Acute ingestion of red wine by men activates platelets but does not influence endothelial markers: No effect of white wine

Blood Coagulation and Fibrinolysis

Volumn 13, Issue 7, 2002, Pages 647-651

  Blann, A D ^a   Williams, N R ^a   Lip, G Y H ^a   Rajput Williams, J ^a   Howard, A N ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

thromboglobulin; Endothelium; Platelets; Polyphenols; Soluble P selectin; Soluble thrombomodulin; Von Willebrand factor; Wine

Indexed keywords

BETA THROMBOGLOBULIN; PADGEM PROTEIN; POLYPHENOL; THROMBOMODULIN; VON WILLEBRAND FACTOR; ALCOHOL; BIOLOGICAL MARKER;

ADULT; ALCOHOL CONSUMPTION; ALCOHOLIC BEVERAGE; ARTICLE; BLOOD SAMPLING; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMATOLOGICAL PARAMETERS; HUMAN; INGESTION; MALE; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; VASCULAR ENDOTHELIUM; WINE; AGED; BLOOD; DRUG EFFECT; MIDDLE AGED;

ADULT; AGED; BETA-THROMBOGLOBULIN; BIOLOGICAL MARKERS; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; ETHANOL; HUMANS; MALE; MIDDLE AGED; PLATELET ACTIVATION; WINE;

EID: 0036775078     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-200210000-00011     Document Type: Article

References (28)

1. Chadwick DJ, Goode JA (Eds). Alcohol and Cardiovascular Diseases. Chichester: Wiley; 1998.
2. Klatsky AL. Alcohol, coronary disease and hypertension. Annu Rev Med 1996; 47: 149-160.
3. Hart CL, Davey Smith G, Hole DJ, Hawthorne VM. Alcohol consumption and mortality from all causes, coronary heart disease, and stroke: Results from a prospective cohort study of Scottish men with 21 years of follow up. BMJ 1999; 318: 1725-1729.
4. Masarei JRL, Puddey IB, Rouse IL, Lynch WJ, Vandongen R, Beilin LJ. Effects of alcohol consumption on serum lipoprotein-lipid and apolipoprotein concentrations. Atherosclerosis 1986; 60: 79-87.
5. Brunner EJ, Marmot MG, White IR, O'Brien JR, Etherington MD, Slavin BM, et al. Gender and employment grade differences in blood cholesterol, apolipoproteins and haemostatic factors in the White-hall II study. Atherosclerosis 1993; 102: 195-207.
6. Iso H, Folsum AR, Koike KA, Sato S, Wu KK, Shimamoto T, et al. Antigens of tissue plasminogen activator and plasminogen activator inhibitor 1: Correlates in non-smoking Japanese and Caucasian men and women. Thromb Haemostas 1993; 70: 475-480.
7. Ridker PM, Vaughan DE, Stampfer MJ, Glynn RJ, Hennekens CH. Association of moderate alcohol consumption and plasma concentration of endogenous tissue-type plasminogen activator. JAMA 1994; 272: 929-933.
8. Dimmitt SB, Rakic V, Puddey IB, Baker R, Oostryck R, Adams MJ, et al. The effects of alcohol on coagulation and fibrinolytic factors: A controlled trial. Blood Coagul Fibrinolysis 1998; 9: 39-45.
9. Gill JS, Shipley MJ, Tsemwentzis SA, Hornby RS, Gill SK, Hitchcock ER, et al. Alcohol consumption - A risk factor for haemorrhagic and non-haemorrhagic stroke. Am J Med 1991; 90: 489-497.
10. Rimm EB, Klatsky A, Grobbee D, Stampfer MJ. Review of moderate alcohol consumption and reduced risk of coronary heart disease: Is the effect due to beer, wine or spirits? Br Med J 1996; 312: 731-736.
11. Ross R. Atherosclerosis: An inflammatory disease. N Engl J Med 1999; 340: 115-126.
12. Blann AD, Lip GYH. Hypothesis: Is soluble P selectin a new marker of platelet activation? Atherosclerosis 1997; 128: 135-138.
13. Blann AD, Taberner DA. A reliable marker of endothelial cell activation: Does it exist? Br J Haematol 1995; 90: 244-248.
14. Feinberg WM, Pearce LA, Hart RG, Cushman M, Cornell ES, Lip GYH, Bovill EG. Markers of thrombin and platelet activity in patients with atrial fibrillation: Correlation with stroke among 1531 participants in the stroke prevention in atrial fibrillation III study. Stroke 1999; 30: 2547-2553.
15. Wagner DD. Cell biology of von Willebrand factor. Ann Rev Cell Biol 1990; 6: 217-246.
16. Pattichis K, Louca LL, Jarman J, Sandler M, Glover V. 5-Hydroxytryptamine release from platelets by different red wines: Implications for migraine. Eur J Pharmacol 1995; 292: 173-177.
17. Lale A, Herbert JM, Augereau JM, Billon M, Leconte M, Gleye J. Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes. J Nat Prod 1996; 59: 273-276.
18. Caccetta RA, Croft KD, Beilin LJ, Puddey IB. Ingestion of red wine significantly increases plasma phenolic acid concentrations but does not acutely affect ex vivo lipoprotein oxidizability. Am J Clin Nutr 2000; 71: 67-74.
19. Emopoulos CA, Pinckard RN, Hanahan DJ. Platelet activating factor. Evidence for 1-0-alkyl-2-acetyl-sn-gylceryl-3-phosphorylcholine as the active component (a new class of lipid chemical mediators). J Biol Chem 1979; 254: 9355-9358.
20. Fragopoulou E, Nomikos T, Tsantila N, Mitropoulou A, Zabetakis I, Demopoulos CA. Biological activity of total lipids from red and white wine/Must. J Agric Food Chem 2001; 49: 5186-5193.
21. Day A, Stansbie D. Cardioprotective effect of red wine may be mediated by urate. Clin Chem 1995; 41: 1319-1320.
22. Numminen H, Kobayashi M, Uchiyama S, Iwata M, Ikeda Y, Riutta A, et al. Effects of alcohol and the evening meal on shear induced platelet aggregation and urinary excretion of prostanoids. Alcohol 2000; 35: 594-600.
23. Rein D, Paglieroni TG, Pearson DA, Wun T, Schmitz HH, Gosselin R, Keen CL. Cocoa and wine polyphenols modulate platelet activation and function. J Nutr 2000; 130: 2120S-2126S.
24. Renaud SC, Ruf JC. Effects of alcohol on platelet function. Clin Chim Acta 1996; 246: 77-89.
25. Lacoste L, Hung J, Lam JYT. Acute and delayed antithrombotic effects of alcohol in humans. Am J Cardiol 2001; 87: 82-85.
26. Conlan MG, Folsom AR, Finch A, Davis CE, Sorlie P, Marcucci G, Ku KK. Associations of factor VII and von Willebrand factor with age, race, sex and risk factors for atherosclerosis. Thromb Haemostas 1993; 70: 380-385.
27. Kumari M, Marmot M, Brunner E. Social determinants of von Willebrand factor. Arterioscl Thromb Vasc Biol 2000; 20: 1842-1847.
28. Mukamal KJ, Jadhav PP, D'Agostino RB, Massaro JM, Mittleman MA, Lipinska I, et al. Alcohol consumption and hemostatic factors. Analysis of the Framingham Offspring Cohort. Circulation 2001; 16: 1367-1373.