Decreased cerebral blood flow in renal transplant recipients

Internal Medicine

Volumn 41, Issue 9, 2002, Pages 677-683

  Kamano, Chisako ^a   Komaba, Yuichi ^a   Sakayori, Osamu ^a   Ino, Yasuhiko ^a   Katayama, Yasuo ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Calcium; Cyclosporine; Deformability; Endothelin; SPECT (single photon emission computed tomography

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIHYPERTENSIVE AGENT; AZATHIOPRINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CREATININE; CYCLOSPORIN A; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IOFETAMINE I 123; METHYLPREDNISOLONE; MIZORIBINE; PREDNISOLONE;

ADULT; ARTICLE; ATHEROSCLEROSIS; BLOOD FLOW VELOCITY; BONE ATROPHY; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN ISCHEMIA; BRAIN REGION; CALCIFICATION; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DRUG BLOOD LEVEL; FEMALE; GRAFT REJECTION; HEMODIALYSIS; HUMAN; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; MALE; MEDICAL ASSESSMENT; NEUROTOXICITY; RECIPIENT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THALAMUS; WHITE MATTER;

EID: 0036746563     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.41.677     Document Type: Article

References (45)

1. Hohage H, Arlt M, Bruckner D, Dietl KH, Zidek W, Spieker C. Effects of cyclosporin A and FK 506 on lipid metabolism and fibrinogen in kidney transplant recipients. Clinical Transplantation 11: 225-230, 1997.
2. Vorstrup S, Lass P, Waldemar G, et al. Increased cerebral blood flow in anemic patients on long-term hemodialytic treatment. J Cereb Blood Flow Metab 12: 745-749, 1992.
3. Gottlieb D, Mildworf B, Rubinger D, Melamed E. The regional cerebral blood flow in patients under chronic hemodialytic treatment. J Cereb Blood Flow 7: 659-661, 1987.
4. Johnson WJ, McCarthy JT, Yanagihara T, et al. Effects of recombinant human erythropoietin on cerebral and cutaneous blood flow and on blood coagulability. Kidney Int 38: 919-924,1990.
5. Metry G, Wikström B, Valind S, et al. Effect of normalization of hematocrit on brain circulation and metabolism in hemodialysis patients. J Am Soc Nephrol 10: 854-863, 1999.
6. Driessen GK, Haest CW, Heidtmann H, Kamp D, Schmid-Schonbein H. Effect of reduced red cell "deformability" on flow velocity in capillaries of rat mesentery. Pflugers Arch 388: 75-78, 1980.
7. Iida H, Itoh H, Nakazawa M, et al. Quantitative mapping of regional cerebral bl ood flow using Iodine-123-IMP and SPECT. J Nucl Med 35: 2019-2030,1994.
8. Komaba Y, Nomoto T, Kitamura S, Terashi A. Cavernous angioma with olivary hypertrophy and contralateral cerebellar diaschisis. Intern Med 36: 504-507,1997.
9. Komaba Y, Kitamura S, Terashi A. Effect of prostaglandin E, on cerebral blood flow in patients with chronic cerebral infarction. Intern Med 37: 841-846, 1998.
10. Komaba Y, Osono E, Kitamura S, Katayama Y. Crossed cerebellocerebral diaschisis in patients with cerebellar stroke. Acta Neurol Scand 101: 8-12, 2000.
11. Kanai H, Hirakata H, Nakane H, et al. Depressed cerebral oxygen metabolism in patients with chronic renal failure: a positron emission tomography study. Am J Kidney Dis 38: S129-133, 2001.
12. Strandgaard S, Jones JV, MacKenzie ET, Harper AM. Upper limit of cerebral blood flow autoregulation in experimental renovascular hypertension in the baboon. Circ Res 37: 164-167, 1975.
13. Strandgaard S. Autoregulation of cerebral blood flow in hypertensive patients. The modifying influence of prolonged antihypertensive treatment on the tolerance to acute, drug-induced hypotension. Circulation 53: 720-727, 1976.
14. Barry DI, Strandgaard S, Graham DI, et al. Cerebral blood flow in rats with renal and spontaneous hypertension: resetting of the lower limit of autoregulation. J Cereb Blood Flow Metab 2: 347-353, 1982.
15. Harper SL, Bohlen HG. Microvascular adaptation in the cerebral cortex of adult spontaneously hypertensive rats. Hypertension 6: 408-419, 1984.
16. Vorstrup S, Barry DI, Jarden JO, et al. Chronic antihypertensive treatment in the rat reverses hypertension-induced changes in cerebral blood flow autoregulation. Stroke 15: 312-318, 1984.
