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Volumn 132, Issue 3, 2002, Pages 441-449

Transforming growth factor-β1 induces hepatocyte apoptosis by a c-Jun independent mechanism

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0036747092     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(02)00109-5     Document Type: Article
Times cited : (9)

References (50)
  • 1
    • 0022297755 scopus 로고
    • Inhibitory effect of transforming growth factor-β on DNA synthesis of adult rat hepatocytes in primary culture
    • Nakamura T, Tomita Y, Hirai R, Yamaoka K, Kaji K, Ichihara A. Inhibitory effect of transforming growth factor-β on DNA synthesis of adult rat hepatocytes in primary culture. Biochem Biophys Res Commun 1985;133:1042-50.
    • (1985) Biochem Biophys Res Commun , vol.133 , pp. 1042-1050
    • Nakamura, T.1    Tomita, Y.2    Hirai, R.3    Yamaoka, K.4    Kaji, K.5    Ichihara, A.6
  • 2
    • 0023190821 scopus 로고
    • Transforming growth factor β inhibits DNA synthesis in heptocytes isolated from normal and regenerating rat liver
    • Strain AJ, Frazer A, Hill DJ, Milner RDG. Transforming growth factor β inhibits DNA synthesis in heptocytes isolated from normal and regenerating rat liver. Biochem Biophys Res Commun 1987;145:436-42.
    • (1987) Biochem Biophys Res Commun , vol.145 , pp. 436-442
    • Strain, A.J.1    Frazer, A.2    Hill, D.J.3    Milner, R.D.G.4
  • 3
    • 0024040124 scopus 로고
    • Type β transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat
    • Russell W, Coffey R, Ouellette A, Moses H. Type β transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. Proc Natl Acad Sci U S A 1988;85:5126-30.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 5126-5130
    • Russell, W.1    Coffey, R.2    Ouellette, A.3    Moses, H.4
  • 4
    • 0025326725 scopus 로고
    • Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation
    • Laiho M, DeCaprio JA, Ludow JW, Livingston DM, Massague J. Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation. Cell 1990;62:175-85.
    • (1990) Cell , vol.62 , pp. 175-185
    • Laiho, M.1    DeCaprio, J.A.2    Ludow, J.W.3    Livingston, D.M.4    Massague, J.5
  • 5
    • 0029883399 scopus 로고    scopus 로고
    • The retinoblastoma gene product inhibits TGF-beta1 induced apoptosis in primary rat hepatocytes and human HuH-7 hepatoma cells
    • Fan G, Ma X, Kren BT, Steer CJ. The retinoblastoma gene product inhibits TGF-beta1 induced apoptosis in primary rat hepatocytes and human HuH-7 hepatoma cells. Oncogene 1996;12:1909-19.
    • (1996) Oncogene , vol.12 , pp. 1909-1919
    • Fan, G.1    Ma, X.2    Kren, B.T.3    Steer, C.J.4
  • 7
    • 0028999861 scopus 로고
    • Transforming growth factor β1 preferentially induces apoptotic cell death in rat hepatocytes cultured under pericentral-equivalent conditions
    • Ohno K, Ammann P, Fasciati R, Maier P. Transforming growth factor β1 preferentially induces apoptotic cell death in rat hepatocytes cultured under pericentral-equivalent conditions. Toxicol Appl Pharmacol 1995;132:227-36.
    • (1995) Toxicol Appl Pharmacol , vol.132 , pp. 227-236
    • Ohno, K.1    Ammann, P.2    Fasciati, R.3    Maier, P.4
  • 8
    • 0030067146 scopus 로고    scopus 로고
    • The antiandrogen cyproterone acetate induces synthesis of transforming growth factor β1 in the parenchymal cells of the liver accompanied by an enhanced sensitivity to undergo apoptosis necrosis without inflammation
    • Oberhammer F, Nagy P, Tiefenbacher R, Froschl G, Bouzahzah B, Thorgeirsson S, et al. The antiandrogen cyproterone acetate induces synthesis of transforming growth factor β1 in the parenchymal cells of the liver accompanied by an enhanced sensitivity to undergo apoptosis and necrosis without inflammation. Hepatology 1996;23:329-37.
