On prophylaxis and treatment of radition-induced dermatitis and mucositis;Zur prophylaxe und therapie der radiodermatitis und radiomucositis

H+G Zeitschrift fur Hautkrankheiten

Volumn 77, Issue 9, 2002, Pages 418-423

  Wollina, U ^a   Christen, N ^a   Kostler E ^a   Schorcht, J ^a  

^a ACADEMIC TEACHING HOSPITAL DRESDEN FRIEDRICHSTADT   (Germany)

Author keywords

Prevention; Radio mucositis; Radiodermatitis; Treatment

Indexed keywords

ALPHA TOCOPHEROL; ANTIHISTAMINIC AGENT; CYTOKINE; DEXPANTHENOL; GAMMA INTERFERON; GROWTH FACTOR; PENTOXIFYLLINE; STEROID;

ARTICLE; CANCER RADIOTHERAPY; DISEASE CLASSIFICATION; GERMANY; HUMAN; MUCOSA INFLAMMATION; PROPHYLAXIS; QUALITY OF LIFE; RADIATION DERMATITIS; RADIATION INJURY; RADIATION MUCOSITIS;

EID: 0036748850     PISSN: 03010481     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1439-0353.2002.02103.x     Document Type: Article

References (69)

1. Adamietz, I.A., R. Rahn, H.D. Böttcher, V. Schäfer, K. Reimer & W. Fleischer (1998): Prävention der Radiochemotherapie-induzierten Mucositis. Strahlenther. Onkol. 174, 149-155.
2. Blackmar, A. (1997): Radiation-induced skin alterations. Medsurg. Nurs. 6, 172-175.
3. Boot-Vickers & M., K. Eaton (1999): Skin care for patients receiving radiotherapy. Prof. Nurse 14, 706-708.
4. Bostrom, A., H. Lindman, C. Swartling, B. Berne & J. Bergh (2001): Potent corticosteroid cream (mometasone furoate) significantly reduces radiation dermatitis: results from a double-blind randomized study. Radiother. Oncol. 59, 257-265.
5. Campbell, J. & C. Lane (1996): Developing a skin-care protocol in radiotherapy. Prof. Nurse 12, 105-108.
6. Camridge, R. & A. Price (2001): Characterizing the phenomenon of radiation recall dermatitis. Radiother. Oncol. 59, 237-245
7. Carrasco, L., C. Moreno, M.A. Pastor, M.J. Izquierdo, C. Farina, L. Martin, O.P. Sangueza & L. Requena (2001): Postirradiation pseuosclerodermatous panniculitis. Am. J. Dermatopathol. 23, 283-287.
8. Dodd, M.J., C. Maskowski, G.H. Shiba, S.L. Dibble, D. Greenspan, L. MacPhail, S.M. Paul & P. Larson (1999): Risk factors for chemotherapy-induced oral mucositis: dental appliances, oral hygiene, previous oral lesions, and history of smoking. Cancer Invest. 17, 278-284.
9. Dörr, W., J.S. Zimmermann, M.H. Seegenschmiedt (2000): Nebenwirkungen in der Radio-onkologie. Klinisches Kompendium Urban & Vogel, München.
10. Fenig, E., B. Brenner, A. Katz, J. Sulkes, M. Lapidot, J. Schachter, H. Malik, A. Sulkes & H. Gutman (2001): Topical Biafine and Lipiderm for the prevention of radiation dermatitis: a randomized prospective trial. Oncol. Rep 8, 305-309.
11. Fischer, M., J. Wohlrab & W. Marsch (2001): Crux medicorum ulcerated radiation-induced fibrosis - successful therapy with pentoxyfylline and vitamin E. Eur. J. Dermatol. 11, 38-40.
12. Fisher, J., C. Scott, R. Stevens, B. Marconi, L. Champion, G.M. Freedman, F. Asrari, M.V. Pilepich, J.D. Gagnon & G. Wong (2000): Randomized phase III study comparing Best Supportive Care to Biafine as a prophylactic agent for radialion-induced skin toxicity for women undergoing breast irradiation. Radiation Therapy Oncology Group (RTOG) 97-13. Int. J. Radiat. Oncol. Biol. Phys. 48, 1307-1310.
13. Gehring, W. & M. Gloor (2000): Die Bedeutung von topisch appliziertem Dexpanthenol für die epidermale Barrierefunktion und die Hydratation des Stratum corneum. Arzneim Forsch/Drug Res. 50(11), 659-663,
14. Gehring, W. & M. Gloor (2001): Der Effekt von Dexpanthenol bei experimentell geschädigter Haut. Z. Hautkrankh. 76, 212-218.
