Persistent hypercholesterolemia is associated with the development of obesity among girls: The Bogalusa Heart Study

American Journal of Clinical Nutrition

Volumn 76, Issue 4, 2002, Pages 730-735

  Tershakovec, Andrew M ^a   Jawad, Abbas F ^a   Stouffer, Nicole O ^a   Elkasabany, Abdalla ^b   Srinivasan, Sathanur R ^b   Berenson, Gerald S ^b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b Tulane Center for Cardiovascular Health   (United States)

Author keywords

Bogalusa Heart Study; Children; Girls; Hypercholesterolemia; Obesity

Indexed keywords

INSULIN; LIPID;

AGE; ARTICLE; BLOOD PRESSURE; BODY MASS; BODY WEIGHT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHILD; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; OBESITY; SEX DIFFERENCE;

EID: 0036784087     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/76.4.730     Document Type: Article

References (54)

1. Webber LS, Voors AW, Srinivasan SR, Frerichs RR, Berenson GS. Occurrence in children of multiple risk factors for coronary artery disease: The Bogalusa Heart Study. Prev Med 1979;8:407-18.
2. Wilmore JH, McNamara JJ. Prevalence of coronary heart disease risk factors in boys, 8 to 12 years of age. J Pediatr 1974;84:527-33.
3. Lauer RM, ConnorWE, Leaverton PE, Reiter MA, Clarke WR. Coronary heart disease risk factors in school children: the Muscatine study. J Pediatr 1975:697-706.
4. Raitakari OT, Porkka KVK, Ronnemaa T, et al. The role of insulin in clustering of serum lipids and blood pressure in children and adolescents. The Cardiovascular Risk in Young Finns Study. Diabetologia 1995;38:1042-50.
5. Guo S, Salisbury S, Roche AF, Chumlea WC, Siervogel RM. Cardiovascular disease risk factors and body composition: a review. Nutr Res 1994;11:1721-77.
6. Chen W, Srinivasan SR, Elkasabany A, Berenson GS. Cardiovascular risk factors clustering features of insulin resistance syndrome (syndrome X) in a biracial (black-white) population of children, adolescents, and young adults: the Bogalusa Heart Study. Am J Epidemiol 1999;150:667-74.
7. Burke GL, Webber LS, Srinivasan SR, Radhakrishnamurthy B, Freedman DS, Berenson GS. Fasting plasma glucose and insulin levels and their relationship to cardiovascular risk factors in children: Bogalusa Heart Study. Metabolism 1986;35:441-6.
8. Jiang X, Srinivasan SR, Webber LS, Wattigney WA, Berenson GS. Association of fasting insulin level with serum lipid and lipoprotein levels in children, adolescents, and young adults: the Bogalusa Heart Study. Arch Intern Med 1995;155:190-6.
9. Walker M. Obesity, insulin resistance, and its link to noninsulin-dependent diabetes mellitus. Metabolism 1995;44:18-20.
10. Kissebah AH, Peiris AN. Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus. Diabetes Metab Rev 1989;15:83-109.
11. Howard BV, Mayer-Davis EJ, Goff D, et al. Relationships between insulin resistance and lipoproteins in nondiabetic African Americans, Hispanics, and non-Hispanic Whites: the Insulin Resistance Atherosclerosis Study. Metabolism 1998;47:1174-9.
12. Blaak EE, Saris WHM, Wolffenbuttel BHR. Substrate utilization and thermogenic responses to β-andrenergic stimulation in obese subjects with NIDDM. Int J Obes Relat Metab Disord 1999;23:411-8.
13. Okosun IS, Cooper RS, Prewitt E, Rotimi CN. The relation of central adiposity to components of the insulin resistance syndrome in a biracial US population sample. Ethnic Dis 1999;9:218-29.
14. Parks EJ, Hellerstein MK. Carbohydrate-induced hypertriacyglycerolemia: historical perspective and review of biological mechanisms. Am J Clin Nutr 2000;71:412-33.
