Aromatase P450 messenger RNA expression in eutopic endometrium is not a specific marker for pelvic endometriosis

Fertility and Sterility

Volumn 78, Issue 4, 2002, Pages 825-829

  Dheenadayalu, Kavitha ^a   Mak, Ian ^b   Gordts, Stephan ^c   Campo, Rudi ^c   Higham, Jenny ^d   Puttemans, Patrick ^e   White, John ^b   Christian, Mark ^b   Fusi, Luca ^a   Brosens, Jan ^a,b  

^a EALING HOSPITAL   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c LEUVEN INSTITUTE FOR FERTILITY AND EMBRYOLOGY   (Belgium)

^d ST MARY S HOSPITAL   (United Kingdom)

^e Brussels Saint Elisabeth Clinic   (Belgium)

Author keywords

Aromatase; Diagnosis; Endometriosis; Endometrium; mRNA

Indexed keywords

AROMATASE; BIOLOGICAL MARKER; CYTOCHROME P450; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA;

ADULT; CONFERENCE PAPER; CONTROLLED STUDY; ENDOMETRIOSIS; ENDOMETRIUM; ENDOMETRIUM BIOPSY; FEMALE; FEMALE STERILITY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INCIDENCE; LAPAROSCOPY; MAJOR CLINICAL STUDY; PAIN ASSESSMENT; PATHOLOGY; PREDICTION; PRIORITY JOURNAL; REPRODUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SUBFERTILITY;

ADULT; AROMATASE; BIOLOGICAL MARKERS; BIOPSY; ENDOMETRIOSIS; ENDOMETRIUM; FALSE NEGATIVE REACTIONS; FEMALE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; LAPAROSCOPY; MIDDLE AGED; PROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY;

EID: 0036790794     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(02)03324-1     Document Type: Conference Paper

References (29)