    • (1996) Hepatology , vol.23 , pp. 329-337
    • Oberhammer, F.1    Nagy, P.2    Tiefenbacher, R.3    Froschl, G.4    Bouzahzah, B.5    Thorgeirsson, S.6
  • 9
    • 0028953768 scopus 로고
    • Hepatic expression of mature transforming growth factor β1 in transgenic mice results in multiple tissue lesions
    • Sanderson N, Factor V, Nagy P, Kopp J, Kondaiah P, Wakefield L, et al. Hepatic expression of mature transforming growth factor β1 in transgenic mice results in multiple tissue lesions. Proc Natl Acad Sci U S A 1995;92:2572-6.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 2572-2576
    • Sanderson, N.1    Factor, V.2    Nagy, P.3    Kopp, J.4    Kondaiah, P.5    Wakefield, L.6
  • 12
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signalling from cell membrane to nucleus through SMAD proteins
    • Heldin CH, Miyazono K, Dijke PT. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 1997;390:465-71.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Dijke, P.T.3
  • 13
    • 0031035582 scopus 로고    scopus 로고
    • Evidence for a role of rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor β-mediated signaling
    • Atfi A, Djelloul S, Chastre E, Davis R, Gespach C. Evidence for a role of rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor β-mediated signaling. J Biol Chem 1997;272:1429-32.
    • (1997) J Biol Chem , vol.272 , pp. 1429-1432
    • Atfi, A.1    Djelloul, S.2    Chastre, E.3    Davis, R.4    Gespach, C.5
  • 14
    • 0030868250 scopus 로고    scopus 로고
    • Induction of apoptosis by DPC4, a transcriptional factor regulated by transforming growth factor-β through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) signaling pathway
    • Atfi A, Buisine M, Mazars A, Gespach C. Induction of apoptosis by DPC4, a transcriptional factor regulated by transforming growth factor-β through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) signaling pathway. J Biol Chem 1997;272:24731-4.
    • (1997) J Biol Chem , vol.272 , pp. 24731-24734
    • Atfi, A.1    Buisine, M.2    Mazars, A.3    Gespach, C.4
  • 15
    • 0025218491 scopus 로고
    • Autoinduction of transforming growth factor β1 is mediated by the AP-1 complex
    • Kim SJ, Angel P, Lafyatis R, Hattori K, Kim KY, Sporn MB, et al. Autoinduction of transforming growth factor β1 is mediated by the AP-1 complex. Mol Cell Biol 1990;10:1492-7.
    • (1990) Mol Cell Biol , vol.10 , pp. 1492-1497
    • Kim, S.J.1    Angel, P.2    Lafyatis, R.3    Hattori, K.4    Kim, K.Y.5    Sporn, M.B.6
  • 16
    • 0032512847 scopus 로고    scopus 로고
    • Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells
    • Guo YL, Baysal K, Kang B, Yang LJ, Williamson J. Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. J Biol Chem 1998;273:4027-34.
    • (1998) J Biol Chem , vol.273 , pp. 4027-4034
    • Guo, Y.L.1    Baysal, K.2    Kang, B.3    Yang, L.J.4    Williamson, J.5
  • 17
    • 0030998713 scopus 로고    scopus 로고
    • Induction of apoptosis by the transcription factor c-Jun
    • Bossy-Wetzel E, Bakiri L, Yaniv M. Induction of apoptosis by the transcription factor c-Jun. EMBO J 1997;6:1695-709.
    • (1997) EMBO J , vol.6 , pp. 1695-1709
    • Bossy-Wetzel, E.1    Bakiri, L.2    Yaniv, M.3
  • 18
    • 0030041536 scopus 로고    scopus 로고
    • Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in γ radiation-induced apoptosis
    • Chen YR, Meyer CF, Tan TH. Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in γ radiation-induced apoptosis. J Biol Chem 1996;271:631-4.
    • (1996) J Biol Chem , vol.271 , pp. 631-634
    • Chen, Y.R.1    Meyer, C.F.2    Tan, T.H.3
  • 19
    • 0029753773 scopus 로고    scopus 로고
    • The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation
    • Chen YR, Wang X, Templeton D, Davis RJ, Tan TH. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation. J Biol Chem 1996;271:31929-36.