15. Boulton TJC, Johnston O. A coronary risk-factor profile of 4 year olds. II. Inter-relationships, clustering, and tracking of blood pressure, serum lipoproteins, and skinfold thickness. Aust Paediatr J 1978;14:278-82.
16. Smoak CG, Burke GL, Webber LS, Harsha DW, Srinivasan SR, Berenson GS. Relation of obesity to clustering of cardiovascular disease risk factors in children and young adults. The Bogalusa Heart Study. Am J Epidemiol 1987;125:364-72.
17. Jiang X, Srinivasan SR, Urbina E, Berenson GS. Hyperdynamic circulation and cardiovascular risk in children. The Bogalusa Heart Study. Circulation 1995;91:1101-6.
18. Brambilla P, Manzoni P. Sironi S, et al. Peripheral and abdominal adiposity in childhood obesity. Int J Obes Relat Metab Disord 1994;18: 795-800.
19. Caprio S, Hyman LD, McCarthy S, Lange R, Bronson M, Tamborlane WV. Fat distribution and cardiovascular risk factors in obese adolescent girls: importance of the intraabdominal fat depot. Am J Clin Nutr 1996;64:12-7.
20. Monti LD, Brambilla P, Stefani I, et al. Insulin regulation of glucose turnover and lipid levels in obese children with fasting normoinsulinaemia. Diabetologia 1995;38:739-47.
21. Waliu Islam AHM, Yamashita S, Kotani K, et al. Fasting plasma insulin level is an important risk factor for the development of complications in Japanese obese children-results from a cross-sectional and a longitudinal study. Metabolism 1995;4:478-85.
22. Agostoni C, Riva E, Bellu R, Vincenzo SS, Grazia BM, Giovanni M. Relationships between the fatty acid status and insulinemic indexes in obese children. Prostaglandins Leukot Essent Fatty Acids 1994:51: 317-21.
23. Frerichs RR, Webber LS, Srinivasan SR, Berenson GS. Relation of serum lipids and lipoproteins to obesity and sexual maturity in white and black children. Am J Epidemiol 1978;108:486-96.
24. Shear CL, Freedman DS, Burke GL, Harsha DW, Berenson GS. Body fat patterning and blood pressure in children and young adults. The Bogalusa Heart Study. Hypertension 1987;9:236-44.
25. Kikuchi DA, Srinivasan SR, Harsha DW, Webber LS, Sellers TA, Berenson GS. Relation of serum lipoprotein lipids and apolipoproteins to obesity in children: the Bogalusa Heart Study. Prev Med 1992;21:177-90.
26. Zwiauer KFM, Pakosta R, Mueller T, Widhalm K. Cardiovascular risk factors in obese children in relation to weight and body fat distribution. J Am Coll Nutr 1992;11:41S-50S.
27. Ronnemaa T, Knip M, Lautala P, et al. Serum insulin and other cardiovascular risk indicators in children, adolescents and young adults. Ann Med 1991;23:67-72.
28. Le Stunff C, Bougneres P-F. Time course of increased lipid and decreased glucose oxidation during early phase of childhood obesity. Diabetes 1993;42:1010-6.
29. Tershakovec AM, Jawad AF, Stallings VA, Cortner JA, Zemel BS, Shannon BM. Age-related changes in cardiovascular disease risk factors of hypercholesterolemic children. J Pediatr 1998;132:414-20.
30. Berenson GS, McMahan CA, Voors AW, et al. Cardiovascular risk factors in children - the early natural history of atherosclerosis and essential hypertension. New York: Oxford University Press, 1980:1-450.
31. Lipid Research Clinics Program. Manual of laboratory operations. I: Lipid and lipoprotein analysis. Washington, DC: US Government Printing Office, 1974. [DHEW publication (NIH)75-828.]
32. Allain CC, Poon LS, Chan CSG, Richmond W, Wu PC. Enzymatic determination of total serum cholesterol. Clin Chem 1974;20:470-5.
33. Bucolo G, David H. Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem 1973:19:476-82.
34. Srinivasan SR, Berenson GS. Serum lipoprotein in children and methods for study. In: Lewis LA, ed. CRC handbook of electrophoresis. III: Lipoprotein methodology and human studies. Boca Raton, FL: CRC Press, Inc, 1983:185-204.
