A biosensor for theophylline based on fluorescence detection of ligand-induced hammerhead ribozyme cleavage

RNA

Volumn 8, Issue 10, 2002, Pages 1242-1252

  Sekella, Phillip T ^a   Rueda, David ^a   Walter, Nils G ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Activity assay; Asthma; Bronchodilator; Catalytic RNA; Fluorescence resonance energy transfer; RNA conformational change

Indexed keywords

CAFFEINE; LIGAND; RIBOZYME; THEOPHYLLINE;

ALLOSTERISM; ARTICLE; BIOSENSOR; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME REGULATION; ENZYME STABILITY; ENZYME SUBSTRATE; FLUORESCENCE; LIGAND BINDING; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN;

BASE PAIRING; BASE SEQUENCE; BINDING SITES; BIOSENSING TECHNIQUES; CAFFEINE; FLUORESCENCE RESONANCE ENERGY TRANSFER; LIGANDS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; RNA; RNA, CATALYTIC; SENSITIVITY AND SPECIFICITY; THEOPHYLLINE;

EID: 0036795275     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838202028066     Document Type: Article

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