Overexpression of the GABAA receptor ε subunit results in insensitivity to anaesthetics

Neuropharmacology

Volumn 43, Issue 4, 2002, Pages 662-668

  Thompson, S A ^a   Bonnert, T P ^a   Cagetti, E ^a   Whiting, P J ^a   Wafford, Keith A ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

Anaesthetics; GABAA receptors; Overexpression; Recombinant; Xenopus oocytes; subunit

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 5 ALPHA PREGNAN 3 ALPHA OLONE; AMINO ACID; ANESTHETIC AGENT; COMPLEMENTARY DNA; DIMETHYL SULFOXIDE; DRUG RECEPTOR; ELTANOLONE; ETOMIDATE; PENTOBARBITAL; PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG POTENTIATION; DRUG SENSITIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOLECULAR CLONING; OOCYTE; PRIORITY JOURNAL; PROMOTER REGION; RNA TRANSLATION; WESTERN BLOTTING; XENOPUS;

ANESTHETICS; ANESTHETICS, INTRAVENOUS; ANIMALS; BLOTTING, WESTERN; CELL LINE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ETOMIDATE; FEMALE; GABA ANTAGONISTS; GABA MODULATORS; GAMMA-AMINOBUTYRIC ACID; HUMANS; OOCYTES; PENTOBARBITAL; PICROTOXIN; PROTEIN ENGINEERING; RECEPTORS, GABA-A; STEROIDS; TRANSFECTION; XENOPUS LAEVIS;

EID: 0036753724     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00162-4     Document Type: Article

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