1. Brosens I.A., Koninckx P.R., Corveleyn P.A. A study of plasma progesterone, oestradiol-17beta, prolactin and LH levels, and of the luteal phase appearance of the ovaries in patients with endometriosis and infertility. Br J Obstet Gynaecol. 85:1978;246-250.
2. Cahill D.J., Wardle P.G., Maile L.A., Harlow C.R., Hull M.G. Ovarian dysfunction in endometriosis-associated and unexplained infertility. J Assist Reprod Genet. 14:1997;554-557.
3. Kaya H., Oral B. Effect of ovarian involvement on the frequency of luteinized unruptured follicle in endometriosis. Gynecol Obstet Invest. 48:1999;123-126.
4. Brosens I.A., Brosens J.J. Redefining endometriosis is deep endometriosis a progressive disease? Hum Reprod. 15:2000;1-3.
5. Taylor H.S., Bagot C., Kardana A., Olive D., Arici A. HOX gene expression is altered in the endometrium of women with endometriosis. Hum Reprod. 14:1999;1328-1331.
6. Kunz G., Beil D., Huppert P., Leyendecker G. Structural abnormalities of the uterine wall in women with endometriosis and infertility visualized by vaginal sonography and magnetic resonance imaging. Hum Reprod. 15:2000;76-82.
7. Leyendecker G., Kunz G., Wildt L., Beil D., Deininger H. Uterine hyperperistalsis and dysperistalsis as dysfunctions of the mechanism of rapid sperm transport in patients with endometriosis and infertility. Hum Reprod. 11:1996;1542-1551.
8. Dechaud H., Maudelonde T., Daures J.P., Rossi J.F., Hedon B. Evaluation of endometrial inflammation by quantification of macrophages, T lymphocytes, and interleukin-1 and -6 in human endometrium. J Assist Reprod Genet. 15:1998;612-618.
9. Ota H., Igarashi S., Tanaka T. Expression of gamma delta T cells and adhesion molecules in endometriotic tissue in patients with endometriosis and adenomyosis. Am J Reprod Immunol. 35:1996;477-482.
10. Bergqvist A., Bruse C., Carlberg M., Carlstrom K. Interleukin 1beta, interleukin-6, and tumor necrosis factor-alpha in endometriotic tissue and in endometrium. Fertil Steril. 75:2001;489-495.
11. Tseng J.F., Ryan I.P., Milam T.D., Murai J.T., Schriock E.D., Landers D.V., et al. Interleukin-6 secretion in vitro is up-regulated in ectopic and eutopic endometrial stromal cells from women with endometriosis. J Clin Endocrinol Metab. 81:1996;1118-1122.
12. Ota H., Tanaka T. Integrin adhesion molecules in the endometrial glandular epithelium in patients with endometriosis or adenomyosis. J Obstet Gynaecol Res. 23:1997;485-491.
13. Kitawaki J., Noguchi T., Amatsu T., Maeda K., Tsukamoto K., Yamamoto T., et al. Expression of aromatase cytochrome P450 protein and messenger ribonucleic acid in human endometriotic and adenomyotic tissues but not in normal endometrium. Biol Reprod. 57:1997;514-519.
14. Kitawaki J., Kusuki I., Koshiba H., Tsukamoto K., Fushiki S., Honjo H. Detection of aromatase cytochrome P-450 in endometrial biopsy specimens as a diagnostic test for endometriosis. Fertil Steril. 72:1999;1100-1106.
15. Kitawaki J., Koshiba H., Ishihara H., Kusuki I., Tsukamoto K., Honjo H. Progesterone induction of 17beta-hydroxysteroid dehydrogenase type 2 during the secretory phase occurs in the endometrium of estrogen-dependent benign diseases but not in normal endometrium. J Clin Endocrinol Metab. 85:2000;3292-3296.
16. Noble L.S., Simpson E.R., Johns A., Bulun S.E. Aromatase expression in endometriosis. J Clin Endocrinol Metab. 81:1996;174-179.
17. Zeitoun K., Takayama K., Michael M.D., Bulun S.E. Stimulation of aromatase P450 promoter (II) activity in endometriosis and its inhibition in endometrium are regulated by competitive binding of steroidogenic factor-1 and chicken ovalbumin upstream promoter transcription factor to the same cis-acting element. Mol Endocrinol. 13:1999;239-253.
18. Sumitani H., Shozu M., Segawa T., Murakami K., Yang H.J., Shimada K., et al. In situ estrogen synthesized by aromatase P450 in uterine leiomyoma cells promotes cell growth probably via an autocrine/intracrine mechanism. Endocrinology. 141:2000;3852-3861.
19. Yamaki J., Yamamoto T., Okada H. Aromatization of androstenedione by normal and neoplastic endometrium of the uterus. J Steroid Biochem. 22:1985;63-66.
20. Yamamoto T., Noguchi T., Tamura T., Kitawaki J., Okada H. Evidence for estrogen synthesis in adenomyotic tissues. Am J Obstet Gynecol. 169:1993;734-738.
21. Revised American Fertility Society . Classification of endometriosis 1985 . Fertil Steril. 43:1985;351-352.
22. Stempel L.E. Eenie, meenie, minie, mo. What do the data really show? Am J Obstet Gynecol. 144:1982;745-752.
23. Vasquez G., Cornillie F., Brosens I.A. Peritoneal endometriosis scanning electron microscopy and histology of minimal pelvic endometriotic lesions . Fertil Steril. 42:1984;696-703.
24. Wiegerinck M.A., Van Dop P.A., Brosens I.A. The staging of peritoneal endometriosis by the type of active lesion in addition to the revised American Fertility Society classification. Fertil Steril. 60:1993;461-464.
25. Harrison R.F., Barry-Kinsella C. Efficacy of medroxyprogesterone treatment in infertile women with endometriosis a prospective, randomized, placebo-controlled study . Fertil Steril. 74:2000;24-30.
26. Brosens J., Brosens I.A. Adenomyosis uteri. Cameron I., Fraser I., Smith S., Clinical disorders of the endometrium and menstrual cycle. 1998;297-312 Oxford University Press, Oxford.
27. Zeitoun K.M., Bulun S.E. Aromatase a key molecule in the pathophysiology of endometriosis and a therapeutic target . Fertil Steril. 72:1999;961-969.
28. Campbell I.G., Thomas E.J. Endometriosis candidate genes . Hum Reprod Update. 7:2001;15-20.
29. Bischoff F.Z., Simpson J.L. Heritability and molecular genetic studies of endometriosis. Hum Reprod Update. 6:2000;37-44.