Relaxant mechanisms of parathyroid hormone in rat mesenteric artery

Journal of Cardiovascular Pharmacology

Volumn 40, Issue 4, 2002, Pages 554-563

  Ohta, Toshio ^a   Okamoto, Eri ^a   Shimoya, Machiko ^a   Nakazato, Yoshikazu ^a   Ito, Shigeo ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Fura 2; Nonselective cation channels; Parathyroid hormone; Parathyroid hormone related protein; PTH1 receptor

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; CAFFEINE; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CYCLIC AMP; FURA 2 ACETOXYMETHYL ESTER; GALLOPAMIL; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR; PHENYLEPHRINE; POTASSIUM CHLORIDE; SK AND F 96365; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; HORMONE ACTION; MALE; MESENTERIC ARTERY; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASODILATATION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MESENTERIC ARTERIES; PARATHYROID HORMONE; RATS; RATS, WISTAR; RECEPTORS, PARATHYROID HORMONE; VASOCONSTRICTION; VASODILATION;

EID: 0036784757     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200210000-00008     Document Type: Article

References (35)

1. Charbon GA. A rapid and selective vasodilator effect of parathyroid hormone. Eur J Pharmacol 1968;3:275-8.
2. Nickols GA, Metz MA, Cline WH Jr. Vasodilation of the rat mesenteric vasculature by parathyroid hormone. J Pharmacol Exp Ther 1986;236:419-23.
3. Moseley JM, Kubota M. Diefenbach-Jagger H, et al. Parathyroid hormone-related protein purified from a human lung cancer cell line. Proc Natl Acad Sci U S A 1987;84:5048-52.
4. Philbrick WM, Wysolmerski JJ, Galbraith S, et al. Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol Rev 1996;76:127-91.
5. Abou-Samra AB, Juppner H, Force T, et al. Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci U S A 1992;89:2732-6.
6. Okano K, Wu S, Huang X, et al. Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor and its messenger ribonucleic acid in rat aortic vascular smooth muscle cells and UMR osteoblast-like cells: cell-specific regulation by angiotensin II and PTHrP. Endocrinology 1994;135:1093-9.
7. Hanson AS, Linas SL. Parathyroid hormone/adenylate cyclase coupling in vascular smooth muscle cells. Hypertension 1994;23:468-75.
8. Usdin TB, Bonner TI, Harta G, et al. Distribution of parathyroid hormone-2 receptor messenger ribonucleic acid in rat. Endocrinology 1996;137:4285-97.
9. Behar V, Pines M, Nakamoto C, et al. The human PTH2 receptor: binding and signal transduction properties of the stably expressed recombinant receptor. Endocrinology 1996;137:2748-57.
10. Turner PR, Mefford S, Bambino T, et al. Transmembrane residues together with the amino terminus limit the response of the parathyroid hormone (PTH)-2 receptor to PTH-related peptide. J Biol Chem 1998;273:3830-7.
11. Wang R, Karpinski E, Pang PKT. Parathyroid hormone selectively inhibits L-type calcium channels in single vascular smooth muscle cells of the rat. J Physiol 1991;441: 325-46.
12. Schlüter K-D, Piper HM. Cardiovascular actions of parathyroid hormone and parathyroid hormone-related peptide. Cardiovasc Res 1998;37:34-41.
13. Kuriyama H, Kitamura K, Nabata H. Pharmacological and physiological significance of ion channels and factors that modulate them in vascular tissues. Pharmacol Rev 1995;47:387-573.
14. Wang X, Briner VA, Schrier RW. Parathyroid hormone inhibition of vasopressin-induced vascular smooth muscle contraction. Am J Physiol 1993;264:453-7.
15. Hino T, Nyby MD, Fittingoff M, et al. Parathyroid hormone analogues inhibit calcium mobilization in cultured vascular cells. Hypertension 1994;23:402-8.
16. Jiang B, Morimoto S, Yang J, et al. Expression of parathyroid hormone/parathyroid hormone-related protein receptor in vascular endothelial cells. J Cardiovasc Pharmacol 1998;31(suppl 1):S142-4.
17. Isales CM, Sumpio B, Bollag RJ, et al. Functional parathyroid hormone receptors are present in an umbilical vein endothelial cell line. Am J Physiol 2000;279:E654-62.
18. Katori E, Ohta T, Nakazato Y, et al. Vasopressin-induced contraction in the rat basilar artery in vitro. Eur J Pharmacol 2001;416:113-21.
19. Ohta T, Ito S, Ohga A. Effects of vasoactive intestinal peptide (VIP) on contractile responses of smooth muscle in rat stomach. Br J Pharmacol 1991;102:621-6.
20. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985;260:3440-50.
21. 2+ stores in ileal smooth muscle of the rat. Br J Pharmacol 1995;114:1165-70.
22. Himpes B, Somlyo AP. Free-calcium and force transients during depolarization and pharmacomechanical coupling in guinea-pig smooth muscle. J Physiol 1988;395:507-30.
23. Merritt, JE, Armstrong WP, Benham CD, et al. SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochem J 1990;271:515-22.
24. 2+ release in smooth muscle: physiological role of inositol 1,4,5-trisphosphate in pharmacomechanical coupling. J Biol Chem 1989;264:17997-8004.
25. Iino M. Calcium-induced calcium release mechanism in guinea pig taenia caeci. J Gen Physiol 1989;94:363-83.
26. Jüppner H, Abou-Samra A-B, Freeman M, et al. A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. Science 1991;254:1024-6.
27. Schulze MR, Mügge A, Harms HM, et al. Human parathyroid hormone dilates both pig coronary and human inferior epigastric arteries by a cyclic AMP-dependent pathway. Artery 1993;20:147-62.
28. Zholos AV, Tsytsyura YaD, Philyppov IB, et al. Voltage-dependent inhibition of the muscarinic cationic current in guinea-pig ileal cell by SK&F 96365. Br J Pharmacol 2000;129:695-702.
29. Crass MFd, Scarpace PJ. Vasoactive properties of a parathyroid hormone-related protein in the rat aorta. Peptides 1993;14:179-83.
30. Ishikawa M, Ouchi Y, Akishita M, et al. Age-related decrease in the effect of parathyroid hormone-related protein on cytosolic free calcium level and tension in rat aortic smooth muscle. Naunyn-Schmiedebergs Arch Pharmacol 1995;351:517-22.
31. Xiong Z, Sperelakis N. Regulation of L-type calcium channels of vascular smooth muscle cells. J Mol Cell Cardiol 1995;27:75-91.
32. Savineau JP, Gonzalez De La FP, Marthan R. Effect of vascular smooth muscle relaxants on the protein kinase C-mediated contraction in the rat pulmonary artery. Eur J Pharmacol 1993;249:191-8.
33. Yamagishi T, Yanagisawa T, Satoh K, et al. Relaxant mechanisms of cyclic AMP-increasing agents in porcine coronary artery. Eur J Pharmacol 1994;251:253-62.
34. Ohta T, Ito S, Noto T, et al. The inhibitory action of cyclic AMP on responses to carbachol dependent on calcium stores in rat gastric smooth muscle. J Physiol 1992;453: 367-84.
35. 1-adrenoceptor stimulation are inhibited by forskolin. Eur J Pharmacol 1991;207:29-3.