메뉴 건너뛰기




Volumn 9, Issue 5, 2002, Pages 534-541

Heterogeneity of myocardial blood flow and metabolism: Review of physiologic principles and implications for radionuclide imaging of the heart

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMMONIA; CARBON 11; FLUORODEOXYGLUCOSE F 18; NITROGEN 13; OXYGEN; OXYGEN 15; PALMITIC ACID DERIVATIVE; RADIOISOTOPE; TRACER; WATER;

EID: 0036765547     PISSN: 10713581     EISSN: None     Source Type: Journal    
DOI: 10.1067/mnc.2002.125916     Document Type: Review
Times cited : (7)

References (49)
  • 1
    • 0032411316 scopus 로고    scopus 로고
    • Spatial heterogeneity of myocardial perfusion and metabolism
    • Decking UK, Schrader J. Spatial heterogeneity of myocardial perfusion and metabolism. Basic Res Cardiol 1998;93:439-45.
    • (1998) Basic Res. Cardiol. , vol.93 , pp. 439-445
    • Decking, U.K.1    Schrader, J.2
  • 2
    • 0033462230 scopus 로고    scopus 로고
    • Functional heterogeneity of oxygen supply-consumption ratio in the heart
    • Zuurbier CJ, van Iterson M, Ince C. Functional heterogeneity of oxygen supply-consumption ratio in the heart. Cardiovasc Res 1999;44:488-97.
    • (1999) Cardiovasc. Res. , vol.44 , pp. 488-497
    • Zuurbier, C.J.1    van Iterson, M.2    Ince, C.3
  • 3
    • 0024440958 scopus 로고
    • Fractal nature of regional myocardial blood flow heterogeneity
    • Bassingthwaighte JB, King RB, Roger SA. Fractal nature of regional myocardial blood flow heterogeneity. Circ Res 1989;65: 578-90.
    • (1989) Circ. Res. , vol.65 , pp. 578-590
    • Bassingthwaighte, J.B.1    King, R.B.2    Roger, S.A.3
  • 4
    • 0030056792 scopus 로고    scopus 로고
    • Spatial heterogeneity of blood flow in the dog heart. II. Temporal stability in response to adrenergic stimulation
    • Deussen A, Flesche CW, Lauer T, Sonntag M, Schrader J. Spatial heterogeneity of blood flow in the dog heart. II. Temporal stability in response to adrenergic stimulation. Pflugers Arch 1996;432:451-61.
    • (1996) Pflugers Arch. , vol.432 , pp. 451-461
    • Deussen, A.1    Flesche, C.W.2    Lauer, T.3    Sonntag, M.4    Schrader, J.5
  • 5
    • 0030057168 scopus 로고    scopus 로고
    • Spatial heterogeneity of blood flow in the dog heart. I. Glucose uptake, free adenosine and oxidative/glycolytic enzyme activity
    • Sonntag M, Deussen A, Schultz J, Loncar R, Hort W, Schrader J. Spatial heterogeneity of blood flow in the dog heart. I. Glucose uptake, free adenosine and oxidative/glycolytic enzyme activity. Pflugers Arch 1996;432:439-50.
    • (1996) Pflugers Arch. , vol.432 , pp. 439-450
    • Sonntag, M.1    Deussen, A.2    Schultz, J.3    Loncar, R.4    Hort, W.5    Schrader, J.6
  • 8
    • 0021858930 scopus 로고
    • Stability of heterogeneity of myocardial blood flow in normal awake baboons
    • King RB, Bassingthwaighte JB, Hales JRS, Rowell LB. Stability of heterogeneity of myocardial blood flow in normal awake baboons. Circ Res 1985;57:285-95.