35. SAS Institute, Inc. SAS release 6.12. Cary, NC: SAS Institute, Inc, 1989-1996.
36. SPSS, Inc. SPSS release 9.0. Chicago: SPSS. Inc. 1980-1999.
37. Centers for Disease Control, National Center for Health Statistics. Individual growth charts. Internet: http://www.cdc.gov/growthcharts (accessed 4 August 2001).
38. Pinhas-Hamiel O, Dolan LM, Daniels SR, Standiford D, Khoury PR, Zeitler P. Increased incidence of non-insulin-dependent diabetes mellitus among adolescents. J Pediatr 1996;128:608-15.
39. Svec F, Nastasi K, Hilson C, Bao W, Srinivasan SR, Berenson GS. Black-white contrasts in insulin levels during pubertal development. The Bogalusa Heart Study. Diabetes 1992;41:313-7.
40. Bao W, Srinivasan SR, Wattigney WA, Bao W, Berenson GS. Usefulness of childhood low-density lipoprotein cholesterol level in predicting adult dyslipidemia and other cardiovascular risks. Arch Intern Med 1996;156:1315-20.
41. Morrison JA, Barton B, Biro FM, Sprecher DL, Falkner F, Obarzanek E. Sexual maturation and obesity in 9- and 10-year-old black and white girls: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr 1994;124:889-95.
42. Shamir R, Tershakovec AM, Gallagher PR, Liacouras CA, Hayman LA, Cortner JA. The influence of age and relative weight on the presentation of familial combined hyperlipidemia in childhood. Atherosclerosis 1996;121:85-91.
43. Karhapaa P, Voutilainen E, Kovanen PT, Laakso M. Insulin resistance in familial and nonfamilial hypercholesterolemia. Arterioscler Thromb 1993;13:41-7.
44. Arslanian S, Suprasongsin C. Differences in the in vivo insulin secretion and sensitivity of healthy black versus white adolescents. J Pediatr 1996;129:440-3.
45. Daniels SR, Obarzanek E, Barton BA, Kimm SYS, Similo SL, Morrison JA. Sexual maturation and racial differences in blood pressure in girls: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr 1996;129:208-13.
46. Craig SB, Bandini LG, Lichtenstein AH, Schaefer EJ, Dietz WH. The impact of physical activity on lipids, lipoproteins, and blood pressure in preadolescent girls. Pediatrics 1996;98:389-95.
47. Travers SH, Jeffers BW, Bloch CA, Hill JO, Eckel RH. Gender and Tanner stage differences in body composition and insulin sensitivity in early pubertal children. J Clin Endocrinol Metab 1995; 80:172-8.
48. Jiang X, Srinivasan SR, Radhakrishnamurthy B, Dalferes ER Jr, Berenson GS. Racial (black-white) differences in insulin secretion and clearance in adolescents: the Bogalusa Heart Study. Pediatrics 1996;97:357-60.
49. Bao W, Srinivasan SR, Berenson GS. Persistent elevation of plasma insulin levels is associated with increased cardiovascular risk in children and young adults: the Bogalusa Heart Study. Circulation 1996; 93:54-9.
50. Braun B, Zimmermann MB, Kretchmer N, Sparago RM, Smith RM, Gracey M. Risk factors for diabetes and cardiovascular disease in young Australian aborigines: a 5-year follow-up study. Diabetes Care 1996;19:472-9.
51. Hoffman RP, Stumbo PJE, Janz KF, Nielsen DH. Altered insulin resistance is associated with increased dietary weight loss in obese children. Horm Res 1995;44:17-22.
52. Freedman DS, William WH, Srinivasan SR, Berenson GS. The relation of overweight to cardiovascular risk factors among children and adolescents: the Bogalusa Heart Study. Pediatrics 1999;103: 1175-82.
53. Dvorak RV, DeNino WF, Ades PA, Poehlman ET. Phenotypic characteristics associated with insulin resistance in metabolically obese but normal weight young women. Diabetes 1999;48:2210-4.
54. Ruderman NB, Schneider SH, Berchtold P. The "metabolically obese," normal weight individual. Am J Clin Nutr 1981;34:1617-21.