Effects of corticosteroids on nerve root recovery after spinal nerve root compression

Clinical Orthopaedics and Related Research

Volumn 403, Issue , 2002, Pages 248-252

  Wong, Hee Kit ^a   Tan, Ken Jin ^a  

^a NATIONAL UNIVERSITY HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; BETAMETHASONE; CD4 ANTIGEN; CD5 ANTIGEN; CORTICOSTEROID; GELFOAM; SODIUM CHLORIDE; SUBSTANCE P;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CAT; CONTROLLED STUDY; CORTICOSTEROID THERAPY; CYTOKINE RELEASE; DRUG EFFECT; DRUG EFFICACY; NERVE DECOMPRESSION; NERVE ROOT COMPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL GANGLION; SPINAL ROOT; ANIMAL; DECOMPRESSION SURGERY; DISEASE MODEL; PATHOLOGY; POSTOPERATIVE PAIN; RADICULOPATHY;

ADRENAL CORTEX HORMONES; ANIMALS; ANTIGENS, CD4; ANTIGENS, CD5; CATS; DECOMPRESSION, SURGICAL; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; PAIN, POSTOPERATIVE; RADICULOPATHY; SPINAL NERVE ROOTS; SUBSTANCE P;

EID: 0036783168     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/00003086-200210000-00036     Document Type: Article

References (20)

1. Abbadie C, Brown JL, Mantyh PW, Basbaum Al: Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain. Neuroscience 70:201-209, 1996.
2. Abbas AK, Murphy KM, Sher A: Functional diversity of helper T lymphocytes. Nature 383:787-793, 1996.
3. Borson DB, Gruenert DC: Glucocorticoids induce neutral endopeptidase in transformed human tracheal epithelial cells. Am J Physiol 260:L83-L89, 1991.
4. Bush K, Cowan N, Katz D, Gishen P: The natural history of sciatica associated with disc pathology: A prospective study with clinical and independent radiologic follow-up. Spine 17:1205-1212, 1992.
5. Cao YQ, Mantyh PW. Carlson EJ, et al: Primary afferent tachykinins are required to experience moderate to intense pain. Nature 392:390-394, 1998.
6. Coppes MH, Marani E, Thomeer RTWM, Groen GJ: Innervation of 'painful' lumbar discs. Spine 22:2342-2350, 1997.
7. Cuckler MJ, Bernini PA, Wiesel SW. et al: The use of epidural steroids in the treatment of lumbar radicular pain: A prospective randomized double-blind study. J Bone Joint Surg 67A:980-983, 1985.
8. Delamarter RB, Bohlman HH, Dodge LD, Biro C: Experimental lumbar spinal stenosis. J Bone Joint Surg 72A:110-120, 1990.
9. Felipe CD, Herrero JF, O'Brien JA, et al: Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature 392:394-397, 1998.
10. Foulkes GD, Robinson JSJ: Intraoperative dexamethasone irrigation in lumbar microdiskectomy. Clin Orthop 261:224-228, 1990.
11. Freemont AJ, Peacock TE, Goupille P, et al: Nerve ingrowth into diseased intervertebral disc in chronic back pain. Lancet 350:178-181, 1997.
12. Glasser RS, Knego RS, Delashaw JB, Fessler RG: The peri-operative use of corticosteroids and bupivacaine in the management of lumbar disc disease. J Neurosurg 78:383-387, 1993.
13. Green LN: Dexamethasone in the management of symptoms due to herniated lumbar disc. J Neurol Neurosurg Psychiatry 38:1211-1217, 1975.
14. Hayashi N, Weinstein JN, Meller ST, et al: The effect of epidural injection of betamethasone or bupivacaine in a rat model of lumbar radiculopathy. Spine 23:877-885, 1998.
15. Kraemer J, Ludwig J, Bickert U, Owczarek V, Traupe M: Lumbar epidural perineural injection: A new technique. Eur Spine J 6:357-361, 1997.
16. Olmarker K, Rydevik B, Holm S: Edema formation in spinal nerve roots induced by experimental, graded compression: An experimental study on the pig cauda equina with special reference to differences in effects between rapid and slow onset of compression. Spine 14:569-573, 1989.
17. Porsman O, Friis H: Prolapsed lumbar disc treated with intramuscularly administered dexamethasonephosphate: A prospectively planned, double-blind controlled clinical trial in 52 patients. Scand J Rheumatol 8:142-144, 1979.
18. Rydevik BL, Myers RR, Powell HC: Pressure increase in the dorsal root ganglion following mechanical compression: Closed compartment syndrome in nerve roots. Spine 14:574-576, 1989.
19. Schaffer M, Beiter T, Becker HD, Hunt TK: Neuropeptides: Mediators of inflammation and tissue repair? Arch Surg 133:1107-1116, 1998.
20. Watters WC, Temple AP, Granberry M: The use of dexamethasone in primary lumbar disc surgery: A prospective, randomized double-blind study. Spine 14:440-442, 1989.