Antitumor activity of a water soluble proteoglycan isolated from Sarcodon aspratus (Berk.) S. Ito

Korean Journal of Pharmacognosy

Volumn 33, Issue 3, 2002, Pages 224-229

  Moon, Young Hee ^a   Woo, Eun Rhan ^a   Park, Young Jun ^a  

^a Chosun University   (South Korea)

Author keywords

Antitumor activity; Proteoglycan; Sarcodon aspratus; Sarcoma 180

Indexed keywords

AMINO ACID; ANTINEOPLASTIC AGENT; ARABINOSE; GALACTOSE; GLUCOSE; MANNOSE; PROTEOGLYCAN; RHAMNOSE; SAP A; SAP B; SARCODON ASPRATUS EXTRACT; SUGAR; UNCLASSIFIED DRUG; XYLOSE;

AMINO ACID COMPOSITION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG ISOLATION; DRUG POTENCY; KOREA; MOLECULAR WEIGHT; MOUSE; NONHUMAN; SARCOMA; TRADITIONAL MEDICINE;

EID: 0036751467     PISSN: 02533073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Chihara, G., Hamuro, J., Maeda, Y.Y., Arai, Y., and Fukuoka, F.(1970) Antitumor polysaccharide derived chemically from naural glucan (Pachyman). Nature. 225: 943-949.
2. Fujii, T, Maeda, H., Suzuki, F., and Ishida, N.(1980) Isolation and characterization of a new antitumor polysaccharide. KS-2. extracted from culture mycelia of Lentinus edodes. J. Antibiotics. 31: 376-381.
3. Kim, D.H., Bae, E.A., Jang, I.S., and Han, M.J.(1996) Anti- Helicobacter pylori activity of Mushrooms, Arch. Pharm. Res. 19: 447-449.
4. Kim, H.R., Shim, M.J., Kim, J.W., Kim, H.W., Lee, C.O., Chung, K.S., Shim, M.J., and Kim, B.K.(1983) Studies on constituents of the higher fungi of Korea (XXXVII), antitumor components of Armillariella mella. Kor. J. Mycol. 11: 151-157.
5. Suzuki, I., Itanti, T, Ohno, N., Oikawa, S., Sato, K., Miyazaki, T, and Yadomae, T. (1984) Antitumor activity of a polysaccharide fraction extracted from cultured fruiting bodies of Grifola frondosa. J. Pharm. Dyn. 7: 492-500.
6. Ohno, N., Shinohara, H., and Yadomae, T. (1986) Physicochemical properties and immunomodulating activities of hot water extract from sclerotia of Sclerotinia sclerotiorum IFO 9395. Chem. Pharm. Bull. 34: 5071-5078.
7. Judith, G.G., Paul, W.K., and Steven, B.M.(1984) Inter- leukin-1 mediated induction of k-light chain synthesis and surface immunoglobulin expression on pre B cells. J. Immunol. 132: 223-230.
8. Kim, B.K., Park, E.K., and Shim, M.J. (1979) Antineoplastic activities of Coriolus versicolor, Pleurotus ostreatus and Lentinus edodes. Arch. Pharm. Res. 2: 145-151.
9. Min, H.K., Choi, E.C., and Kim, B.K.(1980) Studies on the constituents of the higher fungi of Korea, components of Microporus affinis. Kor. J. Mycol. 8: 13-19.
10. Lee, C.O., Choi, E.C., and Kim, B.K. (1981) Studies on the antitumor components of Korean basidiomycetes (IV), antitumor components of Naematoloma fasciculare (Fr.) Karst. Arch. Pharm. Res. 4: 117-122.
11. Kim, J.S., Choi, E.C., Kim, H.R., Lee, C.O., Chung, K.S., Shim, M.J., and Kim, B. K.(1983) Studies on constituents of the higher fungi of Korea(XXXVII), antitumor components of Armillariella. Kor. J. Mycol. 11: 151-157.
12. Kim, S.H., Woo, M.S., and Kim, B.K.(1982) Antitumor components extracted from the carpophores and cultured mycelia of Laccaria laccata. Kor. J. Mycol. 10: 155-163.
13. Chung, K.S., and Kim, B.K. (1985) Studies on antitumor constituents of Pluteus cervinus. Seoul Univ. J. Pharm. Sci. 10: 1-18.
14. Jim, M.R., Jung, K.S., and Kim, B.K. (1998) Differentical antitumor activities of the proteoglycans from the mycelium of Lentinus lepideus. Yakhak Hoeji. 42: 480-486.
15. Lee, TK. (1986) Purification and some chracteristics of the proteolytic enzyme in fruitbody of neungee (Sarcodon aspratus (Berk). S. Ito.). J. Korean Soc. Food nutr. 17: 276-282.
16. Lee, TK., Eun, J.S., Yang, J.H., Jo, D.Y., and Yang, H.C. (1989) Studies on higher fungi in Korea(III), purification and stability of proteolytic enzyme Sarcodon aspratus (Berk.) S. Ito. J. Kor. Pharm. Sci. 19: 81-86.
17. Eun, J.S., Yang, J.H., Cho, D.Y., and Lee, T(1988) Studies on higher fungi in Korea(I), Activity of proteolytic ezyme from Sarcodon asoratus(Berk.) S. Ito. J. Kor. Pharm. Sci. 19: 125-131.
18. Uhm, T.B., Ryu, K.S., Kim, M.K., and You, J.S. (1991) Characterization of a serine protease from neungee [Sarcodon aspratus(Berk.)S. Ito]. J. Korean Soc. Food Nutr. 120: 35-39.
19. Swada, J.(1964) Studies on the acid-protease of Paecilomyces varioti Bainer TPR-220. Part II, some enzymatic properties of the crystalline acid-protease. Agr. Biol. Chem. 28: 348-354.
20. Park, W.H. (1986) Studies on enzymes of the higher fungi of Korea(I), identification of protease in Sarcodon aspratus. Kor. J. Mycol. 14: 25-30.
21. Park, W.H. (1983) Studies on components of Sarcodon aspratus(II), Kor. J. Mycol. 11: 159-162.
22. Maruyama, H., Yamazaki, K., Murofushi, S., Konda, C., and Ikekawa, T. (1989) Antitumor activity of Sarcodon aspratus (Berk.) S. Ito and Ganoderma lucidum(Fr.) Karst. J. pharmacobio-pym. 12: 118-123.
23. Park, W.H. (1983) Studies on components of Sarcodon aspratus(I). Kor. J. Mycol. 11: 85-89.
24. Redier, D.D., Brown, R.S., Weingerger, S., Kenny, J., and Bailey, J. (1998) Unknown peptide sequencing using matrix-assisted laser desorption/ionization and in source decay. Anal. Chem. 70: 1214-1222.
25. Karas, M., and Hillenkamp, F.(1988) Laser desorption ionization of proteins with molecular masses exceeding 10000 daltons. Anal. Chem. 60: 2299-2301.
26. Chaplin, M.F.(1994) In carbohydrate analysis, Oxford University press, London, pp.6-7, 32-45.
27. Maeda, Y.Y., and Chihara, G. (1973) Periodical considerationon the establishment of antitumor action in host and activation of peritoneal exudate cells by lentinan. Gann. 64:351-357.