTORELIN;

ADULT; ARTICLE; BLASTOCYST; BLASTULA; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; EMBRYO CULTURE; EMBRYO TRANSFER; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MONOCULTURE; NIDATION; PREGNANCY RATE; PREIMPLANTATION EMBRYO; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SEQUENTIAL CULTURE;

EID: 0036796226     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/17.10.2700     Document Type: Article

References (58)

1. Almagor, M., Bejar, C., Kafka, I. and Yaffe, H. (1996) Pregnancy rates after communal growth of pre-implantation human embryos in vitro. Fertil. Steril., 66, 394-397.
2. Barnes, F.L., Crombie, A., Gardner, D.K., Kausche, A., Lacham-Kaplan, O., Suikkari, A.M., Tiglias, J., Wood, C. and Trounson, A.O. (1995) Blastocyst development and birth after in-vitro maturation of human primary oocytes, intracytoplasmic sperm injection and assisted hatching. Hum. Reprod., 10, 3243-3247.
3. 2 environment. Fertil. Steril., 70 (Suppl. 1), Abstract 0-262.
4. Behr, B., Pool, T.B., Milki, A.A., Moore, D., Gebhardt, J. and Dasig, D. (1999) Preliminary clinical experience with human blastocyst development in vitro without co-culture. Hum. Reprod., 14, 454-457.
5. Bolton, V.N., Hawes, S.M. and Taylor, C.T. (1989) Development of spare human preimplantation embryos in vitro: an analysis of the correlations among gross morphology, cleavage rates and development to the blastocyst. J. In Vitro Fertil. Embryo Transfer, 6, 30-35.
6. Bolton, V.N., Wren, M.E. and Parsons, J.H. (1991) Pregnancies after in vitro fertilisation and transfer of human blastocysts. Fertil. Steril., 55, 830-832.
7. Desai, N., Sheean, L., Martin, D., Gindlesperger, V., Austin, C.M., Lisbonna, H., Peskin, B. and Goldfarb, J.M. (1996) Clinical experience with synthetic serum substitute as a protein supplement in IVF culture media: a retrospective study. J. Assist. Reprod. Genet., 13, 23-31.
8. Edwards, R.G., Purdy, J.M., Steptoe, P.C. and Walters, D.E. (1981) The growth of human preimplantation embryos in vitro. Am. J. Obstet. Gynecol., 15, 408-416.
9. Fauser, B.C.J.M., Devroey, P., Yen, S.S.C., Gosden, R., Crowley, W.F. Jr, Baird, D.T., Bouchard, P. (1999) Minimal ovarian stimulation for IVF: appraisal of potential benefits and drawbacks. Hum. Reprod., 14, 2681-2686.
10. FitzGerald, L. and DiMattina, M. (1992) An improved medium for long-term culture of human embryos overcomes the in-vitro developmental block and increases blastocyst formation. Fertil. Steril., 57, 641-647.
11. Fong, C.Y., Bongso, A., Ng, S.C., Anandakumar, C., Trounson, A. and Ratnam, S. (1997) Ongoing normal pregnancy after transfer of zone free blastocysts: implications for the embryo transfer in the human. Hum. Reprod., 12, 557-560.
12. Fong, C.Y., Bongso, A., Ng, S.C., Kumar, J., Trouson, A. and Ratnam, S. (1998) Blastocyst transfer after enzymatic treatment of zona pellucida: improving IVF and understanding implantation. Hum. Reprod., 13, 2926-2932
13. Gardner, D.K. (1998) Changes in requirements and utilisation of nutrients during mammalian preimplantation embryo development and their significance in embryo culture. Theriogenology, 49, 83-102.
14. Gardner, D.K. and Lane, M. (1997) Culture and selection of viable blastocysts: a feasible proposition for human IVF. Hum. Reprod. Update, 3, 367-382.
15. Gardner, D.K., Lane, M.W. and Lane, M. (1997) Development of the inner cell mass in mouse blastocysts is stimulated by reducing the embryo: incubation volume ratio. Hum. Reprod., 12 (Abstract Bk. 1), pp. 182-183.
16. Gardner, D.K. and Lane, M. (2001) Embryo culture. In Gardner, D.K., Weissmann, A., Howles, C.M. and Shoham, Z. (eds), Textbook of Assisted Reproductive Technologies. Laboratory and Clinical Perspectives. Martin Dunitz, London, pp. 203-222.
17. Gardner, D.K., Lane, M., Spitzer, A. and Batt, P.A. (1994) Enhanced rates of cleavage and development for the sheep zygotes cultured to the blastocyst stage in vitro in the absence of serum or somatic cells: amino acids, vitamins and culturing embryos in groups stimulate development. Biol. Reprod., 50, 390-400.