    • (1996) J Biol Chem , vol.271 , pp. 31929-31936
    • Chen, Y.R.1    Wang, X.2    Templeton, D.3    Davis, R.J.4    Tan, T.H.5
  • 20
    • 0028846952 scopus 로고
    • Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells
    • Sawai H, Okazaki T, Yamamoto H, Okano H, Takeda Y, Tashima M, et al. Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells. J Biol Chem 1995;270:27326-31.
    • (1995) J Biol Chem , vol.270 , pp. 27326-27331
    • Sawai, H.1    Okazaki, T.2    Yamamoto, H.3    Okano, H.4    Takeda, Y.5    Tashima, M.6
  • 21
    • 0347537940 scopus 로고    scopus 로고
    • Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis
    • Verheij M, Bose R, Lin XH, Yao B, Jarvis WD, Grant S, et al. Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis. Nature 1996;380:75-9.
    • (1996) Nature , vol.380 , pp. 75-79
    • Verheij, M.1    Bose, R.2    Lin, X.H.3    Yao, B.4    Jarvis, W.D.5    Grant, S.6
  • 23
    • 0030780804 scopus 로고    scopus 로고
    • Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
    • Yang DD, Kuan CY, Whitmarsh AJ, Rincon M, Zheng TS, Davis RJ, et al. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 1997;389:865-70.
    • (1997) Nature , vol.389 , pp. 865-870
    • Yang, D.D.1    Kuan, C.Y.2    Whitmarsh, A.J.3    Rincon, M.4    Zheng, T.S.5    Davis, R.J.6
  • 25
    • 0031576388 scopus 로고    scopus 로고
    • c-Jun/AP-1 but not NF-κB, is a mediator for oxidant-initiated apoptosis in glomerular mesangial cells
    • Ishikawa Y, Yokoo T, Kitamura M. c-Jun/AP-1, but not NF-κB, is a mediator for oxidant-initiated apoptosis in glomerular mesangial cells. Biochem Biophys Res Commun 1997;240:496-501.
    • (1997) Biochem Biophys Res Commun , vol.240 , pp. 496-501
    • Ishikawa, Y.1    Yokoo, T.2    Kitamura, M.3
  • 26
    • 0030864876 scopus 로고    scopus 로고
    • Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism
    • Chauhan D, Pandy P, Ogata A, Teoh G, Treon S, Urashima M, et al. Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism. Oncogene 1997;15:837-43.
    • (1997) Oncogene , vol.15 , pp. 837-843
    • Chauhan, D.1    Pandy, P.2    Ogata, A.3    Teoh, G.4    Treon, S.5    Urashima, M.6
  • 27
    • 0031566152 scopus 로고    scopus 로고
    • Rapamycin potentiates dexamethasone-induced apoptosis and inhibits JNK activity in lymphoblastoid cells
    • Ishizuka T, Sakata N, Johnson G, Gelfland E, Terada N. Rapamycin potentiates dexamethasone-induced apoptosis and inhibits JNK activity in lymphoblastoid cells. Biochem Biophys Res Commun 1997;230:386-91.
    • (1997) Biochem Biophys Res Commun , vol.230 , pp. 386-391
    • Ishizuka, T.1    Sakata, N.2    Johnson, G.3    Gelfland, E.4    Terada, N.5
  • 29
    • 0031013545 scopus 로고    scopus 로고
    • Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway
    • Natoli G, Costanzo A, Ianni A, Templeton DJ, Woodgett JR, Balsano C, et al. Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway. Science 1997;275:200-3.
    • (1997) Science , vol.275 , pp. 200-203
    • Natoli, G.1    Costanzo, A.2    Ianni, A.3    Templeton, D.J.4    Woodgett, J.R.5    Balsano, C.6
  • 31
    • 0031282397 scopus 로고    scopus 로고
    • A role for JNK/SAPK in proliferation, but not apoptosis, of IL-3-dependent cells
    • Smith A, Ramos-Morales F, Ashworth A, Collins M. A role for JNK/SAPK in proliferation, but not apoptosis, of IL-3-dependent cells. Curr Biol 1997;7:893-6.
