Effect of cadmium on bromosulfophthalein kinetics in the isolated perfused rat liver system

Toxicological Sciences

Volumn 69, Issue 2, 2002, Pages 460-469

  Soto, Armando ^a   Foy, Brent D ^b   Frazier, John M ^c  

^a ALION SCIENCE AND TECHNOLOGY   (United States)

^b WRIGHT STATE UNIVERSITY   (United States)

^c AIR FORCE RESEARCH LABORATORY   (United States)

Author keywords

Biokinetics; Bromosulfophthalein; Cadmium; Cholestasis; Isolated perfused rat liver

Indexed keywords

ALBUMIN; BROMSULFOPHTHALEIN; CADMIUM; GLUTATHIONE; LACTATE DEHYDROGENASE;

ANIMAL TISSUE; ARTICLE; BILE FLOW; CHOLESTASIS; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; HEPATOBILIARY SYSTEM; ISOLATED LIVER; LIVER CELL; LIVER FUNCTION TEST; LIVER NECROSIS; LIVER PERFUSION; LIVER SINUSOID; LIVER TOXICITY; MALE; NONHUMAN; RAT;

ANIMALS; BILE; BODY WEIGHT; CADMIUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLORING AGENTS; L-LACTATE DEHYDROGENASE; LIVER; MALE; ORGAN SIZE; PERFUSION; RATS; RATS, INBRED F344; SULFOBROMOPHTHALEIN;

ANIMALIA; BOVINAE; MARTES PENNANTI;

EID: 0036773414     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/69.2.460     Document Type: Article

References (26)

1. Bagchi, D., Bagchi, M., Hassoun, E. A., and Stohs, S. J. (1996). Cadmium-induced excretion of urinary lipid metabolites, DNA damage, glutathione depletion, and hepatic lipid peroxidation in Sprague-Dawley rats. Biol. Trace Elem. Res. 52, 143-154.
2. Ballatori, N., and Truong, A. T. (1989). Relation between biliary glutathione excretion and bile acid-independent bile flow. Am. J. Physiol. 256, G22-G30.
3. Chin, T. A., and Templenton, D. M. (1993). Protective elevations of glutathione and metallothionein in cadmium-exposed mesangial cells. Toxicology 77, 145-156.
4. Chuttani, H. K., Gupta, P. S., Gulati, S., and Gupta, D. H. (1965). Acute copper sulfate poisoning. Am. J. Med. 39, 849-854.
5. Colon, A. R., Pardo, V., and Sandberg, D. H. (1974). Experimental Reye's Syndrome induced by viral potentiation of chemical toxin. In Reye's Syndrome (J. D. Pollack, Ed.), pp. 194-214. Grune and Stratton, New York.
6. Gores, G. J., Kost, L. J., and LaRusso, N. F. (1986). The isolated perfused rat liver: Conceptual and practical considerations. Hepatology 6, 511-517.
7. Goyer, R. A., and Cherian, M. G. (1995). Renal effects of metals. In Metal Toxicology (R. A. Goyer, C. D. Klaassen, and M. P. Waalkes, Eds.), pp. 389-412. Academic Press, San Diego, CA.
8. Hyman, J. (1999). Hepatotoxicity: The Adverse Effects of Drugs and Others Chemicals on the Liver, 2nd ed., pp. 295-323. Lippincott Williams & Wilkins, Philadelphia, PA.
9. Kang, Y. J. (1992). Exogenous glutathione decreases cellular cadmium uptake and toxicity. Drug Metab. Dispos. 20, 714-718.
10. Korzeniewski, C., and Callewaert, D. M. (1983). An enzyme-release assay for natural cytotoxicity. J. Immunol. Methods 64, 313-320.
11. Kullak-Ublick, G. A. (1999). Regulation of organic anion and drug transporters of the sinusoidal membrane. J. Hepatol. 31, 563-573.
12. Li, W., Zhao, Y., and Chou, I. N. (1993). Alterations in cytoskeletal protein sulfhydryls and cellular glutathione in cultured cells exposed to cadmium and nickel ions. Toxicology 77, 65-79.
13. Miura, H., Tazuma, S., Yamashita, G., Hatsushika, S., and Kajiyama, G. (1997). Effect of cholestasis induced by organic anion on the lipid composition of hepatic membrane subfractions and bile in rats. J. Gastroenterol. Hepatol. 12, 734-739.
14. Muller, L., and Ohnesorge, F. K. (1982). Different response of liver parenchymal cells from starved and fed rats to cadmium. Toxicology 25, 141-150.
15. Perrin, D. D., and Watt, A. E. (1971). Complex formation of zinc and cadmium with glutathione. Biochim. Biophys. Acta 230, 96-104.
16. Stacey, N. H., Cantilena, L. R., Jr., and Klaassen, C. D. (1980). Cadmium toxicity and lipid peroxidation in isolated rat hepatocytes. Toxicol. Appl. Pharmacol. 53, 470-480.
17. Strubelt, O., Kremer, J., Tilse, A., Keogh, R., Pentz, R., and Younes, M. (1996). Comparative studies of the toxicity of mercury, cadmium and copper toward the isolated perfused rat liver. J. Toxicol. Environ. Health 47, 267-283.
18. Sugawara, N., Lai, Y.-R., Arizono, K., and Ariyoshi, T. (1996). Biliary excretion of exogenous cadmium and endogenous copper and zinc in the Eisai hyperbilirubinuric (EHB) rat with a near absence of biliary glutathione. Toxicology 112, 87-94.
19. Sugawara, N., Lai, Y.-R., Arizono, K., Kitajima, T., and Inoue, H. (1997). Lack of biliary excretion of Cd linked to an inherent defect of the canalicular isoform of multidrug resistance protein (cMrp) does not abnormally stimulate accumulation of Cd in the Eisai hyperbilirubinemic (EHB) rat liver. Arch. Toxicol. 71, 336-339.
20. Toxopeus, C., and Frazier, J. M. (1999). The isolated perfused rat liver and its use in the study of chemical kinetics: Quality and performance parameters. Air Force Technical Report No. AFRL-HE-WP-TR-1998-0134.
21. Tuchweber, B., Weber, A., Roy, C. C., and Yousef, I. M. (1986). Mechanisms of experimentally induced intrahepatic cholestasis. Prog. Liver Dis. 8, 161-178.
22. Vos, T. A., Ros, J. E., Havinga, R., Moshage, H., Kuipers, F., Jansen, P. L., and Muller, M. (1999). Regulation of hepatic transport systems involved in bile secretion during liver regeneration in rats. Hepatology 29, 1833-1839.
23. Webb, M., and Cain, K. (1982). Functions of metallothionein. Biochem. Pharmacol. 31, 137-142.
24. Whelan, G., Hoch, J., and Combes, B. (1970). A direct assessment of the importance of conjugation for biliary transport of sulfobromophthalein sodium. J. Lab. Clin. Med. 75, 542-557.
25. Will, Y. (1999) The glutathione pathway. In Current Protocols in Toxicology (M. D. Maines, L. G. Costa, D. J. Reed, S. Sassa, and I. G. Sipes, Eds.), pp. 6.1.1-6.1.18. John Wiley and Sons, Corvallis, OR.
26. Winkler, K. (1965). The kinetics of bromosulfophthalein elimination during continuous infusion in man. In The Biliary System (W. Taylor, Ed.), pp. 551-566. FA Davis, Philadelphia.