Adequacy of antidepressant treatment after discharge and the occurrence of suicidal acts in major depression: A prospective study

American Journal of Psychiatry

Volumn 159, Issue 10, 2002, Pages 1746-1751

  Oquendo, Maria A ^a   Kamali, Masoud ^a   Ellis, Steven P ^a   Grunebaum, Michael F ^a   Malone, Kevin M ^a   Brodsky, Beth S ^a   Sackeim, Harold A ^a   Mann, J John ^a  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; DESIPRAMINE; DOXEPIN; FLUOXETINE; FLUVOXAMINE; IMIPRAMINE; ISOCARBOXAZID; LITHIUM; MAPROTILINE; MIRTAZAPINE; MOCLOBEMIDE; NEFAZODONE; NOMIFENSINE; NORTRIPTYLINE; PAROXETINE; PHENELZINE; PROTRIPTYLINE; SELEGILINE; SERTRALINE; TRANYLCYPROMINE; TRAZODONE; TRIMIPRAMINE; VENLAFAXINE;

ADULT; AGED; ANAMNESIS; ARTICLE; CONTROLLED STUDY; COVARIANCE; DISEASE ASSOCIATION; DRUG EFFICACY; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SUICIDE; SUICIDE ATTEMPT; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AFTERCARE; AGE FACTORS; AGED; ANTIDEPRESSIVE AGENTS; DEPRESSIVE DISORDER; FEMALE; FOLLOW-UP STUDIES; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK FACTORS; SUICIDE; SUICIDE, ATTEMPTED; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 0036787399     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.159.10.1746     Document Type: Article

References (48)

