The helper T lymphocyte precursor (HTLp) frequency does not predict outcome after HLA-identical sibling donor G-CSF-mobilised peripheral blood stem cell transplantation

Bone Marrow Transplantation

Volumn 30, Issue 6, 2002, Pages 341-346

  Healey, G ^a   Schwarer, A P ^a  

^a ALFRED HOSPITAL   (Australia)

Author keywords

GVHD; Helper T lymphocyte precursor frequency; PBSC transplantation

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; ALLOTRANSPLANTATION; ARTICLE; ASSAY; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DILUTION; DONOR; FEMALE; GRAFT VERSUS HOST REACTION; HELPER CELL; HEMATOLOGIC DISEASE; HLA MATCHING; HUMAN; MALE; MORTALITY; PREDICTION; PRIORITY JOURNAL; PROLYMPHOCYTE; RECIPIENT; SIBLING; STEM CELL MOBILIZATION; STEM CELL TRANSPLANTATION; TREATMENT OUTCOME; BLOOD DISEASE; CYTOLOGY; IMMUNOLOGY; ISOGRAFT; LYMPHOCYTE COUNT; METHODOLOGY; MIDDLE AGED; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; PROGNOSIS; PROSPECTIVE STUDY; RECURRENT DISEASE; SURVIVAL RATE;

ADULT; FEMALE; GRAFT VS HOST DISEASE; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL MOBILIZATION; HUMANS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; PROGNOSIS; PROSPECTIVE STUDIES; RECURRENCE; SIBLINGS; SURVIVAL RATE; T-LYMPHOCYTES, HELPER-INDUCER; TRANSPLANTATION, HOMOLOGOUS; TRANSPLANTATION, ISOGENEIC;

EID: 0036749945     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1703638     Document Type: Article

References (30)

