Accelerated hyperfractionated radiotherapy and concurrent protracted venous infusion chemotherapy in locally advanced head and neck cancer

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 25, Issue 5, 2002, Pages 431-437

  Arcangeli, Giorgio ^a   Saracino, Biancamaria ^a   Tirindelli Danesi, Donatella ^a   De Campora, Enrico ^a   Giovinazzo, Giuseppe ^a   Cognetti, Francesco ^a   Carlini, Paolo ^a   Arcangeli, Stefano ^a   Mecozzi, Antonella ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Concomitant radiotherapy and chemotherapy; Head and neck cancer; Larynx preservation

Indexed keywords

CISPLATIN; FLUOROURACIL;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BONE MARROW TOXICITY; CACHEXIA; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; DISSEMINATED INTRAVASCULAR CLOTTING; FEMALE; FOLLOW UP; HEAD AND NECK CANCER; HUMAN; HYPOPHARYNX CANCER; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; MOTOR NEUROPATHY; MUCOSA INFLAMMATION; POSTOPERATIVE CARE; RADIATION DOSE; SENSORY NEUROPATHY; SKIN FIBROSIS; SURVIVAL TIME;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; COMBINED MODALITY THERAPY; DOSE FRACTIONATION; FEMALE; FLUOROURACIL; HEAD AND NECK NEOPLASMS; HUMANS; INFUSION PUMPS, IMPLANTABLE; INFUSIONS, INTRAVENOUS; LARYNGEAL NEOPLASMS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; PHARYNGEAL NEOPLASMS; PILOT PROJECTS; SURVIVAL ANALYSIS;

EID: 0036794924     PISSN: 02773732     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000421-200210000-00001     Document Type: Article

References (39)