    • (1997) Curr Biol , vol.7 , pp. 893-896
    • Smith, A.1    Ramos-Morales, F.2    Ashworth, A.3    Collins, M.4
  • 32
    • 0030068097 scopus 로고    scopus 로고
    • Transfer of granulocyte-macrophage colon-stimulating factor gene to rat lung induces eosinophilia
    • Xing Z, Ohkawara Y, Jordana M, Graham F, Gauldie J. Transfer of granulocyte-macrophage colon-stimulating factor gene to rat lung induces eosinophilia. J Clin Invest 1996;97:1102-10.
    • (1996) J Clin Invest , vol.97 , pp. 1102-1110
    • Xing, Z.1    Ohkawara, Y.2    Jordana, M.3    Graham, F.4    Gauldie, J.5
  • 33
    • 0014330677 scopus 로고
    • The polypeptides of adenovirus. II. Soluble proteins, top components and the structure of the virion
    • Maizel J, White D, Scharff M. The polypeptides of adenovirus. II. Soluble proteins, top components and the structure of the virion. Virology 1968;36:126-36.
    • (1968) Virology , vol.36 , pp. 126-136
    • Maizel, J.1    White, D.2    Scharff, M.3
  • 34
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol 1976;13:29-83.
    • (1976) Methods Cell Biol , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 35
    • 0024556820 scopus 로고
    • Regulatory elements in the 5′-flanking region and the first intron contribute to transcriptional control of the mouse alpha 1 type I collagen gene
    • Rippe RA, Lorenzen SI, Brenner DA, Breindl M. Regulatory elements in the 5′-flanking region and the first intron contribute to transcriptional control of the mouse alpha 1 type I collagen gene. Mol Cell Biol 1989;9:2224-7.
    • (1989) Mol Cell Biol , vol.9 , pp. 2224-2227
    • Rippe, R.A.1    Lorenzen, S.I.2    Brenner, D.A.3    Breindl, M.4
  • 37
  • 38
    • 0029097265 scopus 로고
    • Sp1 binding activity increases in activated Ito cells
    • Rippe R, Almounajed G, Brenner D. Sp1 binding activity increases in activated Ito cells. Hepatology 1995;22:241-51.
    • (1995) Hepatology , vol.22 , pp. 241-251
    • Rippe, R.1    Almounajed, G.2    Brenner, D.3
  • 39
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in soluble extract from isolated mammalian nuclei
    • Dignam J, Lebovitz R, Roeder R. Accurate transcription initiation by RNA polymerase II in soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983;11:1475-89.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.1    Lebovitz, R.2    Roeder, R.3
  • 40
    • 0029872210 scopus 로고    scopus 로고
    • Apoptosis induced by transforming growth factor-β in fetal hepatocyte primary cultures
    • Sanchez A, Alvarez AM, Benito M, Fabregat I. Apoptosis induced by transforming growth factor-β in fetal hepatocyte primary cultures. J Biol Chem 1996;271:7416-22.
    • (1996) J Biol Chem , vol.271 , pp. 7416-7422
    • Sanchez, A.1    Alvarez, A.M.2    Benito, M.3    Fabregat, I.4
  • 41
    • 0029583937 scopus 로고
    • Role of transforming growth factor β1 on hepatic regeneration apoptosis in liver diseases
    • Takiya S, Tagaya T, Takahashi K, Kawashima H, Kamiya M, Fukuzawa Y, et al. Role of transforming growth factor β1 on hepatic regeneration and apoptosis in liver diseases. J Clin Pathol 1995;48:1093-7.
