A new method for synthesis of 7-deoxytaxane analogues by hydrogenation of Δ6,7-taxane derivatives

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 10, 2002, Pages 1398-1400

  Takeda, Yasuyuki ^a   Yoshino, Toshiharu ^a   Uoto, Kouichi ^a   Terasawa, Hirofumi ^a   Soga, Tsunehiko ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

7 deoxytaxane analogue; Hydrogenation; New efficient method

Indexed keywords

4 ACETOXY 2 BENZOYLOXY 1,13 DIHYDROXY 5,20 EPOXY 9,10 (ISOPROPYLIDENEDIOXY) TAX 6,11 DIENE; 4 ACETOXY 2 BENZOYLOXY 5,20 EPOXY 10 FORMYLOXY 1,13 DIHYDROXY 9 OXO 7 TRIFLUOROMETHANESULFONYLOXYTAX 11 ENE; 4 ACETOXY 2 BENZOYLOXY 5,20 EPOXY 10 FORMYLOXY 9 OXO 1,7,13 TRIHYDROXYTAX 11 ENE; 4 ACETOXY 2 BENZOYLOXY 5,20 EPOXY 9 OXO 1,10,13 TRIHYDROXYTAX 11 ENE; 4 ACETOXY 2 BENZOYLOXY 5,20 EPOXY 9 OXO 1,10,13 TRIHYDROXYTAX 6,11 DIENE; 4 ACETOXY 2 CYCLOHEXANECARBONYLOXY 5,20 EPOXY 9 OXO 1,10,13 TRIHYDROXYTAX 11 ENE; CARBON; PALLADIUM; TAXANE DERIVATIVE; UNCLASSIFIED DRUG; BRIDGED COMPOUND; TAXANE; TAXOID;

ARTICLE; CATALYST; DRUG SYNTHESIS; HYDROGENATION; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; CHEMISTRY; SYNTHESIS;

BRIDGED COMPOUNDS; HYDROGENATION; TAXOIDS;

EID: 0036782881     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.1398     Document Type: Article

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