1. Zanetti R, Crosignani P, Rosso S. Cancer in Italy. Vol. 2. Rome: II Pensiero Scientifico Editore, 1997.
2. Arcangeli G, Nervi C, Righini R, et al. Combined radiation and drugs: the effect of intra-arterial chemotherapy followed by radiotherapy in head and neck cancer. Radiother Oncol 1983;1:101-7.
3. Head and Neck Contracts Program. Adjuvant chemotherapy for advanced head and neck squamous carcinoma. Cancer 1987;60:301-11.
4. Lewin F, Damber L, Jonsson H, et al. Neoadjuvant chemotherapy with cisplatin and 5-fluorouracil in advanced squamous cell carcinoma of the head and neck: a randomized Phase III study. Radiother Oncol 1997;43:23-8.
5. Pignon JP, Bourhis J, Domenge C, et al. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. Lancet 2000;355:949-55.
6. Schuller DE, Metch B, Mattox D, et al. Preoperative chemotherapy in advanced resectable head and neck cancer: final report of the Southwest Oncology Group. Laryngoscope 1985;98:1205-11.
7. Toohill RJ, Duncavage JA, Malin TC, et al. The effects of delay in standard treatment due to induction chemotherapy in two randomized prospective studies. Laryngoscope 1987;97:407-12.
8. Byfield JE, Calabro-Jones P, Klisak I, et al. Pharmacologic requirements for obtaining sensitization of human tumors cells in vitro to combined 5-fluorouracil or ftorafur and x-rays. Int J Radiat Oncol Biol Phys 1982;8:1923-33.
9. Vietti T, Eggerding F, Valeriote F. Combined effect of x-radiation and 5-fluorouracil on survival of transplanted leukemic cells. J Natl Cancer Inst 1971;47:865-70.
10. Dewit L. Combined treatment with radiation and cisdiamminedichloroplatinum (II): a review of experimental and clinical data. Int J Radiat Oncol Biol Phys 1987;13:403-26.
11. Douple EB. Platinum-radiation interactions. Natl Cancer Inst Monogr 1988;6:315-9.
12. Hong WK, Bromer R. Chemotherapy in head and neck cancer. N Engl J Med 1983;308:75-9.
13. Fu KK, Phillips TL, Silverberg IV, et al. Combined radiotherapy and chemotherapy with bleomycin and methotrexate for advanced inoperable head and neck cancer: update of a Northern California Oncology Group randomized trial. J Clin Oncol 1987;5:1410-8.
14. Lo TC, Wiley AL Jr, Ansfield FJ, et al. Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of the oral cavity and oropharynx: a randomized study. Am J Roentgenol 1976;126:229-35.
15. Shanta V, Krishnamurthi S. Combined bleomycin and radiotherapy in oral cancer. Clin Radiol 1980;31:617-20.
16. Weissberg JB, Son YH, Papac RJ, et al. Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer. Int J Radiat Oncol Biol Phys 1989;17:3-9.
17. Haselow RE, Warshaw MG, Oken MM, et al. Radiation alone versus radiation with weekly low dose cisplatinum in unresectable cancer of the head and neck. Head Neck Cancer 1990;2:279-81.
18. Jeremic B, Shibamoto Y, Milic B, et al. Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: a prospective randomized trial. J Clin Oncol 2000;18:1458-64.
19. Adelstein DJ, Kalish LA, Adams GL, et al. Concurrent radiation therapy and chemotherapy for locally unresectable squamous cell head and neck cancer: an Eastern Cooperative Oncology Group pilot study. J Clin Oncol 1993;11:2136-42.
20. Taylor SG IV, Murthy AK, Caldarelli DD, et al. Combined simultaneous cisplatin/fluorouracil chemotherapy and split course radiation in head and neck cancer. J Clin Oncol 1989;7:846-56.
21. Vokes EE, Kies M, Haraf DJ, et al. Induction chemotherapy followed by concomitant chemoradiotherapy for advanced head and neck cancer: impact on the natural history of the disease. J Clin Oncol 1995;13:876-83.
22. Wendt TG, Hartenstein RC, Wustrow TP, et al. Cisplatin, fluorouracil with leucovorin enhancement, and synchronous accelerated radiotherapy in the management of locally advanced head and neck cancer. A phase II study. J Clin Oncol 1989;7:471-8.
23. Rosenthal CJ, Rotman M, Choi K, et al. Cisplatin by concurrent radiation in malignant tumors (A phase I-II study). In: Rosenthal CJ, Rothman M, eds. Clinical application of continuous infusion chemotherapy and concomitant radiation therapy. New York: Plenum Press, 1986:177-80.
24. Tirindelli Danesi D, Arcangeli G, Cruciani E, et al. Combined treatment of invasive bladder carcinoma with transurethral resection, induction chemotherapy, and radical radiotherapy plus concomitant protracted infusion of cisplatin and 5-fluorouracil. Cancer 1997;80:1464-71.
25. Kaplan EL, Meier P. Nonparametric estimation for incomplete observations. J Am Stat Assoc 1958;53:457-81.
26. Chemon GH, Bastz L, Hoffman HT, et al. Neurotoxicity in a phase I trial of continuous infusion cisplatin with hyperfractionated radiotherapy for locally advanced head and neck cancer. Head Neck 1996;18:236-41.
27. Department of Veterans Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med 1991;324:1685-90.
28. Mead GM, Jacobs C. Changing role of chemotherapy in treatment of head and neck cancer. Am J Med 1982;73:582-95.
29. Tannock IF. Combined modality treatment with radiotherapy and chemotherapy. Radiother Oncol 1989;16:83-101.
30. Withers HR, Taylor JMF, Maciejewski B. The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncol 1988;27:131-46.
31. Weppelmann B, Wheeler RH, Peters GE, et al. A phase I study of prolonged infusion 5-fluorouracil and concomitant radiation therapy in patients with squamous cell cancer of the head and neck. Int J Radiat Oncol Biol Phys 1991;20:357-60.
32. Marcial VA, Pajak TF. Radiation therapy alone or in combination with surgery in head and neck cancer. Cancer 1985;55:2259-65.
33. Rentschler RE, Wilbur DW, Petti GH, et al. Adjuvant methotrexate escalated to toxicity for resectable stage III and IV squamous head and neck carcinomas-a prospective, randomized study. J Clin Oncol 1987;5:278-85.
34. Taylor SG IV, Applebaum E, Showel JL, et al. A randomized trial of adjuvant chemotherapy in head and neck cancer. J Clin Oncol 1985;3:672-9.
35. Demard F, Chauvel P, Santini J, et al. Response to chemotherapy as justification for modification of the therapeutic strategy for pharyngolaryngeal carcinoma. Head Neck 1990;12:225-31.
36. Hirsch SM, Caldarelli DD, Hutchinson JC, et al. Concomitant chemotherapy and split-course radiation for cure and preservation of speech and swallowing in head and neck cancer. Laryngoscope 1991;101:583-6.
37. Jacobs C, Goffinet DR, Goffinet L, et al. Chemotherapy as a substitute for surgery in the treatment of advanced resectable head and neck cancer: a report from the Northern California Oncology Group. Cancer 1987;60:1178-83.
38. Karp DD, Vaughan CW, Carter R, et al. Larynx preservation using induction chemotherapy plus radiation therapy as an alternative to laryngectomy in advanced head and neck cancer. Am J Clin Oncol 1991;14:273-9.
39. Pfister DG, Strong EW, Harrison L, et al. Larynx preservation with combined chemotherapy and radiation therapy in advanced but resectable head and neck cancer. J Clin Oncol 1991;9:850-9.