-
1
-
-
0011745734
-
-
(NPS Pharmaceuticals, Inc.). Calcium receptoractive cpds. US 6211244
-
Van Wagenen, B.C., Moe, S.T., Balandrin, M.F., DelMar, E.G., Nemeth, E.F. (NPS Pharmaceuticals, Inc.). Calcium receptoractive cpds. US 6211244.
-
-
-
Van Wagenen, B.C.1
Moe, S.T.2
Balandrin, M.F.3
DelMar, E.G.4
Nemeth, E.F.5
-
2
-
-
0011768853
-
-
National Institute of Diabetes & Digestive & Kidney Diseases Web Site. September 12
-
Hyperparathyroidism. National Institute of Diabetes & Digestive & Kidney Diseases Web Site. September 12, 2002.
-
(2002)
Hyperparathyroidism
-
-
-
3
-
-
0011743101
-
-
Columbia Presbyterian Medical Center Web Site. September 12, 2002
-
Columbia Presbyterian Medical Center Web Site. September 12, 2002.
-
-
-
-
4
-
-
0025922923
-
2+ and other ions as extracellular (first) messengers
-
2+ and other ions as extracellular (first) messengers. Physiol Rev 1991, 71: 371-411.
-
(1991)
Physiol Rev
, vol.71
, pp. 371-411
-
-
Brown, E.M.1
-
5
-
-
0027765508
-
2+-sensing receptor from bovine parathyroid
-
2+-sensing receptor from bovine parathyroid. Nature 1993, 366: 575-80.
-
(1993)
Nature
, vol.366
, pp. 575-580
-
-
Brown, E.M.1
Gamba, G.2
Riccardi, D.3
Lombardi, M.4
Butters, R.5
Kifor, O.6
Sun, A.7
Hediger, M.A.8
Lytton, J.9
Hebert, S.C.10
-
6
-
-
0031033870
-
Localization of calcium receptor mRNA in the adult rat central nervous system by in situ hybridization
-
Rogers, K.V., Dunn, C.K., Hebert, S.C., Brown, E.M. Localization of calcium receptor mRNA in the adult rat central nervous system by in situ hybridization. Brain Res 1997, 744: 47-56.
-
(1997)
Brain Res
, vol.744
, pp. 47-56
-
-
Rogers, K.V.1
Dunn, C.K.2
Hebert, S.C.3
Brown, E.M.4
-
7
-
-
0030781163
-
Expression of an extracellular calcium-sensing receptor in human and mouse bone marrow cells
-
House, M.G., Kohlmeier, L., Chattopadhyay, N., Kifor, O., Yamaguchi, T., Leboff, M.S., Glowacki, J., Brown, E.M. Expression of an extracellular calcium-sensing receptor in human and mouse bone marrow cells. J Bone Miner Res 1997, 12: 1959-70.
-
(1997)
J Bone Miner Res
, vol.12
, pp. 1959-1970
-
-
House, M.G.1
Kohlmeier, L.2
Chattopadhyay, N.3
Kifor, O.4
Yamaguchi, T.5
Leboff, M.S.6
Glowacki, J.7
Brown, E.M.8
-
9
-
-
0031299792
-
Cation sensing receptors in bone: A novel paradigm for regulating bone remodeling?
-
Quarles, L.D. Cation sensing receptors in bone: A novel paradigm for regulating bone remodeling? J Bone Miner Res 1997, 12: 1971-4.
-
(1997)
J Bone Miner Res
, vol.12
, pp. 1971-1974
-
-
Quarles, L.D.1
-
10
-
-
0028848215
-
Calcium-sensing receptor mutations in familial benign hypercalcemia and neonatal hyperparathyroidism
-
Pearce, S.H., Trump, D., Wooding, C. et al. Calcium-sensing receptor mutations in familial benign hypercalcemia and neonatal hyperparathyroidism. J Clin Invest 1995, 96: 2683-92.
-
(1995)
J Clin Invest
, vol.96
, pp. 2683-2692
-
-
Pearce, S.H.1
Trump, D.2
Wooding, C.3
-
11
-
-
0027787680
-
2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism
-
2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell 1993, 75: 1297-303.