15. Girard, P., A. Berand, C. Goujou, A. Sirvent, J.-L. Foyatier, B. Alleaume & R. de Bony (1998). Effect of Bepanthen" Ointment on the graft-donor site wound-healing model: double-blind biometrical and clinical study, with assessment by the patient, versus the vehicle. Nouv. Dermatol. 17, 559-570.
16. Girard, P., C. Goujou, L. Violin, R. de Bony, J.L. Foyatier (1997): A double-blind biometrical, histological, clinical and patient evaluation pilot study of the effect of Bepanthen" Ointment versus excipient using a skin graft donor site as a wound healing model. Nouv. Dermatol. 16, 266-275.
17. Gobbels, M. & D. Gross D (1996): Klinische Studie zur Wirksamkeit einer dexpanthenolhaltigen künstlichen Tränenflüssigkeit (Siccaprotect) in der Behandlung trockener Augen Klin. Monatsbl. Augenheilkd. 209, 84-88.
18. Goldschmidt, H. & W.K. Sherwin (1996): Radio-dermatitis and other sequefae of ionizing radiation. In: Clinical Dermatology. Ed.: D.J. Demis. vol. 4, pp. 119-8.1-19-8.18, Lippincott-Raven, Philadelphia, New York.
19. Gorodetsky, R., A. Andriessen, I. Polyansky & A. Vexler (1999): Measurement of breast skin viscoelasticity and a pilot study of the potential radioprotective effect of a zinc-based cream. J. Wound Care 8, 514-518.
20. Gottlöber, P., G. Krahn & R.U. Peter (2000): Das kutane Strahlensyndrom: Klinik, Diagnostik und Therapie. Hautarzt 51, 567-574.
21. Gottlöber, P., M. Steinert, W. Bahren, L. Weber, H. Gerngross & R.U. Peter (2001): Interferon-gamma in 5 patients with cutaneous radiation syndrome after radiation therapy Int. J. Radiat. Oncol. Biol. Phys. 50, 159-166.
22. Goujou, C., B. Alleaume, R. de Bony & P. Girard (1997): Bépanthène" Onguent. Etude pilote comparative, randomisèe, en simple insu, evaluant L'efficacité et la tolërance du produit chez des sujets présentant une sécheresse bilatérale des mains, Réalitès Therapeutiques en Dermato-Vénérologie 66, 47-53.
23. Hasenau, C., B.P. Clasen & D. Roettger (1988): Use of standardized oral hygiene in the prevention and therapy of mucositis in patients treated with radiochemotherapy of head and neck neoplasms. Laryngol. Rhinol. Otol. 67, 576-579.
24. Hom, D.B., G. Adams, M. Koreis & R. Maisel (1999): Choosing the optimal wound dressing for irradiated soft tissue wounds. Otolaryngol. Head Neck Surg 121, 591-598.
25. Hosemann, W., U. Gode, F. Langer & M.E. Wigand (1991): Experimental studies of wound healing in the paranasal sinuses. II. Spontaneous wound healing and drug effects in a standardized wound model. HNO 39, 48-54.
26. Johnson, J.T. (2001): Prevention of radiation-induced mucositis. Curr. Oncol. Rep. 3, 56-58.
27. Kehrl, W. & U. Sonnemann (1998): Dexpanthenol spray as an effective therapeutic principle for treatment of rhinitis sicca anterior. Laryngorhinootologie 77, 506-512.
28. Kelly, L.D. (1999): Nursing assessment and patient management. Semin. Oncol. Nurs. 15, 282-291.
29. Kouvaris, J.R., V.E. Kouloulias. G.A. Plataniotis, E.J. Balafouta & L. Vlahos (2001): Dermatitis during radiation for vulvar carcinoma: prevention and treatment with granulocyte-macrophage colony-stimulating factor impregnated gauze. Wound Repair Regen. 9, 187-193.
30. Lavery, B.A. (1995): Skin care during radiotherapy: a survey of UK practice. Clin. Oncol (R. Coll. Radiol.) 7, 184-187.
31. Levy-Polack, M.P., P. Sebelli & N.L. Polack (1998): Incidence of oral complications and application of a preventive protocol in children with acute leukemia. Spec. Care Dentist 18, 189-193.
