The combined effects of antibacterial peptide cecropin A and anti-cancer agents on leukemia cells

Anticancer Research

Volumn 22, Issue 5, 2002, Pages 2811-2816

  Hui, Ling ^a   Leung, Keith ^a   Chen, Hueih Min ^a  

^a ACADEMIA SINICA   (Taiwan)

Author keywords

Antibacterial peptide; Anticancer agents; Cecropin A

Indexed keywords

ANTINEOPLASTIC AGENT; CECROPIN A; CYTARABINE; DOXORUBICIN; FLUOROURACIL; MERCAPTOPURINE; METHOTREXATE; VINCRISTINE;

AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; CYTOLYSIS; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LEUKEMIA CELL; MEMBRANE PERMEABILITY; PRIORITY JOURNAL;

6-MERCAPTOPURINE; AMINO ACID SEQUENCE; ANTIMICROBIAL CATIONIC PEPTIDES; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CYTARABINE; DOXORUBICIN; DRUG SCREENING ASSAYS, ANTITUMOR; FLUOROURACIL; HUMANS; LEUKEMIA; METHOTREXATE; MOLECULAR SEQUENCE DATA; TUMOR CELLS, CULTURED; VINCRISTINE;

EID: 0036765438     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Hancock REW and Lehrer R: Cationic peptides: a new source of antibiotics. TIB Tech 16: 82-88, 1998.
2. Steiner H, Bennich H, Boman HG, Engstrom A and Hultmark D: Sequence and specificity of 2 anti-bacterial proteins involved in insect immunity. Nature 292: 246-248, 1981.
3. Qu XM, Steiner H, Engstrom A, Bennich H and Boman HG: Insect immunity: isolation and structure of cecropin B and D from pupae of the Chinese oak silk moth, Antheraea perayi. Eur J Biochem 127: 219-224, 1982.
4. Morishima I, Suginaka S, Ueno T and Hirano H: Isolation and structure of cecropins, inducible antibacterial peptides, from the silkworm, Bombyx mori. Comp Biocheml Physioll B- Comp Biochemistry 95: 551-554, 1990.
5. Dickson L, Russell V and Dunn PE: A family of bacteria-regulated, cecropin D-like peptides from Manduca sexta. J Biol Chem 263: 19424-19429, 1988.
6. Hoffman JA, Hetru C and Reichhart JM: The humoral antibacterial response of Drosophila. FEBS Lett 325: 63-66, 1993.
7. Lee JY, Boman A, Sun CX, Andersson M, Jornvall H, Mutt V and Boman HG: Antibacterial peptides from pig intestine: isolation of a mammalian cecropin. Proc Natl Acad Sci USA 86: 19159-19162, 1989.
8. van Hofsten P, Faye I, Kockrum K, Lee JY, Xanthopoulos KG, Boman IA, Boman HG, Engstrom A, Andreu D and Merrified RB: Sequence and specificity of cecropins A and B. Proc Natl Acad Sci USA 82: 2240-2243, 1985.
9. Boman HG: Cecropins: Antibacterial peptides from insects and pigs. In: "Phylogenetic Perspectives in Immunity: The Insect Host Defense". edited by Hoffman JA, Janeway CA, Jr and Natori S, RG Landes Company, Chapter 1, pp3-17.
10. Moore AJ, Devine DA and Bibby MC: Preliminary experimental anticancer activity of cecropins. Peptide Res 7: 265-269, 1994.
11. Chen HM, Wang W, Smith D and Chan SC: Effects of the antibacterial peptide cecropin B and its analogs, cecropins B-1 and B-2, on liposomes, bacteria and cancer cells. Biochim Biophys Acta 1336: 171-179, 1997.
12. Cruciani RA, Barker JL, Zasloff M, Chen HC and Colamonici O: Antibiotic magainins exert cytolytic activity against transformed-cell lines through channel formation. Proc Natl Acad Sci USA 88: 3792-3796, 1991.
13. Helmerhorst EJ, Reijnders IM, van't Hof W, Veerman CI and Amerongen A VN: A critical comparison of the haemolytic and fungicidal activities of cationic antimicrobial peptides. FEBS Lett. 449: 105-110, 1999.
14. Chan SC, Yau WL, Wang W, Smith DK, Sheu F-S and Chen HM: Microscopic observations of the different morphological changes by the anti-bacterial peptides on Klebsiella pneumoniae and HL-60 leukemia cells. J Peptide Sci 4: 413-435, 1998.
15. Chan SC, Hui L and Chen HM: Enhancement of the cytolytic effect of anti-bacterial cecropin by the microvilli of cancer cells. Anticancer Res 18: 4467-4474, 1998.
16. Foye WO: Cancer Chemotherapeutic Agents. ACS Professional Reference Book, American Chemical Society, Washington, DC, 1995.
17. Merlin JL: Concepts of synergism and antagonism. Anticancer Res 4: 2315- 2320, 1994.
18. Steel GG and Peckham MJ: Exploitable mechanisms in combined radiotherapy-chemotherapy: the concept of additivity. Int J Radiation Oncology Biol Phys 5: 85-91, 1979.
19. Mishell BB and Shiigi SM: Selected Method in Cellular Immunology. San Francisco, W. H. Freeman and Company, 1980.
20. Vistica DT, Skehan P, Scudiero D, Monks A, Piffman A and Boyd MR: Tetrazolium-base assays for cellular viability: A critical examination of selected parameters affecting formazan production. Cancer Res 51: 515-2520, 1991.
21. Minna JD, Ihde DC and Glastein EJ: Leukemia: Scalpels, beams, drugs, and probes. N Engl J Med 315: 1411-1416, 1986.
22. Nooter K and Herweijer H: Multidrug resistance gene in human cancer. Bri J Cancer 63: 663-669, 1991.
23. Sotomatsu M, Yugami S-I, Shitara T and Kuroume T: Dipyridamile enhancement of drug sensitivity in acute lymphoblastic leukemia cells. Amer J Hematology 43: 251-255, 1993.
24. Edwards DA, Hanes J, Caponetti G, Hrkach J, Ben-Jebria A, Eskew ML, Mintzes J, Deaver D, Lotan N and Langer R: Larger porous particles for pulmonary drug delivery. Science 276: 1868-1871, 1997.
25. Holak TA, Engstrom A, Kraulis PJ, Lindeberg G, Bennich H, Jones TA, Gronenborn AM and Clore GM: The solution conformation of the antibacterial peptide cecropin A: A nuclear magnetic resonance and dynamical simulated annealing study. Biochemistry 27: 7620- 7629, 1988
26. Ramilotorno LV and Avramis VI: Intracellular pharmacodynamic studies of the synergistic combination of 6-mercaptopurine and cytosine arebinoside in human leukemia cell lines. Cancer Chem Phar 35: 191-199, 1995.