18. Gardner, D.K., Lane, M., Calderon, I. and Leeton, J. (1996) Environment of the preimplantation embryo in vivo: metabolite analysis of the oviduct and uterine fluids during the menstrual cycle and metabolism of cumulus cells. Fertil. Steril., 65, 349-353.
19. Gardner, D.K., Vella, P., Lane, M., Wagley, L., Schlenker, T. and Schoolcraft, W.B. (1998a) Culture and transfer of human blastocysts increases implantation rates and reduces the need for multiple embryo transfers. Fertil. Steril., 69, 84-88.
20. Gardner, D.K., Schoolcraft, W.B., Wagley, L., Schlenker, T., Stevens, J., and Hesla, J. (1998b) A prospective randomized trial of blastocyst culture and transfer in in-vitro fertilization. Hum. Reprod., 13, 3434-3440.
21. Gardner, D.K. and Lane, M. and Schoolcraft, W.B. (2000a) Culture and transfer of viable blastocysts: a feasible proposition for human IVF. Hum. Reprod., 15 (Suppl. 6), 9-23.
22. Gardner, D.K., Lane, M. Stevens, J., Schlenker, T. and Schoolcraft, W.B. (2000b) Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer. Fertil. Steril., 73, 1155-1158.
23. Giscard d'Estaing, S., Lornage, J., Hadj, S., Boulieu, D., Salle, B. and Guerin, J. (2001) Comparison of two blastocyst culture systems: coculture on Vero cells and sequential media. Fertil. Steril., 76, 1032-1035.
24. Gott, A.L., Hardy, K., Winston, R.M. and Leese, H.J. (1990) Non-invasive measurement of pyruvate and glucose uptake and lactate production by single human preimplantation embryos. Hum. Reprod., 5, 104-108.
25. Hardy, K., Handyside, A.H. and Winston, R.M.L. (1989a) The human blastocyst: cell number, death and allocation during the late pre implantation development in vitro. Development, 107, 597-604.
26. Hardy, K., Hooper, M.A., Handyside, A.H., Rutherford, A.J., Winston, R.M. and Leese, H.J. (1989b) Non-invasive measurement of glucose and pyruvate uptake by individual human oocytes and preimplantation embryos. Hum. Reprod., 4, 188-191.
27. Hewitson, L.C. and Leese, H.J. (1993) Energy metabolism of the trophectoderm and inner cell mass of the mouse blastocyst. J. Exp. Zool., 267, 337-343.
28. Huisman, G.J., Lo-A-Njoe, N., Alberda, A.T., Leerentveld, R.A., Verhoeff, A. and Zeilmaker, G.H. (1992) Comparison of results obtained with human serum and a protein solution as a supplement for in vitro fertilization culture medium. Fertil. Steril., 58, 637-639.
29. Huisman, G.J., Alberda, A., Leerentveld, R.A., Verhoeff, A. and Zeilmaker, G.H. (1994) A comparison of in vitro fertilization results after embryo transfer after 2, 3 and 4 days of culture. Fertil. Steril., 61, 970-971.
30. Huisman, G.J., Fauser, B.C.J.M., Eijkemans, M.J. and Pieters, M.H. (2000) Implantation rates after in vitro fertilization and transfer of a maximum of two embryos that have undergone three to five days of culture. Fertil. Steril., 73, 117-122.
31. Jones, G.M. and Trounson, A.O. (1999) Blastocyst stage transfers: pitfalls and benefits. The benefits of extended culture. Hum. Reprod., 14, 1405-1408.
32. Jones, G.M., Trounson, A.O., Gardner, D.K. Kausche, A., Lolatgis, N. and Wood, C. (1998a) Evolution of a culture protocol for successful blastocyst development and pregnancy. Hum. Reprod., 13, 169-177.
33. Jones, G.M., Trounson, A.O., Lolagatis, N. and Wood, C. (1998b) Factors affecting the success of human blastocyst development and pregnancy following in vitro fertilization and embryo transfer. Fertil. Steril., 70, 1022-1029.
34. Karaki, R.Z., Samarraie, S.S., Younis, N.A., Lahloub, T.M. and Ibrahim, M.H. (2002) Blastocyst culture and transfer: a step toward improved in vitro fertilization outcome. Fertil. Steril., 77, 114-118.
35. Kola, I., Sathanathan, A.H. and Gras, L. (1993) Chromosomal analysis of preimplantation mammalian embryos. In Trounson, A. and Gardner, D.K. (eds), Handbook of In Vitro Fertilisation. CRC Press, Boca Raton, Florida, p. 173
36. Lane, M. and Gardner, D.K. (1997a) Differential regulation of mouse embryo development and viability by amino acids. J. Reprod. Fertil., 109, 153-164.
37. Lane, M. and Gardner, D.K. (1997b) EDTA stimulates development of cleavage stage mouse embryos by inhibiting the glycolytic enzyme phosphoglycerate kinase. Biol. Reprod., 57 (Suppl. 1), 193.