    • (1985) Circ. Res. , vol.57 , pp. 285-295
    • King, R.B.1    Bassingthwaighte, J.B.2    Hales, J.R.S.3    Rowell, L.B.4
  • 11
    • 0031060467 scopus 로고    scopus 로고
    • Quantitative PET measurements of regional myocardial blood flow: Observations in humans with ischemic heart disease
    • Gewirtz H, Skopicki HA, Abraham SA, Castano H, Dinsmore RE, Alpert NM, et al. Quantitative PET measurements of regional myocardial blood flow: observations in humans with ischemic heart disease. Cardiology 1997;88:62-70.
    • (1997) Cardiology , vol.88 , pp. 62-70
    • Gewirtz, H.1    Skopicki, H.A.2    Abraham, S.A.3    Castano, H.4    Dinsmore, R.E.5    Alpert, N.M.6
  • 12
    • 0014602157 scopus 로고
    • Total and regional coronary blood flow measured by radioactive microspheres in conscious and anesthetized dogs
    • Domenech RJ, Hoffman JIE, Nobel MIM. Total and regional coronary blood flow measured by radioactive microspheres in conscious and anesthetized dogs. Circ Res 1969;25:581-96.
    • (1969) Circ. Res. , vol.25 , pp. 581-596
    • Domenech, R.J.1    Hoffman, J.I.E.2    Nobel, M.I.M.3
  • 14
    • 0016188759 scopus 로고
    • Total and regional myocardial blood flow measurements with 25 micron, 15 micron, 9 micron, and filtered 1-10 micron diameter microspheres and antipyrine in dogs and sheep
    • Utley J, Carlson EL, Hoffman JI, Martinez HM, Buckberg GD. Total and regional myocardial blood flow measurements with 25 micron, 15 micron, 9 micron, and filtered 1-10 micron diameter microspheres and antipyrine in dogs and sheep. Circ Res 1974; 34:391-405.
    • (1974) Circ. Res. , vol.34 , pp. 391-405
    • Utley, J.1    Carlson, E.L.2    Hoffman, J.I.3    Martinez, H.M.4    Buckberg, G.D.5
  • 15
  • 16
    • 0029782666 scopus 로고    scopus 로고
    • Myocardial adaptation during and after sustained, demand-induced ischemia observations in closed-chest, domestic swine
    • Berman M, Fischman AJ, Southern J, Carter E, Mirecki F, Strauss HW, et al. Myocardial adaptation during and after sustained, demand-induced ischemia observations in closed-chest, domestic swine. Circulation 1996;94:755-62.
    • (1996) Circulation , vol.94 , pp. 755-762
    • Berman, M.1    Fischman, A.J.2    Southern, J.3    Carter, E.4    Mirecki, F.5    Strauss, H.W.6
  • 17
    • 0028838329 scopus 로고
    • Transmural distribution of capillary morphology as a function of coronary perfusion pressure in the resting canine heart
    • May-Newman K, Mathieu-Costello O, Omens JH, Klumb K, McCulloch AD. Transmural distribution of capillary morphology as a function of coronary perfusion pressure in the resting canine heart. Microvasc Res 1995;50:381-96.
    • (1995) Microvasc. Res. , vol.50 , pp. 381-396
    • May-Newman, K.1    Mathieu-Costello, O.2    Omens, J.H.3    Klumb, K.4    McCulloch, A.D.5
  • 18
    • 0012447499 scopus 로고    scopus 로고
    • Coronary blood flow and myocardial ischemia
    • Braunwald EB, editor. 6th ed. Philadelphia: Saunders
    • Ganz P. Coronary blood flow and myocardial ischemia. In: Braunwald EB, editor. Heart disease: a textbook of cardiovascular medicine, 6th ed. Philadelphia: Saunders; 2001.
    • (2001) Heart Disease: A Textbook of Cardiovascular Medicine
    • Ganz, P.1
  • 19
    • 0021275522 scopus 로고
    • Contrasting effects of nifedipine and adenosine on regional flow distribution and metabolism distal to a severe coronary arterial stenosis: Observations in sedated, closed-chest domestic swine
    • Gewirtz H, Gross SL, Williams DO, Most AS. Contrasting effects of nifedipine and adenosine on regional flow distribution and metabolism distal to a severe coronary arterial stenosis: observations in sedated, closed-chest domestic swine. Circulation 1984;69:1048-57.