-
(1993)
Cell
, vol.75
, pp. 1297-1303
-
-
Pollak, M.R.1
Brown, E.M.2
Chou, Y.H.3
Hebert, S.C.4
Marx, S.J.5
Steinmann, B.6
Levi, T.7
Seidman, C.E.8
Seidman, J.G.9
-
12
-
-
0029995936
-
Three inherited disorders of calcium sensing
-
Pollak, M.R., Seidman, C.E., Brown, E.M. Three inherited disorders of calcium sensing. Medicine (Baltimore) 1996, 75: 115-23.
-
(1996)
Medicine (Baltimore)
, vol.75
, pp. 115-123
-
-
Pollak, M.R.1
Seidman, C.E.2
Brown, E.M.3
-
13
-
-
0029985394
-
2+-sensing receptor gene cause autosomal dominant and sporadic hypoparathyroidism
-
2+-sensing receptor gene cause autosomal dominant and sporadic hypoparathyroidism. Hum Mol Genet 1996, 5: 601-6.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 601-606
-
-
Baron, J.1
Winer, K.K.2
Yanovski, J.A.3
Cunningham, A.W.4
Laue, L.5
Zimmerman, D.6
Cutler G.B., Jr.7
-
14
-
-
10144256536
-
A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calcium-sensing receptor
-
Pearce, S.H., Williamson, C., Kifor, O. et al. A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calcium-sensing receptor. New Engl J Med 1996, 335: 1115-22.
-
(1996)
New Engl J Med
, vol.335
, pp. 1115-1122
-
-
Pearce, S.H.1
Williamson, C.2
Kifor, O.3
-
15
-
-
0031042732
-
Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism
-
Gogusev, J., Duchambon, P., Hory, B., Giovannini, M., Goureau, Y., Sarfati, E., Drueke, T.B. Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism. Kidney Int 1997, 51: 328-36.
-
(1997)
Kidney Int
, vol.51
, pp. 328-336
-
-
Gogusev, J.1
Duchambon, P.2
Hory, B.3
Giovannini, M.4
Goureau, Y.5
Sarfati, E.6
Drueke, T.B.7
-
16
-
-
0033935152
-
A calcimimetic agent lowers plasma parathyroid hormone levels in patients with secondary hyperparathyroidism
-
Goodman, W.G., Frazao, J.M., Goodkin, D.A., Turner, S.A., Liu, W., Coburn, J.W. A calcimimetic agent lowers plasma parathyroid hormone levels in patients with secondary hyperparathyroidism. Kidney Int 2000, 58: 436-45.
-
(2000)
Kidney Int
, vol.58
, pp. 436-445
-
-
Goodman, W.G.1
Frazao, J.M.2
Goodkin, D.A.3
Turner, S.A.4
Liu, W.5
Coburn, J.W.6
-
17
-
-
0011711890
-
Pharmacokinetics (PK) of calcimimetic AMG 073 in secondary hyperparathyroidism (SHPT)
-
Abst PIII-107
-
Wang, B., Osborn, K., Blaisdell, P., Brenner, R., Turner, S., Laycock, J., Mooney, J., Ghobarah, H., Arends, R. Pharmacokinetics (PK) of calcimimetic AMG 073 in secondary hyperparathyroidism (SHPT). Clin Pharmacol Ther 2001, 69(2): Abst PIII-107.
-
(2001)
Clin Pharmacol Ther
, vol.69
, Issue.2
-
-
Wang, B.1
Osborn, K.2
Blaisdell, P.3
Brenner, R.4
Turner, S.5
Laycock, J.6
Mooney, J.7
Ghobarah, H.8
Arends, R.9
-
18
-
-
0000854841
-
An evaluation of the calcimimetic AMG 073 in patients with hypercalcemia and primary hyperparathyroidism (PHPT)
-
Abst SA462
-
Shoback, D.M., Firek, A.F., Mims, R.B., Binder, T.A., Graves, T., Turner, S.A., Peacock, M. An evaluation of the calcimimetic AMG 073 in patients with hypercalcemia and primary hyperparathyroidism (PHPT). J Bone Miner Res 2001, 16(Suppl. 1): Abst SA462.