32. Lokkevik, E., E. Skovlund, J.B. Reitan, E. Hannisdal & G. Tanum (1996): Skin treatment with bepanthen cream versus no cream during radiotherapy - a randomized controlled trial. Acta Oncol. 35, 1021-1026.
33. Lorette, G. & L. Machet (2001): Radiation-induced skin toxicities: prevention, treatment. Cancer Radiother. 5 [Suppl 1], 116s-120s.
34. Maiche, A., O.P. Isokangas & P. Grohn (1994): Skin protection by sucralfate cream during electron beam therapy. Acta Oncol. 33, 201-203.
35. Mak, S.S., A. Molassiotis, W.M. Wan, I.Y. Lee & E.S. Chan (2000): The effects of hydrocolloid dressing and gentian violet on radiation-induced moist desquamation wound healing. Cancer Nurs. 23, 220-229.
36. Mose, S., I.A. Adamietz, F. Saran, C. Thilmann, R. Heyd, R. Knecht & H. D. Böttcher (1997): Can prophylactic application of immunoglobulin decrease radiotherapy-induced oral mucositis? Am. J. Clin. Oncol. 20, 407-411.
37. Olsen, D.L., W. Raub Jr., C. Bradley, M. Johnson, J.L. Macias, V. Love & A. Markoe (2001): The effect of aloe vera gel/mild soap versus mild soap alone in preventing skin reactions in patients undergoing radiation therapy. Oncol. Nurs. Forum 28, 543-547.
38. Orfanos, C.E. & C. Garbe (2001): Therapie der Hautkrankheiten. 2. Auflage, S. 63, Springer-Verlag, Berlin, Heidelberg, New York.
39. Panizzon, R.G. & H. Goldschmidt (1991): Radialion reactions and sequelae. In: Modern Dermatologic Radiation Therapy. Eds.: H. Goldschmidt & R.G. Panizzon, pp. 25-36, Springer, New York.
40. Panizzon, R.G. & R.-O. Mirimanoff (2001): Hautpflege bei Tiefenbestrahlung. Hautarzt 52, 150.
41. Peter, R.U. (1996a): Pathophysiologie kulaner Strahlenreaktionen. In: Strahlentherapie dermatologischer Erkrankungen. Hrsg.: R.U. Peter & G. Plewig, S. 7-24, Blackwell-Wissenschafts-verlag, Berlin, Wien.
42. Peter, R.U. (1996b): Therapie kutaner Strahlenreaktionen nach Strahlentherapie. In: Strahlen-therapie dermatologischer Erkrankungen. Hrsg.: R.U. Peter & G. Plewig, S. 218-226, Blackwell-Wissenschaftsverlag, Berlin, Wien.
43. Peter, R.U., P. Gottlöber, N. Nadeshina, G. Krahn, O. Braun-Falco & G. Plewig (1999): Intederon gamma in survivors of the Chernobyl power plant accident: new therapeutic option for radiation-induced fibrosis. Int. J. Radiat. Oncol. Biol. Phys. 45, 147-152.
44. Pierce, G.F., J.E. Tarpley, J. Tseng, J. Bready, D. Chang, W.C. Kenney, R. Rudolph, M.C. Robson, J. Vande Berg, P. Reid, S. Kaufman & C.L. Farrell (1995): Detection of platelet-derived growth factor (PDGF)-AA in actively healing wounds treated with recombinant PDGF-BB and absence of PDGF in chronic nonhealing wounds. J. Clin. Invest. 96, 1336-1350.
45. Porock, D. & L. Kristjanson (1999): Skin reactions during radiotherapy for breast cancer: the use and impact of topical agents and dressings. Eur. J. Cancer Care (Engl) 8, 143-153.
46. Presto, S., A. Wehmeyer, A. Filbry, F. Rippke, S. Bielfeldt & J. Gaßmüller (1999): Hautregeneration durch medizinische Pflegepräparate mit 3% Dexpanthenol. Nachweis am human Saugblasen Modell. Dtsch. Dermatologe 47, 946-949.
47. Raber-Durlacher, J.E. (1999): Current practises for management of oral mucositis in cancer patients. Support Care Cancer 7, 71-74.
48. Ratliff, C. (1990): Impaired skin integrity related to radiation therapy. J. Enterostomal. Ther. 17, 193-198.
49. Rezvani, M., G.A. Ross, J.H. Wilkinson & A. Bywaters (2002): Evidence for humoral effects on the radiation response of rat foot skin. Br. J. Radiol. 75, 50-55.
50. Roy, I., A. Fortin & M. Larochelle (2001): The impact of skin washing with water and soap during breast irradiation: a randomized study, Radiother. Oncol. 58, 333-339.
