Pachyclavulariaenones D-G, new diterpenoids from the soft coral Pachyclavularia violacea

Journal of Natural Products

Volumn 65, Issue 10, 2002, Pages 1475-1478

  Wang, Guey Horng ^a   Sheu, Jyh Horng ^a   Duh, Chang Yih ^a   Chiang, Michael Y ^a  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DITERPENOID; PACHYCLAVULARIAENONE D; PACHYCLAVULARIAENONE E; PACHYCLAVULARIAENONE F; PACHYCLAVULARIAENONE G; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CORAL; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PACHYCLAVULARIA VIOLACEA; STEREOCHEMISTRY; X RAY ANALYSIS;

ANIMALS; ANTHOZOA; ANTINEOPLASTIC AGENTS; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; SPECTRUM ANALYSIS; TUMOR CELLS, CULTURED;

ALCYONACEA; ANTHOZOA; PACHYCLAVULARIA;

EID: 0036773510     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np020095d     Document Type: Article

References (19)

1. Sheu, J.-H.; Hung, K.-C.; Wang, G.-H.; Duh, C.-Y. J. Nat. Prod. 2000, 63, 1603-1607.
2. Sheu, J.-H.; Sung, P.-J.; Huang, L.-H.; Lee, S.-F.; Wu, T.; Chang, B.-Y.; Duh, C.-Y.; Fang, L.-S.; Soong, K.; Lee, T.-J. J. Nat. Prod. 1996, 59, 935-938.
3. Sheu, J.-H.; Sung, P.-J.; Cheng, M.-C.; Liu, H.-Y.; Fang, L.-S.; Duh, C.-Y.; Chiang, M. Y. J. Nat. Prod. 1998, 61, 602-608.
4. Sung, P.-J.; Su, J.-H.; Wang, G.-H.; Lin, S.-F.; Duh, C.-Y.; Sheu, J.-H. J. Nat. Prod. 1999, 62, 457-463.
5. Sheu, J.-H.; Sung, P.-J.; Su, J.-H.; Wang, G.-H.; Duh, C.-Y.; Shen, Y.-C.; Chiang, M. Y.; Chen, I.-T. J. Nat. Prod. 1999, 62, 1415-1420.
6. Sheu, J.-H.; Sung, P.-J.; Su, J.-H.; Duh, C.-Y.; Chiang, M. Y. Tetrahedron 1999, 55, 14555-14564.
7. Sung, P.-J.; Su, J.-H.; Duh, C.-Y.; Chiang, M. Y.; Sheu, J.-H. J. Nat. Prod. 2001, 64, 318-323.
8. Wu, S.-L.; Sung, P.-J.; Chiang, M. Y.; Wu, J.-Y.; Sheu, J.-H. J. Nat. Prod. 2001, 64, 1415-1420.
9. Sung, P.-J.; Wu, S.-L.; Fang, H.-J.; Chiang, M. Y.; Wu, J.-Y.; Fang, L.-S.; Sheu, J.-H. J. Nat. Prod. 2000, 63, 1483-1487.
10. Bowden, B. F.; Coll, J. C.; Vasilescu, I. M.; Alderslade, P. M. Aust. J. Chem. 1989, 42, 1727-1734.
11. Bayer, F. M. Proc. Biol. Soc. Wash. 1981, 94, 902-947.
12. Bowden, B. F.; Coll, J. C.; Mitchell, S. J.; Raston, C. L.; Stokie, G. J.; White, A. H. Aust. J. Chem. 1979, 32, 2265-2274.
13. Imman, W.; Crews, P. J. Org. Chem. 1989, 54, 2526-2529.
14. Xu, L.; Patrick, B. O.; Roberge, M.; Allen, T.; van Ofwegen, L.; Andersen, R. J. Tetrahedron 2000, 56, 9031-9037.
15. Wang, G.-H.; Sheu, J.-H.; Chiang, M. Y.; Lee, T.-J. Tetrahedron Lett. 2001, 42, 2333-2336.
16. Sheu, J.-H.; Wang, G.-H.; Sung, P.-J.; Duh, C.-Y.; Chiang, M. Y. Tetrahedron 2001, 57, 7639-7648.
17. 50 value of ≤ 4.0 μg/mL is required. Geran, R. I.; Greenberg, N. H.; MacDonald, M. M.; Schumacher, A. M.; Abbott, B. J. Cancer Chemother. Rep. 1972, (3), 1-91.
18. Atomic coordinates for structure 3 have been deposited with the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK.
19. Sheu, J.-H.; Liaw, C.-C.; Duh, C.-Y. J. Nat. Prod. 1995, 58, 1521-1526.