    • (1995) J Clin Pathol , vol.48 , pp. 1093-1097
    • Takiya, S.1    Tagaya, T.2    Takahashi, K.3    Kawashima, H.4    Kamiya, M.5    Fukuzawa, Y.6
  • 42
    • 0029897379 scopus 로고    scopus 로고
    • The recombinant proregion of transforming growth factor β1 (latency-associated peptide) inhibits active transforming growth factor β1 in transgenic mice
    • Bottinger EP, Factor VM, Tsang ML-S, Weatherbee JA, Kopp JB, Qian SW, et al. The recombinant proregion of transforming growth factor β1 (latency-associated peptide) inhibits active transforming growth factor β1 in transgenic mice. Proc Natl Acad Sci U S A 1996;93:5877-82.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5877-5882
    • Bottinger, E.P.1    Factor, V.M.2    Tsang, M.L.-S.3    Weatherbee, J.A.4    Kopp, J.B.5    Qian, S.W.6
  • 43
    • 0024515459 scopus 로고
    • Enhanced jun gene expression is an early genomic response to transforming growth factor-β stimulation
    • Pertovaara L, Sistonen L, Bos TJ, Vogt PK, Keski-Oja J, Alitalo K. Enhanced jun gene expression is an early genomic response to transforming growth factor-β stimulation. Mol Cell Biol 1989;9:1255-62.
    • (1989) Mol Cell Biol , vol.9 , pp. 1255-1262
    • Pertovaara, L.1    Sistonen, L.2    Bos, T.J.3    Vogt, P.K.4    Keski-Oja, J.5    Alitalo, K.6
  • 44
    • 0026595538 scopus 로고
    • Evidence for the involvement of protein kinase activity in transforming growth factor-β signal transduction
    • Ohtsuki M, Massague J. Evidence for the involvement of protein kinase activity in transforming growth factor-β signal transduction. Mol Cell Biol 1992;12:261-5.
    • (1992) Mol Cell Biol , vol.12 , pp. 261-265
    • Ohtsuki, M.1    Massague, J.2
  • 45
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell proliferation transformation
    • Angel P, Karin M. The role of Jun, Fos and the AP-1 complex in cell proliferation and transformation. Biochim Biophys Acta 1991;1072:129-57.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 46
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
    • Liu ZG, Hsu H, Goeddel DV, Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 1996;87:565-76.
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 47
    • 0028937610 scopus 로고
    • mapk in proliferating cultures of epithelial cells
    • mapk in proliferating cultures of epithelial cells. J Biol Chem 1995;270:7117-24.
    • (1995) J Biol Chem , vol.270 , pp. 7117-7124
    • Hartsough, M.T.1    Mulder, K.M.2
  • 48
    • 0030198199 scopus 로고    scopus 로고
    • TGF-β1 inhibits NF-κB/Rel activity inducing apoptosis of B cells: Transcriptional activation of IκBα
    • Arsura M, Wu M, Sonenshein GE. TGF-β1 inhibits NF-κB/Rel activity inducing apoptosis of B cells: transcriptional activation of IκBα. Immunity 1996;5:31-40.
    • (1996) Immunity , vol.5 , pp. 31-40
    • Arsura, M.1    Wu, M.2    Sonenshein, G.E.3
  • 49
    • 0030613532 scopus 로고    scopus 로고
    • Nuclear factor-κB/Rel blocks transforming growth factor β1-induced apoptosis of murine hepatocyte cell lines
    • Arsura M, FitzGerald MJ, Fausto N, Sonenshein GE. Nuclear factor-κB/Rel blocks transforming growth factor β1-induced apoptosis of murine hepatocyte cell lines. Cell Growth Differ 1997;8:1049-59.
    • (1997) Cell Growth Differ , vol.8 , pp. 1049-1059
    • Arsura, M.1    FitzGerald, M.J.2    Fausto, N.3    Sonenshein, G.E.4
  • 50
    • 0032696730 scopus 로고    scopus 로고
    • The transforming growth factor β(1)-inducible transcription factor TIEG1, mediates apoptosis through oxidative stress
    • Ribeiro A, Bronk SF, Roberts PJ, Urrutia R, Gores GJ. The transforming growth factor β(1)-inducible transcription factor TIEG1, mediates apoptosis through oxidative stress. Hepatology 1999;30:1490-7.
    • (1999) Hepatology , vol.30 , pp. 1490-1497
    • Ribeiro, A.1    Bronk, S.F.2    Roberts, P.J.3    Urrutia, R.4    Gores, G.J.5


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