Human ocular mast cells

Current Opinion in Allergy and Clinical Immunology

Volumn 2, Issue 5, 2002, Pages 419-422

  Church, Martin K ^a   McGill, James I ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Histamine; Mast cell; Seasonal allergic conjunctivitis

Indexed keywords

CHROMONE DERIVATIVE; CROMOGLYCATE DISODIUM; CYTOKINE; EYE DROPS; HISTAMINE; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR; HISTAMINE H4 RECEPTOR; INTERLEUKIN 4; MESSENGER RNA; NEDOCROMIL SODIUM; PROSTAGLANDIN D2; RANITIDINE; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC CONJUNCTIVITIS; CELL ACTIVATION; CELL ACTIVITY; CELL COUNT; CELL FUNCTION; CLINICAL FEATURE; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; EOSINOPHILIA; HISTAMINE RELEASE; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNE RESPONSE; INFLAMMATION; MAST CELL; MEDIATOR RELEASE; PATHOPHYSIOLOGY; PEPTIC ULCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SEASONAL VARIATION;

EID: 0036772695     PISSN: 15284050     EISSN: None     Source Type: Journal    
DOI: 10.1097/00130832-200210000-00009     Document Type: Review

References (33)

1. Bacon AS, Ahluwalia P, Irani AM, et al. Tear and conjunctival changes during the allergen-induced early and late phase responses. J Allergy Clin Immunol 2000; 106:948-954.
2. McGill JI, Holgate ST, Church MK, et al. Allergic eye disease mechanisms. Br J Ophthalmol 1998; 82:1203-1214.
3. Church MK, Levi Schaffer F. The human mast cell. J Allergy Clin Immunol 1997; 99:155-160.
4. Furitsu T, Saito H, Dvorak AM, et al. Development of human mast cells in vitro. Proc Natl Acad Sci U S A 1989; 86: 10039-10043.
5. TC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies. J Histochem Cytochem 1989; 37: 1509-1515.
6. Irani AA, Schechter NM, Craig SS, et al. Two types of human mast cells that have distinct neutral protease compositions. Proc Natl Acad Sci U S A 1986; 83:4464-4468.
7. Baddeley SM, Bacon AS, McGill JI, et al. Mast cell distribution and neutral protease expression in acute and chronic allergic conjunctivitis. Clin Exp Allergy 1995; 25:41-50.
8. Irani AA. Ocular mast cells and mediators [abstract]. Immunol Allergy Clin North Am 1997; 17:1.
9. Walls AF, Bennett AR, McBride HM, et al. Production and characterization of monoclonal antibodies specific for human mast cell tryptase. Clin Exp Allergy 1990; 20:581-589.
10. Lowman MA, Rees PH, Benyon RC, Church MK. Human mast cell heterogeneity: Histamine release from mast cells dispersed from skin, lung, adenoids, tonsils and intestinal mucosa in response to IgE-dependent and non-immunological stimuli. J Allergy Clin Immunol 1988; 81:590-597.
11. Valent P, Schernthaner GH, Sperr WR, et al. Variable expression of activation linked surface antigens on human mast cells in health and disease. Immunol Rev 2001; 179:74-81. An excellent recent review detailing the heterogeneity of membrane receptors on human mast cells.
12. Lowman MA, Benyon RC, Church MK. Characterization of neuropeptide-induced histamine released from human dispersed skin mast cells. Br J Pharmacol 1988; 95:121-130.
13. Campbell AM, Demoly P, Michel FB, Bousquet J. Conjunctival provocation tests with codeine phosphate: Effect of disodium cromoglycate. Ann Allergy 1993; 71:51-55.
14. Church MK, Hiroi J. Inhibition of IgE-dependent histamine release from human dispersed lung mast cells by anti-allergic drugs and salbutamol. Br J Pharmacol 1987; 90:421-429.
15. 1-antihistamine on symptoms, mast cell mediator release during the early-phase response, and both adhesion protein expression and infiltration of inflammatory cells during the late-phase response. The data in this paper suggest that nedocromil sodium, in addition to its effects on mast cell mediator release, may have additional effects on itching. The possible mechanisms of this were explored in a subsequent study in the skin (Ahluwalia P, McGill JI, Church MK. Nedocromil sodium inhibits histamine-induced itch and flare in human skin. Br J Pharmacol 2001; 132:613-615).
16. 1-antihistamine on symptoms, mast cell mediator release during the early-phase response, and both adhesion protein expression and infiltration of inflammatory cells during the late-phase response. The data in this paper suggest that nedocromil sodium, in addition to its effects on mast cell mediator release, may have additional effects on itching. The possible mechanisms of this were explored in a subsequent study in the skin (Ahluwalia P, McGill JI, Church MK. Nedocromil sodium inhibits histamine-induced itch and flare in human skin. Br J Pharmacol 2001; 132:613-615).
17. Ehrlich P. Beitrage zur Theorie und Praxis der Histologischen Farbung [doctoral thesis]. Leipzig: University of Leipzig; 1878.
18. McGill JI, Zhang S, Anderson DF, et al. Human mast cells synthesise and store c-kit ligand (stem cell factor) [abstract]. Vision Res 1996; 36:308.
19. 2-like cytokines. Invest Ophthalmol Vis Sci 2001; 42:995-1001. An immunohistochemical paper examining the distribution of cytokines in conjunctival mast cells.
20. Ahluwalia P. The Action of Anti-Allergic Drugs in Seasonal Allergic Conjunctivitis [PhD thesis]. Southampton: University of Southampton; 2000.
21. Bradding P, Feather IH, Wilson S, et al. Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects: The mast cell as a source of IL-4, IL-5 and IL-6 in human allergic mucosal inflammation. J Immunol 1993; 151:3853-3865.
22. MacLeod JD, Anderson DF, Baddeley SM, et al. Immunolocalization of cytokines to mast cells in normal and allergic conjunctiva. Clin Exp Allergy 1997; 27:1328-1334.
23. Barnes PJ. Nuclear factor kappa B. Int J Biochem Cell Biol 1997; 29:867-870.
24. Coward WR, Okayama Y, Sagara H, et al. NF-κB and TNF-α: A positive autocrine loop in human lung mast cells? J Immunol 2002 (in press).
25. 2 in human skin. Clin Allergy 1988; 18:619-627.
26. 4) in human skin. J Invest Dermatol 1983; 80:115-119.
27. Gether U. Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr Rev 2000; 21:90-113.
28. 2-] oscillation frequency regulates agonist-stimulated NF-κB transcriptional activity. J Biol Chem 1999; 274:33995-33998.
29. q/11-subunits in constitutive and agonist-mediated signaling. Mol Pharmacol 2001; 60:1133-1142.
30. 1 antihistamines. The finding that they are inverse agonists rather than receptor antagonists, as believed previously, has tremendous implications for the use of these drugs and for the development of new antihistamines.
31. Schwartz JC, Arrang JM, Garbarg M, et al. Histaminergic transmission in the mammalian brain. Physiol Rev 1991; 71:1-51.
32. Zhu Y, Michalovich D, Wu H, et al. Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol Pharmacol 2001; 59:434-441.
33. Nguyen T, Shapiro DA, George SR, et al. Discovery of a novel member of the histamine receptor family. Mol Pharmacol 2001;59:427-433.