Neuronal degradation in mouse retina after a transient ischemia and protective effect of hypothermia

Neurological Research

Volumn 24, Issue 7, 2002, Pages 730-735

  Wang, Xiaodan ^a   Niwa, Masayuki ^a   Hara, Akira ^a   Matsuno, Hiroyuki ^a   Kawase, Kazuhide ^a   Kozawa, Osamu ^a   Mori, Hideki ^a   Uematsu, Toshihiko ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Hypothermia; Ischemia; Neuronal death; Retina

Indexed keywords

DNA FRAGMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CELL PROTECTION; CONTROLLED STUDY; HISTOPATHOLOGY; INDUCED HYPOTHERMIA; INTRAOCULAR PRESSURE; INTRAOCULAR PRESSURE ABNORMALITY; LOW TEMPERATURE; MALE; MOUSE; NERVE CELL NECROSIS; NICK END LABELING; NONHUMAN; REPERFUSION; RETINA; RETINA BIPOLAR GANGLION CELL; RETINA ISCHEMIA; RETINA NERVE CELL; TEMPERATURE SENSITIVITY; TISSUE REACTION;

ANIMALS; BODY TEMPERATURE; BRAIN ISCHEMIA; CELL DEATH; DISEASE MODELS, ANIMAL; HYPOTHERMIA, INDUCED; IN SITU NICK-END LABELING; MALE; MICE; NERVE DEGENERATION; PHOTORECEPTORS; REPERFUSION INJURY; RETINAL DEGENERATION; RETINAL GANGLION CELLS; TREATMENT OUTCOME;

EID: 0036789392     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164102101200663     Document Type: Article

References (27)

1. Smith W, Assink J, Klein R, Mitchell P, Klaver CC, Klein BE, Hofman A, Jensen S, Wang JJ, de Jong PT. Risk factors for age-related muscular degeneration. Pooled findings from three continents. Ophthalmology 2001; 108: 697-704
2. Daugeliene L, Niwa M, Hara A, Matsuno H, Yamamoto T, Kitazawa Y, Uematsu T. Transient ischemic injury in the rat retina caused by thrombotic occlusion-thrombolytic reperfusion. Invest Ophthalmol Vis Sci 2000; 41: 2743-2747
3. Joo CK, Choi JS, Ko HW, Park KY, Sohn S, Chun MH, Oh YJ, Gwag BJ. Necrosis and apoptosis after retinal ischemia: Involvement of NMDA-mediated excitotoxicity and p53. Invest Ophthalmol Vis Sci 1999; 40: 713-720
4. Arends MJ, Morris RG, Wyllie AH. Apoptosis. The role of the endonuclease. Am J Pathol 1990; 36: 593-608
5. Niwa M, Hara A, Iwai T, Nakashima M, Yano H, Yoshimi N, Mori H, Uematsu T. Relationship between magnitude of hypothermia during ischemia and preventive effect against post-ischemic DNA fragmentation in the gerbil hippocampus. Brain Res 1998; 794: 338-342
6. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 19: 493-501
7. Yamaguchi M, Imai M, Ohashi H. Enhanced myocardial protection by systemic deep hypothermia in children undergoing total correction of tetralogy of fallot. Ann Thorac Surg 1986; 41: 639
8. Lougheed WM, Sweet WH, White JC, Brewater WR. The use of hypothermia in surgical treatment of cerebral vascular lesions. J Neurosurg 1995; 12: 240-255
9. Hara A, Niwa M, Iwai T, Nakashima M, Bunai Y, Uematsu T, Yoshimi N, Mori H. Neuronal apoptosis studied by a sequential TUNEL technique: A method for tract-tracing. Brain Res Protoc 1999; 4: 140-146
10. Rinknoff J, Machemer R, Hida T, Chandler D. Temperature- dependent light damage to the retina. Am J Ophthalmol 1986; 102: 452-462
11. Kaibara T, Sutherland GR, Colbourne F, Tyson RI. Hypothermia: Depression of tricarboxylic acid cycle flux and evidence for pentose phosphate shunt upregulation. J Neurosurg 1999; 90: 339-347
12. Lo EK, Steinberg GK. Effects of hypothermia on evoked potentials, magnetic resonance imaging, and blood flow in focal ischemia in rabbits. Stroke 1992; 23: 889-893
13. Tamai K, Toumoto E, Majima A. Local hypothermia protects the retina from ischaemic injury in vitrectomy. Br J Ophthalmol 1997; 81: 789-794
14. Busto R, Clobus MY, Dietrich WD, Marthnez E, Valdes I. Effect of mild hypothermia on ischemia-induced release of neurotransmitter and free fatty acid in rat brain. Stroke 1989; 20: 904-910
15. Chopp M, Knight R, Tidwell CD. The metabolic effects of mild hypothermia on global cerebral ischemia and recirculation in cat: Comparison to normothermia and hyperthermia. J Cereb Blood Flow Metab 1989; 9: 141-148
16. Kim IB, Kim KY, Joo CK, Lee MY, Oh SJ, Chung JW, Chun MH. Reaction of Muller cells after increased intraocular pressure in the rat retina. Exp Brain Res 1998; 121: 419-424
17. Cardell M, Boris-Moller F, Wieloch T. Hypothermia prevents the ischemia-induced translocation and inhibition of protein kinase C in the rat striatum. J Neurochem 1991; 57: 1814-1817
18. Kermer P, Ankerhold R, Klocker N, Krajewski S. Caspase-9: Involvement in secondary death of axotomized rat retina ganglion cells in vivo. Brain Res Mol Brain Res 2000; 85: 144-150
19. Klocker N, Kermer P, Weishaupt JH, Labes M, Ankerhold R, Bahr M. Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3′-kinase/protein kinase B signaling. J Neurosci 2000; 20: 6962-6967
20. Seigel GM, Chui L, Paxhia A. Inhibition of neuroretinal cell death by insulin-like growth factor-1 and its analogs. Mol Vis 2000; 6: 157-163
21. D'Cruz BJ, Fertig KC, Filiano AJ, Hicks SD, DeFranco DB, Callaway CW. Hypothermia increases brain-derived neurotrophic factor levels in post-ischemia brain. Acad Emerg Med 2001; 8: 511-512
22. Rosenbaum DM, Rosenbaum PS, Gupta H, Singh M, Aggarwal A, Hall DH, Roth S, Kessler JA. The role of the p53 protein in the selective vulnerability of the inner retina to transient ischemia. Invest Ophthalmol Vis Sci 1998; 39: 2132-2139
23. Szabo ME, Droy LeFair MT, Doly M, Carre C, Braquet P. Ischemia and reperfusion-induced histologic changes in the rat retina. Invest Ophthalmol Vis Sci 1991; 32: 1471-1478
24. Hayreh SS, Weingeist TA. Experimental occlusion of the central artery of the retina. IV. Retinal tolerance time to acute ischemia. Br J Ophthalmol 1980; 64: 818-825
25. Ju WK, Kim KY, Hofmann HD, Kim IB, Lee MY, Oh SJ, Chun MH. Selective neuronal survival and upregulation of PCNA in the rat inner retina following transient ischemia. J Neuropathol Exp Neurol 2000; 59: 241-250
26. Donello JE, Padillo EU, Webster ML, Wheeler LA, Gil DW. Alpha(2)-adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia. J Pharmacol Exp Ther 2001; 296: 216-223
27. Devadas M, Sugawara K, Shimada Y, Sugitani K, Liu ZW, Matsukawa T, Kato S. Slow recovery of goldfish retinal ganglion cells' soma size during regeneration. Neurosci Res 2000; 37: 289-297