    • (1984) Circulation , vol.69 , pp. 1048-1057
    • Gewirtz, H.1    Gross, S.L.2    Williams, D.O.3    Most, A.S.4
  • 20
    • 0033580592 scopus 로고    scopus 로고
    • Relation between coronary "steal" and contractile function at rest in collateral-dependent myocardium of humans with ischemic heart disease
    • Holmvang G, Fry S, Skopicki HA, Abraham SA, Alpert NM, Fischman AJ, et al. Relation between coronary "steal" and contractile function at rest in collateral-dependent myocardium of humans with ischemic heart disease. Circulation 1999;99: 2510-6.
    • (1999) Circulation , vol.99 , pp. 2510-2516
    • Holmvang, G.1    Fry, S.2    Skopicki, H.A.3    Abraham, S.A.4    Alpert, N.M.5    Fischman, A.J.6
  • 21
    • 0030830850 scopus 로고    scopus 로고
    • Effects of dobutamine at maximally tolerated dose on myocardial blood flow in humans with ischemic heart disease
    • [published erratum appears in Circulation 1998;97 414]
    • Skopicki HA, Abraham SA, Picard MH, Alpert NM, Fischman AJ, Gewirtz H. Effects of dobutamine at maximally tolerated dose on myocardial blood flow in humans with ischemic heart disease [published erratum appears in Circulation 1998;97 414]. Circulation 1997;96:3346-52.
    • (1997) Circulation , vol.96 , pp. 3346-3352
    • Skopicki, H.A.1    Abraham, S.A.2    Picard, M.H.3    Alpert, N.M.4    Fischman, A.J.5    Gewirtz, H.6
  • 22
  • 26
    • 0025240006 scopus 로고
    • Coronary microvascular responses to reductions in perfusion pressureEvidence for persistent arteriolar vasomotor tone during coronary hypoperfusion
    • Chilian WM, Layne SM. Coronary microvascular responses to reductions in perfusion pressureEvidence for persistent arteriolar vasomotor tone during coronary hypoperfusion. Circ Res 1990; 66:1227-38.
    • (1990) Circ. Res. , vol.66 , pp. 1227-1238
    • Chilian, W.M.1    Layne, S.M.2
  • 27
    • 0023931404 scopus 로고
    • Transmural differences in sympathetic coronary constriction during exercise in the presence of coronary stenosis
    • Chilian WH, Ackell PH. Transmural differences in sympathetic coronary constriction during exercise in the presence of coronary stenosis. Circ Res 1988;62:216-25.
    • (1988) Circ. Res. , vol.62 , pp. 216-225
    • Chilian, W.H.1    Ackell, P.H.2
  • 29
    • 0029115228 scopus 로고
    • Longitudinal gradients for endothelium-dependent and -independent vascular responses in the coronary microcirculation
    • Kuo L, Davis MJ, Chilian WM. Longitudinal gradients for endothelium-dependent and -independent vascular responses in the coronary microcirculation. Circulation 1995;92:518-25.
    • (1995) Circulation , vol.92 , pp. 518-525
    • Kuo, L.1    Davis, M.J.2    Chilian, W.M.3
  • 31
    • 0029004607 scopus 로고
    • Regulation of coronary blood flow: Coordination of heterogeneous control mechanisms in vascular microdomains
    • Jones CJ, Kuo L, Davis MJ, Chilian WM. Regulation of coronary blood flow: coordination of heterogeneous control mechanisms in vascular microdomains. Cardiovasc Res 1995;29: 585-96.