51. Scherer, E. & H. Sack (1996): Strahlentherapie. Radiologische Onkologie. Springer-Verlag, Berlin, Heidelberg, New York.
52. Schmidt, F.W. (1999): Strahlentherapie: was Patienten wissen sollten. KF Haug Verlag, Heidelberg.
53. Schmuth, M., A. Sztankay, G. Weinlich, D.M. Linder, M.A. Wimmer, P.O. Fritsch & E. Fritsch (2001): Permeability barrier function of skin exposed to ionizing radiation. Arch. Dermatol. 137, 1019-1023.
54. Schratter-Sehn, A.U., K. Brinda, M. Kahrer & M. Novak (2001): Improvement of skin care during radiotherapy. Onkologie 24, 44-46.
55. Schreck, U., R. Schmidt, T. Sautter-Strelzyk, W. Budach & M. Bamberg (2000): Pflegerische Maßnahmen in der Radioonkologie. Onkologe 6, 516-528.
56. See, A., S. Wright & J.W. Denham (1998): A pilot study of dermofilm in acute radiation-induced desquamative skin reactions. Clin Oncol. (R. Coll. Radiol.) 10, 182-185.
57. Seegenschmiedt, M.H. (1998): Nebenwirkungen in der Onkologie - Internationale Systematik und Dokumentation. Springer-Verlag, Berlin, Heidelberg, New York.
58. Sitton, E. (1992): Early and late radiation-induced skin alterations. Part II: Nursing care of irradiated skin. Oncol. Nurs. Forum 19, 907-912.
59. Slyshenkov, V.S., M. Rakowska, A.G. Moiseenok & L. Wojtczak (1995): Panthothenic acid and its derivates protect Ehrlich ascites tumor cells against lipid peroxidation. Free Radic. Biol. Med. 19, 767-772.
60. Slyshenkov, V.S., S.N. Omelyanchik, A.G. Moiseenok, R.V. Trebukhina & L. Wojtczak (1998): Panthothenol protects rats against some deleterious effects of gamma radiation. Free Radic. Biol. Med. 24, 894-899.
61. Slyshenkov, V.S., S.N. Omelyanchik, A.G. Moiseenok, N.E. Petushok & L. Wojtczack (1999): Protection by panthothenol and beta-carotene againts liver damage produced by low-gamma radiation. Acta Biochim. Pol. 46, 239-248.
62. Smiell, J.M., J. Wieman, D.L. Steed, B.H. Perry, A.R. Sampson & B.H. Schwab (1999): Efficacy and safety of becaplermin (recombinant human platelet-derived growth factor-BB) in patients with nonhealing, lower extremity diabetic ulcers: a combined analysis of four randomized studies. Wound Rep. Reg. 7, 335-346.
63. Steinert, M., P. Gottlöber, H. Gall & R.U. Peter (2001): Subkutane Kalzifizierungen nach Strahlentherapie. Hautarzt 52, 518-521.
64. Szumacher, E., A. Wighton, E. Franssen, E. Chow, M. Tsao, I. Ackerman. L. Andersson, J. Kim, A. Wojcicka, Y. Ung, K. Sixel & C. Hayter (2001): Phase II study assessing the effectiveness of Bifine cream as prophylactic agent for ration-induced acute skin toxocity to the breast in women undergoing radiotherapy with concomitant CMF chemotherapy. Int. J. Radiol Oncol. Biol. Phys. 51, 81-86.
65. Thomas, R. & B. Stea (2002): Radiation recall dermatitis from high-dose interferon alfa-2b. J. Clin. Oncol. 20, 355-357.
66. Vogt, H.-J. (1998): Hauttumoren - Behandlung nach Strahlentherapie. Hautnah Schweiz 4/1998, 142-148.
67. Westbury, C., F. Hines, E. Hawkes, S. Ashley & M. Brada (2000): Advice on hair and scalp care during cranial radiotherapy: a prospective randomized trial. Radiother. Oncol. 54, 109-116.
68. Wijers, O.B., P.C. Levendag, E.R. Harms, A.M. Gan-Teng, P.I. Schmitz, W.D. Hendriks, E.B. Wilims, H. van der Est & L.L. Visch (2001): Mucositis reduction by selective elimination of oral flora in irradiated cancers of the head and neck: a Plazebo-controlled double-blind randomized study. Int. J. Radiat. Oncol. Biol. Phys. 50, 343-352.
69. Zimmermann, J.S., W. Budach & W. Dörr (1998): Individual skin care during radiation therapy. Strahlenther. Onkol. 174 [Suppl 3], 74-77.