-
1
-
-
0023584049
-
The isolation and structure of a remarkable marine animal antineoplastic constituent: Dolastatin-10
-
Pettit GR, Kamano Y, Herald CL, et al. The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin-10. J Am Chem Soc 1987;109:6883-5.
-
(1987)
J Am Chem Soc
, vol.109
, pp. 6883-6885
-
-
Pettit, G.R.1
Kamano, Y.2
Herald, C.L.3
-
2
-
-
0025352537
-
Dolastatin-10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain
-
Bai R, Pettit GR, Hamel E. Dolastatin-10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain. Biochem Pharmacol 1990;39:1941-9.
-
(1990)
Biochem Pharmacol
, vol.39
, pp. 1941-1949
-
-
Bai, R.1
Pettit, G.R.2
Hamel, E.3
-
3
-
-
0032950658
-
Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: Induction of apoptosis and bcl-2 modification
-
Kalemkerian GP, Ou X, Adil MR, et al. Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: induction of apoptosis and bcl-2 modification. Cancer Chemother Pharmacol 1999;43:507-15.
-
(1999)
Cancer Chemother Pharmacol
, vol.43
, pp. 507-515
-
-
Kalemkerian, G.P.1
Ou, X.2
Adil, M.R.3
-
5
-
-
0029953141
-
Antitumor evaluation of dolastatins 10 and 15 and their measurement in plasma by radioimmunoassay
-
Aherne GW, Hardcastle A, Valenti M, et al. Antitumor evaluation of dolastatins 10 and 15 and their measurement in plasma by radioimmunoassay. Cancer Chemother Pharmacol 1996;38:225-32.
-
(1996)
Cancer Chemother Pharmacol
, vol.38
, pp. 225-232
-
-
Aherne, G.W.1
Hardcastle, A.2
Valenti, M.3
-
6
-
-
0033002547
-
Phase I trial of dolastatin-10 (NSC 376128) in patients with advanced solid tumors
-
Pitot HC, McElroy EA, Reid JM, et al. Phase I trial of dolastatin-10 (NSC 376128) in patients with advanced solid tumors. Clin Cancer Res 1999;5:525-31.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 525-531
-
-
Pitot, H.C.1
McElroy, E.A.2
Reid, J.M.3
-
7
-
-
0034005620
-
Novel marine-derived anticancer agents: A phase I clinical pharmacological, and pharmacodynamic study of dolastatin 10 (NSC 376128) in patients with advanced solid tumors
-
Madden T, Tran HT, Beck D, et al. Novel marine-derived anticancer agents: a phase I clinical pharmacological, and pharmacodynamic study of dolastatin 10 (NSC 376128) in patients with advanced solid tumors. Clin Cancer Res 2000;6:1293-301.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1293-1301
-
-
Madden, T.1
Tran, H.T.2
Beck, D.3
-
8
-
-
0024536437
-
Optimal two-stage designs for phase II clinical trials
-
Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials 1989;10:1-10.
-
(1989)
Control Clin Trials
, vol.10
, pp. 1-10
-
-
Simon, R.1
-
9
-
-
0034093431
-
Phase II study of dolastatin-10 in patients with advanced non-small-cell lung cancer
-
Krug LM, Miller VA, Kalemkerian GP, et al. Phase II study of dolastatin-10 in patients with advanced non-small-cell lung cancer. Ann Oncol 2000;11:227-8.
-
(2000)
Ann Oncol
, vol.11
, pp. 227-228
-
-
Krug, L.M.1
Miller, V.A.2
Kalemkerian, G.P.3
-
10
-
-
45349103120
-
Dolastatin-10 (DOLA) in metastatic melanoma (MEL): A phase II trial of the California Cancer Consortium
-
Margolin KA, Longmage J, Gandara DR, et al. Dolastatin-10 (DOLA) in metastatic melanoma (MEL): a phase II trial of the California Cancer Consortium [Abstract 2243]. Proc Am Soc Clin Oncol 2000;19:569a.
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Margolin, K.A.1
Longmage, J.2
Gandara, D.R.3
-
11
-
-
4243544685
-
Dolastatin 10 (dola 10) administered with G-CSF allows substantial escalation of the maximum tolerated dose (MTD) in patients (pts) with advanced solid tumors
-
Madden T, Tran HT, Felix E, et al. Dolastatin 10 (dola 10) administered with G-CSF allows substantial escalation of the maximum tolerated dose (MTD) in patients (pts) with advanced solid tumors [Abstract 300]. Clin Cancer Res 1999;5(suppl):3789S.
-
(1999)
Clin Cancer Res
, vol.5
, Issue.SUPPL.
-
-
Madden, T.1
Tran, H.T.2
Felix, E.3
|