38. Leese, H.J., Hooper, M.A., Edwards, R.G. and Ashwood-Smith, M.J. (1986) Uptake of pyruvate by early human embryos determined by a non-invasive technique. Hum. Reprod., 1, 181-182.
39. Marek, D., Langley, M., Gardner, D.K., Confer, N., Doody, K.M. and Doody, K.J. (1999) Introduction of blastocyst culture and transfer for all patients in an in vitro fertilization program. Fertil. Steril., 72, 1035-1040.
40. Ménézo, Y. and Benn Khalifa, M. (1995) Cytogenetic and cryobiology of human co-cultured embryos: a 3-year experience. J. Assist. Reprod. Genet., 12, 35-40.
41. Ménézo, Y.J., Guerin, J.F. and Czyba, J.C. (1990) Improvement of human early embryo development in vitro by co-culture on mono layers of vero cells. Biol. Reprod., 42, 301-306.
42. Ménézo, Y., Hazout, A., Dumont, M., Herbaut, N., Nicollet, B. (1992) Co-culture of embryos on Vero cells and transfer of blastocysts in humans. Hum. Reprod., 7,(Suppl. 1), 101-106.
43. Ménézo, Y., Hamamah, S., Hazout, A. and Dale, B. (1998) Time to switch from co-culture to sequential defined media for transfer at the blastocyst stage. Hum. Reprod., 13, 2043-2044.
44. Milki, A.A., Fisch, J.D. and Behr, B. (1999) Two-blastocyst transfer has similar pregnancy rates and a decreased multiple gestation rate compared with three-blastocyst transfer. Fertil. Steril., 72, 225-228.
45. Milki, A.A., Hinkley, M.D., Fisch, J.D., Dasig, D. and Behr, B. (2000) Comparison of blastocyst transfer with day 3 embryo transfer in similar patient populations. Fertil. Steril., 73, 126-129.
46. Moessner, J. and Dodson, W. (1995) The quality of human embryo growth is improved when embryos are cultured in groups rather than separately. Fertil. Steril., 64, 1034-1035.
47. Munné, S., Alikani, M., Tomkin, G., Grifo, J. and Cohen, J. (1995) Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities. Fertil. Steril., 64, 382-391.
48. Paria, B.C. and Dey, S.K. (1990) Pre-implantation embryo development in vitro: cooperative interactions among embryos and the role of growth factors. Dev. Biol., 7, 4756-4760.
49. Plachot, M., Belaisch-Allart, J, Mayenga, J.M., Chouraqui, A., Serkine, A.M. and Tesquier, L. (2000) Blastocyst stage transfer: the real benefits compared with early embryo transfer. Hum. Reprod., 15 (Suppl. 6), 24-30.
50. Sandalinas, M., Sadowy, S., Alikani, M., Calderon, G., Cohen, J. and Munné, S. (2001) Developmental ability of chromosomally abnormal human embryos to develop to the blastocyst stage. Hum. Reprod., 16, 1954-1958.
51. Scholtes, M.C.W. and Zeilmaker, G.H. (1996) A prospective randomised study of embryo transfer results after 3 or 5 days of embryo culture in in vitro fertilisation. Fertil. Steril., 65, 1245-1248.
52. Shapiro, B.S., Richter, K.S., Dee, C., Harris, M.T. and Daneshmand, S.T. (2001) A comparison of day 5 and day 6 blastocyst transfers. Fertil. Steril., 75, 1126-1130.
53. Shoukir, Y., Chardonnens, D., Campana, A., Bischof, P. and Sakkas, D. (1998) The rate of development and time of transfer play different roles in influencing the viability of human blastocysts. Hum. Reprod., 13, 676-681.
54. Steptoe, P.C., Edwards, R.G. and Purdy, J.M. (1971) Human blastocysts grown in culture. Nature, 229, 132-133.
55. Van Blerkom, J. (1994) Developmental failure in human reproduction associated with chromosomal abnormalities and cytoplasmic pathologies in meiotically mature oocytes. In Van Blerkom, J. (ed.), The Biological Basis of Early Human Reproductive Failure. Oxford University Press, New York, 283 pp.
56. Van Langendonckt, A.V., Demylle, D. Wyns, C. Nisolle, M. and Donnez, J. (2001) Comparison of G1.2/G2.2 and Sydney IVF cleavage/blastocyst sequentila media for the culture of human embryos: a prospective, randomized, comparative study. Fertil. Steril., 76, 102310-102331.
57. Veeck, L.L. (1998) An Atlas of Human Gametes and Conceptuses. Parthenon Publishing, New York, 40 pp.
58. Zeilmaker, G.H. (1986) The laboratory procedure of in-vitro fertilization: some observations and conclusions. In Nunez, J., Dumont, J.E. and King, R.J.B. (eds), Hormones and Cell Regulation. John Libbey Eurotext, London, 43 pp.