    • (1995) Cardiovasc. Res. , vol.29 , pp. 585-596
    • Jones, C.J.1    Kuo, L.2    Davis, M.J.3    Chilian, W.M.4
  • 32
    • 0032578478 scopus 로고    scopus 로고
    • Effects of short-term treatment of hyperlipidemia on coronary vasodilator function and myocardial perfusion in regions having substantial impairment of baseline dilator reverse
    • [see comments]
    • Huggins GS, Pasternak RC, Alpert NM, Fischman AJ, Gewirtz H. Effects of short-term treatment of hyperlipidemia on coronary vasodilator function and myocardial perfusion in regions having substantial impairment of baseline dilator reverse [see comments]. Circulation 1998;98:1291-6.
    • (1998) Circulation , vol.98 , pp. 1291-1296
    • Huggins, G.S.1    Pasternak, R.C.2    Alpert, N.M.3    Fischman, A.J.4    Gewirtz, H.5
  • 33
    • 0015813070 scopus 로고
    • Regional distribution of diffusible tracers and carbonized microspheres in the left ventricle of isolated dog hearts
    • Yipintsoi T, Dobbs WA Jr, Scanlon PD, Knopp TJ, Bassingthwaighte JB. Regional distribution of diffusible tracers and carbonized microspheres in the left ventricle of isolated dog hearts. Circ Res 1973;33:573-87.
    • (1973) Circ. Res. , vol.33 , pp. 573-587
    • Yipintsoi, T.1    Dobbs W.A., Jr.2    Scanlon, P.D.3    Knopp, T.J.4    Bassingthwaighte, J.B.5
  • 34
    • 0033577968 scopus 로고    scopus 로고
    • Heterogeneities in myocardial flow and metabolism: Exacerbation with abnormal excitation
    • Bassingthwaighte JB, Li Z. Heterogeneities in myocardial flow and metabolism: exacerbation with abnormal excitation. Am J Cardiol 1999;83:7H-12H.
    • (1999) Am. J. Cardiol. , vol.83
    • Bassingthwaighte, J.B.1    Li, Z.2
  • 35
    • 0016864246 scopus 로고
    • The oxygen pressure histogram in the left ventricular myocardium of the dog
    • Losse B, Schuchhardt S, Niederle N. The oxygen pressure histogram in the left ventricular myocardium of the dog. Pflugers Arch 1975;356:121-32.
    • (1975) Pflugers Arch. , vol.356 , pp. 121-132
    • Losse, B.1    Schuchhardt, S.2    Niederle, N.3
  • 36
    • 16744365333 scopus 로고
    • Blood flow and high-energy phosphates in microregions of left ventricular subendocardium
    • Kleinert HD, Weiss HR. Blood flow and high-energy phosphates in microregions of left ventricular subendocardium. Am J Physiol 1981;240:H804-10.
    • (1981) Am. J. Physiol. , vol.240
    • Kleinert, H.D.1    Weiss, H.R.2
  • 37
    • 0031424986 scopus 로고    scopus 로고
    • Low- and high-blood flow regions in the normal pig heart are equally vulnerable to ischaemia during partial coronary stenosis
    • Bussemaker J, Groeneveld AB, Teerlink T, Hennekes M, Westerhof N, van Beek JH. Low- and high-blood flow regions in the normal pig heart are equally vulnerable to ischaemia during partial coronary stenosis. Pflugers Arch 1997;434:785-94.
    • (1997) Pflugers Arch. , vol.434 , pp. 785-794
    • Bussemaker, J.1    Groeneveld, A.B.2    Teerlink, T.3    Hennekes, M.4    Westerhof, N.5    van Beek, J.H.6
  • 39
  • 40
    • 0026642272 scopus 로고
    • Hibernation and myocardial ischemia: Clinical detection by positron emission tomography
    • Uren NG, Camici PG. Hibernation and myocardial ischemia: clinical detection by positron emission tomography. Cardiovasc Drugs Ther 1992;6:273-9.