1. Gratwohl A, Hermans J, Apperly J et al. Acute graft-versus-host disease: grade and outcome in patients with chronic myelogenous leukemia. Blood 1995; 86: 813-818.
2. DeGast GC, Mickelson EM, Beatty PG et al. Mixed leukocyte culture reactivity and graft-versus-host disease in HLA-identical marrow transplantation for leukemia. Bone Marrow Transplant 1992; 9: 87-90.
3. Bagot M, Mary JY, Heslan M. The mixed epidermal cell lymphocyte-reaction is the most predictive factor of acute graft-versus-host disease in bone marrow graft recipients. Br J Haematol 1988; 70: 403-409.
4. Vogelsang GB, Hess, AD, Berkman AW et al. An in vitro predictive test for graft versus host disease in patients with genotypic HLA-identical bone marrow transplants. New Engl J Med 1985; 313: 645-650.
5. Dickinson AM, Sviland L, Wang XN et al. Predicting graft-versus-host disease in HLA-identical bone marrow transplants. Transplantation 1998; 66: 857-863.
6. Kaminski E, Hows J, Man S et al. Prediction of graft versus host disease by frequency analysis of cytotoxic T cells after unrelated donor bone marrow transplantation. Transplantation 1989; 48: 608-613.
7. Schwarer AP, Jiang YZ, Deacock S et al. Comparison of helper and cytotoxic anti-recipient T cell frequencies in unrelated bone marrow transplantation. Transplantation 1994; 58: 1198-1203.
8. Van Der Meer A, Allebes WA, Voorter CEM et al. Helper and cytotoxic T cell precursor frequencies are not predictive for development of acute graft-versus-host-disease after partially T cell-depleted HLA-identical sibling BMT. Bone Marrow Transplant 1998; 22: 1049-1055.
9. Keever-Taylor CA, Passweg J, Kawanishi Y et al. Association of donor-derived host-reactive cytolytic and helper T cells with outcome following alternative donor T cell-depleted bone marrow transplantation. Bone Marrow Transplant 1997; 19: 1001-1009.
10. Pei J, Martin PJ, Longton G et al. Evaluation of pretransplant donor anti-recipient cytotoxic and helper T lymphocyte responses as correlates of acute graft-vs.-host disease and survival after unrelated marrow transplantation. Biol Blood Marrow Transplant 1997; 3: 142-149.
11. Wang XN, Taylor PR, Skinner R et al. T-cell frequency analysis does not predict the incidence of graft-versus-host disease in HLA-matched sibling bone marrow transplantation. Transplantion 2000; 70: 488-493.
12. Weston LE, Geczy AF, Farrell C. Donor helper T-cell frequencies as predictors of acute graft-versus-host disease in bone marrow transplantation between HLA-identical siblings. Transplantion 1997; 64: 836-841.
13. Schwarer AP, Jiang YZ, Brookes PA et al. Frequency of anti-recipient alloreactive helper T-cell precursors in donor blood and graft-versus-host disease after HLA-identical sibling bone-marrow transplantation. Lancet 1993; 341: 203-205.
14. Russell CA, Heilmann C, Madsen HO et al. The predictive value of helper T lymphocyte precursor frequencies for graft-versus-host disease and graft-versus-leukaemia effects in allogeneic bone marrow transplantation. Bone Marrow Transplant 2001; 27: 949-958.
15. Winandy M, Lewalle P, Deneys V et al. Pretransplant helper T-lymphocyte determination in bone marrow donors: acute graft-versus-host-disease prediction and relation with long-term survival. Br J Haematol 1999; 105: 288-294.
16. Lachance S, Le Gouvello S, Roudot F et al. Predictive value of host-specific donor helper T-cell precursor frequency for acute graft-versus-host-disease and relapse in HLA-identical siblings receiving allogeneic bone marrow transplantation for hematological malignancies. Transplantation 1997; 64: 1147-1152.
17. Theobald M, Nierle T, Bunjes D et al. Host-specific interleukin-2-secreting donor T-cell precursors as predictors of acute graft-versus-host disease in bone marrow transplantation between HLA-identical siblings. New Engl J Med 1992; 327: 1613-1617.
18. Cutler C, Giri S, Jeyapalan S et al. Acute and chronic graft-versus-host disease after allogeneic peripheral-blood stem-cell and bone marrow transplantation: a meta-analysis. J Clin Oncol 2001; 19: 3685-3691.
19. Blaise D, Kuentz M, Fortanier C et al. Randomized trial of bone marrow transplantation versus lenograstim-primed blood cell allogeneic transplantation in patients with early-stage leukemia: a report from the Societe Francaise de Greffe de Moelle. J Clin Oncol 2000; 18: 537-546.
20. Bensinger WI, Martin PJ, Storer B et al. Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers. New Engl J Med 2001; 344: 175-181.
21. Sloand EM, Kim S, Maciejewski JP et al. Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lymphocytes in vitro and in vivo. Blood 2000; 95: 2269-2274.
22. Arpinati M, Green CL, Heimfeld S et al. Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells. Blood 2000; 95: 2484-2490.
23. Fowler DH, Kurasawa K, Husebekk A et al. Cells of Th2 cytokine phenotype prevent LPS-induced lethality during murine graft-versus-host reaction. J Immunol 1994; 152: 1004-1013.
24. Rowings PA, Przepiorka D, Klein JP et al. IBMTR severity index for grading acute graft-versus-host-disease: retrospective comparison with Glucksberg grade. Br J Haematol 1997; 97: 855-864.
25. Ferrara JL, Deeg HJ. Graft-versus-host-disease. New Engl J Med 1991; 324: 667-674.
26. Fazekas de St. Groth S. The evaluation of limiting dilution assays. J Immunol Methods 1982; 49: R11-R23.
27. Taswell C. Limiting dilution assays for the determination of immunocompetent cell frequencies. J Immunol 1981; 126: 1614-1619.
28. Pan L, Delmonte J, Jalonen CK et al. Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease. Blood 1995; 86: 4422-4429.
29. Zeng D, Dejbakhsh-Jones S, Strober S. Granulocyte colony-stimulating factor reduces the capacity of blood mononuclear cells to induce graft-versus-host disease: impact on blood progenitor cell transplantation. Blood 1997; 90: 453-463.
30. Imami N, Brookes PA, Lombardi G et al. Association between interleukin-4-producing T lymphocyte frequencies and reduced risk of graft-versus-host disease. Transplantation 1998; 65: 979-988.