1. Chen Y-W, Dilsaver SC: Lifetime rates of suicide attempts among subjects with bipolar and unipolar disorders relative to subjects with other axis I disorders. Biol Psychiatry 1996; 39: 896-899
2. Barraclough B, Bunch J, Nelson B, Sainsbury P: One hundred cases of suicide: clinical aspects. Eur J Psychiatry 1974; 125:355-373
3. Dorpat TL, Ripley HS: A study of suicide in the Seattle area. Compr Psychiatry 1960; 1:349-359
4. Carlson GA, Rich CL, Grayson P, Fowler RC: Secular trends in psychiatric diagnoses of suicide victims. J Affect Disord 1991; 21:127-132
5. Henriksson MM, Aro HM, Marttunen MJ, Heikkinen ME, Isometsä ET, Kuoppasalmi KI, Lönnqvist JK: Mental disorders and comorbidity in suicide. Am J Psychiatry 1993; 150:935-940
6. Hagnell O, Rorsman B: Suicide in the Lundby study: a comparative investigation of clinical aspects. Neuropsychobiology 1979; 5:61-73
7. Black DW, Winokur G: Prospective studies of suicide and mortality in psychiatric patients. Ann NY Acad Sci 1986; 487:107-113
8. Fawcett J, Scheftner W, Clark D, Fledeker D, Gibbons R, Coryell W: Clinical predictors of suicide in patients with major affective disorders: a controlled prospective study. Am J Psychiatry 1987; 144:35-40
9. Berglund M, Nilsson K: Mortality in severe depression: a prospective study including 103 suicides. Acta Psychiatr Scand 1987; 76:372-380
10. Borg SE, Stahl M: Prediction of suicide: a prospective study of suicides and controls among psychiatric patients. Acta Psychiatr Scand 1982; 65:221-232
11. Dorpat TL, Ripley HS: The relationship between attempted suicide and committed suicide. Compr Psychiatry 1967; 8:74-79
12. Nordström P, Åsberg M, Aberg-Wistedt A, Nordin C: Attempted suicide predicts suicide risk in mood disorders. Acta Psychiatr Scand 1995; 92:345-350
13. Duggan CF, Sham P, Lee AS, Murray RM: Can future suicidal behaviour in depressed patients be predicted? J Affect Disord 1991; 22:111-118
14. Bostwick JM, Pankratz VS: Affective disorders and suicide risk: a reexamination. Am J Psychiatry 2000; 157:1925-1932
15. Fawcett J, Scheftner WA, Fogg L, Clark DC, Young MA, Hedeker D, Gibbons R: Time-related predictors of suicide in major affective disorder. Am J Psychiatry 1990; 147:1189-1194
16. Brådvik L, Berglund M: Risk factors for suicide in melancholia: a case-record evaluation of 89 suicides and their controls. Acta Psychiatr Scand 1993; 87:306-311
17. Bille-Brahe U, Kerkhof A, De Leo D, Schmidtke A, Crepet P, Lönnqvist J, Michel K, Salander-Renberg E, Stiles TC, Wasserman D, Aagaard B, Egebo H, Jensen B: A repetition-prediction study of European parasuicide populations: a summary of the first report from part II of the WHO/EURO Multicentre Study on Parasuicide in cooperation with the EC Concerted Action on Attempted Suicide. Acta Psychiatr Scand 1997; 95:81-86
18. Spitzer RL, Williams JBW, Gibbon M, First MB: Structured Clinical Interview for DSM-III-R - Patient Version 1.0 (SCID-P). Washington, DC, American Psychiatric Press, 1990
19. Oquendo MA, Halberstam B, Mann JJ: Risk factors for suicidal behavior: the utility and limitations of research instruments, in Standardized Assessment for the Clinician. Edited by First MB, (Review of Psychiatry, vol 22, Oldham JM, Riba MB, series editors). Washington, DC, American Psychiatric Press (in press)
20. Beck AT, Kovacs M, Weissman A: Assessment of suicidal intention: the Scale for Suicide Ideation. J Consult Clin Psychol 1979; 47:343-352
21. Hamilton M: A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62
22. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J: An inventory for measuring depression. Arch Gen Psychiatry 1961; 4: 561-571
23. Loranger AW, Susman VL, Oldham JM, Russakoff LM: The Personality Disorder Examination: a preliminary report. J Personal Disord 1987; 1:1-13
24. First MB, Gibbon M, Spitzer RL, Williams JB: Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II), version 2. New York, New York Psychiatric Institute, Biometrics Research, 1996
25. Sackeim HA, Prudic J, Devanand DP, Decina P, Kerr B, Malitz S: The impact of medication resistance and continuation pharmacotherapy on relapse following response to electroconvulsive therapy in major depression. J Clin Psychopharmacol 1990; 10:96-104
26. Prudic J, Haskett RF, Mulsant B, Malone KM, Pettinati HM, Stephens S, Greenberg R, Rifas SL, Sackeim HA: Resistance to antidepressant medications and short-term clinical response to ECT. Am J Psychiatry 1996; 153:985-992
27. Oquendo MA, Malone KM, Mann JJ: Suicide: risk factors and prevention in refractory major depression. Depress Anxiety 1997; 5:202-211
28. Montgomery SA, Dunner DL, Dunbar GC: Reduction of suicidal thoughts with paroxetine in comparison with reference antidepressants and placebo. Eur Neuropsychopharmacol 1995; 5:5-13
29. Leon AC, Keller MB, Warshaw MG, Mueller TI, Solomon DA, Coryell W, Endicott J: Prospective study of fluoxetine treatment and suicidal behavior in affectively ill subjects. Am J Psychiatry 1999; 156:195-201
30. Khan A, Warner HA, Brown WA: Symptom reduction and suicide risk in patients treated with placebo in antidepressant clinical trials: an analysis of the Food and Drug Administration database. Arch Gen Psychiatry 2000; 57:311-317
31. Modestin J, Schwarzenbach F: Effect of psychopharmacotherapy on suicide risk in discharged psychiatric inpatients. Acta Psychiatr Scand 1992; 85:173-175
32. Müller-Oerlinghausen B, Müser-Causemann B, Volk J: Suicides and parasuicides in a high-risk patient group on and off lithium long-term medication. J Affect Disord 1992; 225:261-270
33. Tondo L, Baldessarini RJ, Hennen J, Floris G, Silvetti F, Tohen M: Lithium treatment and risk of suicidal behavior in bipolar disorder patients. J Clin Psychiatry 1998; 59:405-414
34. Kallner G, Lindelius R, Petterson U, Stockman O, Tham A: Mortality in 497 patients with affective disorders attending a lithium clinic or after having left it. Pharmacopsychiatry 2000; 33:8-13
35. Rihmer Z, Barsi J, Veg K, Katona CLE: Suicide rates in Hungary correlate negatively with reported rates of depression. J Affect Disord 1990; 20:87-91
36. Isacsson G, Bergman U, Rich CL: Epidemiological data suggest antidepressants reduce suicide risk among depressives. J Affect Disord 1996; 41:1-8
37. Rutz W, Von Knorring L, Walinder J: Long-term effects of an educational program for general practitioners given by the Swedish Committee for the Prevention and Treatment of Depression. Acta Psychiatr Scand 1992; 85:83-88
38. Isacsson G, Holmgren P, Druid H, Bergman U: Psychotropics and suicide prevention: implications from toxicological screening of 5,281 suicides in Sweden 1992-1994. Br J Psychiatry 1999; 174:259-265
39. Isacsson G, Bergman U, Rich CL: Antidepressants, depression and suicide: an analysis of the San Diego study. J Affect Disord 1994; 32:277-286
40. Isometsä ET, Henriksson MM, Aro HM, Heikkinen ME, Kuoppasalmi KI, Lönnqvist JK: Suicide in major depression. Am J Psychiatry 1994; 151:530-536
41. Keller MB, Lavori PW, Klerman GL, Andreasen NC, Endicott J, Coryell W, Fawcett J, Rice JP, Hirschfeld RM: Low levels and lack of predictors of somatotherapy and psychotherapy received by depressed patients. Arch Gen Psychiatry 1986; 43:458-466
42. Keller MB, Klerman GL, Lavori PW, Fawcett JA, Coryell W, Endicott J: Treatment received by depressed patients. JAMA 1982; 248:1848-1855
43. Friedman R, Kocsis JH, Chen J-S, Mann JJ: Antidepressant treatment intensity in patients with nonbipolar major depression. Hosp Community Psychiatry 1992; 43:83-84
44. Oquendo MA, Malone KM, Ellis SP, Sackeim HA, Mann JJ: Inadequacy of antidepressant treatment for patients with major depression who are at risk for suicidal behavior. Am J Psychiatry 1999; 156:190-194
45. Sidley GL, Calam R, Wells A, Hughes T, Whitaker K: The prediction of parasuicide repetition in a high-risk group. Br J Clin Psychol 1999; 38:375-386
46. Hirschfeld RMA, Keller M, Panico S, Arons BS, Barlow D, Davidoff F, Endicott J, Froom J, Goldstein M, Gorman JM, Guthrie D, Marek RG, Maurer TA, Meyer R, Philips K, Ross J, Schwenk TL, Sharfstein SS, Thase ME, Wyatt RJ: The National Depressive and Manic-Depressive Association consensus statement on the undertreatment of depression. JAMA 1997; 277:333-340
47. La Vecchia C, Lucchini F, Levi F: Worldwide trends in suicide mortality, 1955-1989. Acta Psychiatr Scand 1994; 90:53-64
48. Isacsson G: Suicide prevention - a medical breakthrough? Acta Psychiatr Scand 2000; 102:113-117