    • (1992) Cardiovasc. Drugs Ther. , vol.6 , pp. 273-279
    • Uren, N.G.1    Camici, P.G.2
  • 41
    • 0028836638 scopus 로고
    • Heterogeneity of myocardial perfusion provides the physiological basis of perfusable tissue index
    • Herrero P, Staudenherz A, Walsh J, Gropler R, Bergmann S. Heterogeneity of myocardial perfusion provides the physiological basis of perfusable tissue index. J Nucl Med 1995; 36:320-7.
    • (1995) J. Nucl. Med. , vol.36 , pp. 320-327
    • Herrero, P.1    Staudenherz, A.2    Walsh, J.3    Gropler, R.4    Bergmann, S.5
  • 42
    • 0023272301 scopus 로고
    • The influence of tissue heterogeneity on results of fitting nonlinear model equations to regional tracer uptake curves: With an application to compartmental models used in positron emission tomography
    • Herholz K, Patlak CS. The influence of tissue heterogeneity on results of fitting nonlinear model equations to regional tracer uptake curves: with an application to compartmental models used in positron emission tomography. J Cereb Blood Flow Metab 1987;7:214-29.
    • (1987) J. Cereb. Blood Flow Metab. , vol.7 , pp. 214-229
    • Herholz, K.1    Patlak, C.S.2
  • 43
    • 0022389649 scopus 로고
    • Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data generalizations
    • Patlak CS, Blasberg RG. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data generalizations. J Cereb Blood Flow Metab 1985;5:584-90.
    • (1985) J. Cereb. Blood Flow Metab. , vol.5 , pp. 584-590
    • Patlak, C.S.1    Blasberg, R.G.2
  • 44
    • 0025090511 scopus 로고
    • Redistribution of myocardial fiber strain and blood flow by asynchronous activation
    • Prinzen FW, Augustijn CH, Arts T, Allessie MA, Reneman RS. Redistribution of myocardial fiber strain and blood flow by asynchronous activation. Am J Physiol 1990;259(2 Pt 2): H300-8.
    • (1990) Am. J. Physiol. , vol.259 , Issue.2 PART 2
    • Prinzen, F.W.1    Augustijn, C.H.2    Arts, T.3    Allessie, M.A.4    Reneman, R.S.5
  • 45
    • 0030901476 scopus 로고    scopus 로고
    • A novel method for nonfluoroscopic catheter-based electroanatomical mapping of the heartIn vitro and in vivo accuracy results
    • Gepstein L, Hayam G, Ben-Haim SA. A novel method for nonfluoroscopic catheter-based electroanatomical mapping of the heartIn vitro and in vivo accuracy results. Circulation 1997;95: 1611-22.
    • (1997) Circulation , vol.95 , pp. 1611-1622
    • Gepstein, L.1    Hayam, G.2    Ben-Haim, S.A.3
  • 46
    • 0033766532 scopus 로고    scopus 로고
    • Assessment of left ventricular ejection fraction with quantitative gated SPECT: Accuracy and correlation with first-pass radionuclide angiography
    • Vallejo E, Dione DP, Sinusas AJ, Wackers FJ. Assessment of left ventricular ejection fraction with quantitative gated SPECT: accuracy and correlation with first-pass radionuclide angiography. J Nucl Cardiol 2000;7:461-70.
    • (2000) J. Nucl. Cardiol. , vol.7 , pp. 461-470
    • Vallejo, E.1    Dione, D.P.2    Sinusas, A.J.3    Wackers, F.J.4
  • 49
    • 0028401737 scopus 로고
    • Assessment of myocardial fatty acid metabolism with 1-
    • Geltman EM. Assessment of myocardial fatty acid metabolism with 1-. J Nucl Cardiol 1994;1(2 Pt 2):S15-22.
    • (1994) J. Nucl. Cardiol. , vol.1 , Issue.2 PART 2
    • Geltman, E.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.