Could stent design affect platelet activation? Results of the Platelet Activation in Stenting (PAST) study

Journal of Invasive Cardiology

Volumn 14, Issue 10, 2002, Pages 584-589

  Gurbel, Paul A ^a   Callahan, Kevin P ^a   Malinin, Alex I ^a   Serebruany, Victor L ^a   Gillis, Jeremy ^a  

^a SINAI CENTER FOR THROMBOSIS RESEARCH   (United States)

Author keywords

Platelet aggregation; Stent design

Indexed keywords

ADENOSINE DIPHOSPHATE; CD151 ANTIGEN; CD31 ANTIGEN; LEUKOCYTE ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PROTEIN; PROTEIN PAC 1; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY STENT; EXPLANT; HUMAN; IMPLANTATION; LEUKOCYTE AGGREGATION; MAJOR CLINICAL STUDY; PILOT STUDY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

AGED; ANIMALS; ANTIGENS, CD; CORONARY ARTERIOSCLEROSIS; EQUIPMENT DESIGN; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; PILOT PROJECTS; PLATELET ACTIVATION; PLATELET AGGREGATION; PROSPECTIVE STUDIES; STENTS; SWINE;

EID: 0036795770     PISSN: 10423931     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Gawaz M, Neumann FJ, Ott I, et al. Platelet activation and coronary stent implantation. Effect on antithrombotic therapy. Circulation 1996;94:279-285.
2. Gurbel PA, Cummings CC, Alford AB, et al. Onset and extent of platelet inhibition by loading dose clopidogrel in patients undergoing elective coronary stenting: The PRONTO (Plavix for Reduction of New Thrombus Occurrence) trial (Abstr). J Am Coll Cardiol 2001;37:32A.
3. Steinhubl SR, Ellis SG, Wolski K, et al. Ticlopidine pretreatment before coronary stenting is associated with sustained decrease in adverse cardiac events: Data from the Evaluation of Platelet IIb/IIIa Inhibitor for Stenting (EPISTENT) Trial. Circulation 2001;103:1403-1409.
4. Schomig A, Neumann FJ, Kastrati A, et al. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary artery stents. N Engl J Med 1996;334:1084-1089.
5. LeBreton H, Plow EF, Topol EJ. Role of platelets in restenosis after percutaneous coronary revascularization. J Am Coll Cardiol 1996;28:1643-1651.
6. Farb A, Sangorgi G, Carter AJ, et al. Pathology of acute and chronic coronary stenting in humans. Circulation 1999;99:44-52.
7. Gutensohn K, Beythein C, Bau J, et al. In vitro analysis of diamond-like carbon coated stents. Reduction of metal ion release, platelet activation and thrombogenicity. Thromb Res 2000;99:577-585.
8. Garasic JM, Edelman ER, Squire JC, et al. Stent and artery geometry determine intimal thickening independent of arterial injury. Circulation 2000;101:812-818.
9. Monnink. SH, van Boven AJ, Peels Ho, et al. Silicon-carbide coated coronary stents have low platelet and leukocyte adhesion during platelet activation. J Invest Med 1999;47:304-310.
10. Beythein C, Gutensohn K, Bau J, et al. Influence of stent length and heparin coating on platelet activation: A flow cytometric analysis in a pulsed floating model. Thromb Res 1999;94:79-86.
11. Tamok A, Mahnke A, Muller H, Zotz RJ. Rapid in vitro biocompatibility assay of endovascular stents by flow cytometry using platelet activation and platelet leukocyte aggregation. Cytometry 1999;38:30-39.
12. Gurbel PA, Serebruany VL, Shustov AR, et al., for the GUSTO III Investigators. Effects of reteplase and alteplase on platelet aggregation and major receptor expression during the first 24 hours of acute myocardial infarction treatment. J Am Coll Cardiol 1998;31:1466-1473.
13. Ruggeri ZM. New insights into the mechanisms of platelet adhesion and aggregation. Semin Hematol 1994;31:29-39.
14. Serebruany VL, Cummings CC, Malinin Al, et al. Uniform platelet activation exists before stent implantation despite aspirin therapy. Am Heart J 2001;142:611-616.
15. Gawaz M, Neumann FJ, Schomig A. Evaluation of platelet membrane glycoproteins in coronary artery disease: Consequences for diagnosis and therapy. Circulation 1999;99:E1-E11.
16. Varon D, Jackson DE, Shenkman B, et al. Platelet/endothelial cell adhesion molecule-1 serves as a co-stimulatory agonist receptor that modulates integrin-dependent adhesion and aggregation of human platelets. Blood 1998;91:500-507.
17. Sueyoshi S, Sawada R, Fukuda M. Carbohydrate structures of recombinant soluble lamp-1 and leukosialin containing sialyl Le(x) terminus. Bioorg Med Chem 1994;2:1331-1338.
18. Sincock PM, Mayrhofer G, Ashman LK. Localization of transmembrane 4 superfamily (TM4SF) member PETA-3 (CD 151) in normal human tissues: Comparison with CD 9, CD 63 and α5β1 integrin. J Histochem Cytochem 1997;45:515-525.
19. Gurbel PA, Kereiakes DJ, Dalesandro MR, et al. Role of soluble and platelet-bound p-selectin in discriminating cardiac from non-cardiac chest pain at presentation in the emergency department. Am Heart J 2000;139:320-328.
20. Michelson AD, Bamard MR, Krueger LA, et al. Circulating monocyte-platelet aggregates are a more sensitive marker of platelet activation than platelet surface p-selectin: Studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation 2001;104:1533-1537.
21. Neumann FJ, Hochholzer W, Pogatsa-Murray G, et al. Antiplatelet effects of abciximab, tirofiban and eptifibatide in patients undergoing coronary stenting. J Am Coll Cardiol 2001;37:1323-1328.
22. Atalar E, Aytemir K, Haznedaroglu I, et al. Platelet and leukocyte deactivation after intracoronary stent placement in patients receiving combined antiplatelet therapy. Clin Appl Thromb Hemost 2001;7:116-121.
23. Makkar RR, Eigler NL, Kaul S, et al. Effects of clopidogrel, aspirin and combined therapy in a porcine ex vivo model of high-shear induced stent thrombosis. Eur Heart J 1998;19:1538-1546.
24. Gutensohn K, Beythein C, Bau J, et al. Tantalum stents induce expression of GMP 140 and GP 53 on platelets after contact in an in vitro model. Beitr Infusionsther Transfusionsmed 1996;33:61-65.
25. Gawaz M, Neumann FJ, Ott I, et al. Role of activation-dependent platelet membrane glycoproteins in development of subacute occlusive coronary stent thrombosis. Coron Artery Dis 1997;8:121-128.