-
(2001)
J Bone Miner Res
, vol.16
, Issue.SUPPL. 1
-
-
Shoback, D.M.1
Firek, A.F.2
Mims, R.B.3
Binder, T.A.4
Graves, T.5
Turner, S.A.6
Peacock, M.7
-
19
-
-
0001620561
-
Calcimimetic AMG 073 normalizes total serum calcium in patients with primary hyperparathyroidism
-
Sept 22-26, Toronto, Abst F116
-
Shoback, D.M., Bilezikian, J., Binder, T.A., Graves, T., Turner, S.A., Peacock, M. Calcimimetic AMG 073 normalizes total serum calcium in patients with primary hyperparathyroidism. 22nd Annu Meet Am Soc Bone Miner Res (ASBMR) (Sept 22-26, Toronto) 2000, Abst F116.
-
(2000)
22nd Annu Meet Am Soc Bone Miner Res (ASBMR)
-
-
Shoback, D.M.1
Bilezikian, J.2
Binder, T.A.3
Graves, T.4
Turner, S.A.5
Peacock, M.6
-
20
-
-
0001498322
-
The calcimimetic AMG 073 reduces serum calcium (Ca) in patients with primary hyperparathyroidism (PHPT)
-
Abst 1106
-
Peacock, M., Shoback, D.M., Greth, W.E., Binder, T.A., Graves, T., Brenner, R.M., Turner, S.A., Marcus, R. The calcimimetic AMG 073 reduces serum calcium (Ca) in patients with primary hyperparathyroidism (PHPT). J Bone Miner Res 2001, 16(Suppl 1): Abst 1106.
-
(2001)
J Bone Miner Res
, vol.16
, Issue.SUPPL. 1
-
-
Peacock, M.1
Shoback, D.M.2
Greth, W.E.3
Binder, T.A.4
Graves, T.5
Brenner, R.M.6
Turner, S.A.7
Marcus, R.8
-
21
-
-
0011711579
-
Long-term treatment with the calcimimetic AMG 073 in patients with primary hyperparathyroidism (PHPT)
-
June 1922, San Francisco, Abst OR21-1
-
Peacock, M., Bilezekian, J.P., Turner, S.A., Guo, M.D., McCary, L.C., Koenig, K.G., Shoback, D.M. Long-term treatment with the calcimimetic AMG 073 in patients with primary hyperparathyroidism (PHPT). 84th Annu Meet Endocr Soc (June 1922, San Francisco) 2002, Abst OR21-1.
-
(2002)
84th Annu Meet Endocr Soc
-
-
Peacock, M.1
Bilezekian, J.P.2
Turner, S.A.3
Guo, M.D.4
McCary, L.C.5
Koenig, K.G.6
Shoback, D.M.7
-
22
-
-
0036208986
-
The calcimimetic agent AMG 073 lowers plasma parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism
-
Goodman, W.G., Hladik, G.A., Turner, S.A., Blaisdell, P.W., Goodkin, D.A., Liu, W., Barri, Y.M., Cohen, R.M., Coburn, J.W. The calcimimetic agent AMG 073 lowers plasma parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism. J Am Soc Nephrol 2002, 13: 1017-24.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1017-1024
-
-
Goodman, W.G.1
Hladik, G.A.2
Turner, S.A.3
Blaisdell, P.W.4
Goodkin, D.A.5
Liu, W.6
Barri, Y.M.7
Cohen, R.M.8
Coburn, J.W.9
-
23
-
-
0000795191
-
Single doses of the calcimimetic AMG 073 reduce parathyroid hormone levels in a dose dependent manner in hemodialysis patients with secondary hyperparathyroidism
-
Abst A3027
-
Coburn, J.W., Barri, Y.M., Turner, S.A., Blaisdell, P.W., Goodkin, D.A., Liu, W., Goodman, W.G. Single doses of the calcimimetic AMG 073 reduce parathyroid hormone levels in a dose dependent manner in hemodialysis patients with secondary hyperparathyroidism. J Am Soc Nephrol 2000, 11: Abst A3027.
-
(2000)
J Am Soc Nephrol
, vol.11
-
-
Coburn, J.W.1
Barri, Y.M.2
Turner, S.A.3
Blaisdell, P.W.4
Goodkin, D.A.5
Liu, W.6
Goodman, W.G.7
-
24
-
-
0002452676
-
Multiple doses of the calcimimetic AMG 073 reduce plasma parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism (SHPT)
-
Abst A3039
-
Goodman, W.G., Hladik, G.A., Turner, S.A., Blaisdell, P.W., Goodkin, D.A., Liu, W., Cohen, R.M., Coburn, J.W. Multiple doses of the calcimimetic AMG 073 reduce plasma parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism (SHPT). J Am Soc Nephrol 2000, 11: Abst A3039.
-
(2000)
J Am Soc Nephrol
, vol.11
-
-
Goodman, W.G.1
Hladik, G.A.2
Turner, S.A.3
Blaisdell, P.W.4
Goodkin, D.A.5
Liu, W.6
Cohen, R.M.7
Coburn, J.W.8
-
25
-
-
0011741213
-
Short-term treatment of secondary hyperparathyroidism (SHPT) with the calcimimetic agent AMG 073
-
Oct 13-17, San Francisco, Abst A3992
-
Drueke, T., Cunningham, J., Goodman, W.G., Horl, W.H., Braun, J., Chen, M.-G., McCary, L.C., Steinhauslin-Jeanrenaud, F., Turner, S.A., Ritz, E. Short-term treatment of secondary hyperparathyroidism (SHPT) with the calcimimetic agent AMG 073. ASN/ISN World Congr Nephrol (Oct 13-17, San Francisco) 2001, Abst A3992.
-
(2001)
ASN/ISN World Congr Nephrol
-
-
Drueke, T.1
Cunningham, J.2
Goodman, W.G.3
Horl, W.H.4
Braun, J.5
Chen, M.-G.6
McCary, L.C.7
Steinhauslin-Jeanrenaud, F.8
Turner, S.A.9
Ritz, E.10
-
26
-
-
0001276085
-
The calcimimetic AMG 073 reduces parathyroid hormone (PTH) phosphorus (P), and calcium X phosphorus product (Ca X P) in patients with ESRD and secondary hyperparathyroidism (SHPT)
-
Abst A3052
-
Lindberg, J.S., Moe, S.M., Goodman, W.G., Coburn, J.W., Turner, S.A., Blaisdell, P.W., McCary, L.C., Brenner, R.M., Liu, W., Martin, K.J. The calcimimetic AMG 073 reduces parathyroid hormone (PTH) phosphorus (P), and calcium X phosphorus product (Ca X P) in patients with ESRD and secondary hyperparathyroidism (SHPT). J Am Soc Nephrol 2000, 11: Abst A3052.
-
(2000)
J Am Soc Nephrol
, vol.11
-
-
Lindberg, J.S.1
Moe, S.M.2
Goodman, W.G.3
Coburn, J.W.4
Turner, S.A.5
Blaisdell, P.W.6
McCary, L.C.7
Brenner, R.M.8
Liu, W.9
Martin, K.J.10
-
27
-
-
0011768630
-
The calcimimetic AMG 073 reduces PTH and CaxP in patients with secondary hyperparathyroidism (SHPT)
-
Oct 13-17, San Francisco, Abst A4027
-
Quarles, L.D., Sherrard, D.J., Adler, S., Rosansky, S.J., McCary, L.C., Brenner, R.M., Liu, W., Turner, S.A., Bushinsky, D.A. The calcimimetic AMG 073 reduces PTH and CaxP in patients with secondary hyperparathyroidism (SHPT). ASN/ISN World Congr Nephrol (Oct 13-17, San Francisco) 2001, Abst A4027.
-
(2001)
ASN/ISN World Congr Nephrol
-
-
Quarles, L.D.1
Sherrard, D.J.2
Adler, S.3
Rosansky, S.J.4
McCary, L.C.5
Brenner, R.M.6
Liu, W.7
Turner, S.A.8
Bushinsky, D.A.9
-
28
-
-
4243953360
-
-
Amgen Web Site August 29
-
Product pipeline. Amgen Web Site August 29, 2002.
-
(2002)
Product pipeline
-
-
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