17. Muller F, Lartaud I, Bray L, et al. Chronic treatment with the angiotensin I converting enzyme inhibitor, perindopril, restores the lower limit of autoregulation of cerebral blood flow in the awake renovascular hypertensive rat. J Hypertens 8: 1037-1042, 1990.
18. Christians U, Sewing KF. Cyclosporin metabolism in transplant patients. Pharmac Ther 57: 291-345, 1993.
19. Cohen DJ, Loertscher R, Rubin ME, Tilney NL, Carpenter CB, Strom TB. Cyclosporine: a new immunosuppressive agent for organ transplantation. Ann Intern Med 101: 667-682, 1984.
20. Khalil A, Carrier M, Latour JG, Pelletier LC. Cyclosporine A decreases coronary blood flow in dogs. Ann Chir 49: 689-693, 1995.
21. Andreoni KA, O'Donnell CP, Burdick JF, Robotham JL. Hepatic and renal blood flow responses to a clinical dose of intravenous cyclosporine in the pig. Immunopharmacology 28: 87-94, 1994.
22. Sandberg JO, Groth CG, Andersson A, Jansson L. Acute effects of different immunosuppressive drugs on pancreatic, islet, renal, and arterial hepatic blood flow in anesthetized rats. Transpl Int 7: 319-323, 1994.
23. Baskurt OK, Senturk UK, Dayan N, et al. Cyclosporin A affects red blood cell deformability in vivo but not in vitro in guinea pig. J Pharmacol Exp Ther 274: 1438-1442, 1995.
24. 2+-dependent regulation of the spectrin/actin interaction by calmodulin and protein 4.1. J Biol Chem 266: 1134-1140, 1991.
25. Friederichs E, Meiselman HJ. Effects of calcium permeabilization on RBC rheologic behavior. Biorheology 31: 207-215, 1994.
26. Babarykin D, Amerika D, Adamsone I, Valinietse M, Rosental R. Effect of Sandimmun Neoral on the level of bivalent cations in erythrocytes of kidney transplant recipients. Ann Transplant 1: 23-26, 1996.
27. Schut NH, Bilo HJ, Popp-Snijders C, Goedhart PT, Wilmink JM. Erythrocyte deformability, endothelin levels, and renal function in cyclosporin-treated renal transplant recipients: effects of intervention with fish oil and corn oil. Scand J Clin Lab Invest 53: 499-506, 1993.
28. Auch-Schwelk W, Bossaller C, Götze S, Thelen J, Fleck E. Endothelial and vascular smooth muscle function after chronic treatment with cyclosporin A. J Cardiovasc Pharmacol 21: 435-440, 1993.
29. Bunchman TE, Brookshire CA. Cyclosporine-induced synthesis of endotheline by cultured human endothelial cells. J Clin Invest 88: 310-314, 1991.
30. Nakahama H. Stimulatory effect of cyclosporine A on endothelin secretion by a cultured renal epithelial cell line, LLC-PK1. Eur J Pharmacol 180: 191-192, 1990.
31. Nakahama H, Fukunaga M, Kakihara M, et al. Comparative effects of cyclosporine and FK-506 on endothelin secretion by a cultured renal cell line, LLC-PK1. J Cardiovasc Pharmacol 17 Suppl 7: S172-S173, 1991.
32. Kon V, Sugiura M, Inagami T, Harvie BR, Ichikawa I, Hoover RL. Role of endotherin in cyclosporine-induced glomerular dysfunction. Kidney Int 37: 1487-1491, 1990.
33. Grieff M, Loertscher R, Shohaib SA, Stewart DJ. Cyclosporine-induced elevation in circulating endothelin-1 in patients with solid-organ transplants. Transplantation 56: 880-884, 1993.
34. Nakayama Y, Nonoguchi H, Kiyama S, et al. Intranephron distribution and regulation of endothelin-converting enzyme-1 in cyclosporin A-induced acute renal failure in rats. J Am Soc Nephrol 10: 562-571, 1999.
35. Salom JB, Torregrosa G, Miranda FJ, Alabadí JA, Alvarez C, Alborch E. Effects of endothelin-1 on the cerebrovascular bed of the goat. Eur J Pharmacol 192: 39-45, 1991.
36. Gijtenbeek JM, van den Bent MJ, Vecht CJ. Cyclosporine neurotoxicity: a review. J Neurol 246: 339-346, 1999.
37. Hauss WH, Mey J, Schulte H. Effect of risk factors and antirheumatic drugs on the proliferation of aortic wall cells. Atherosclerosis 34: 119-143, 1979.
38. Lee WM, Morrison ES, Scott RF, Lee KT, Kroms M. Effects of methyl prednisolone and colchicine on the development of atherosclerosis in swine. Atherosclerosis 25: 213-224, 1976.
39. Kubota RT. Resnik CS. Periarticular calcification in immunosuppressed cardiac transplant patients. Invest Radiol 23: 113-117, 1988.
40. Richter-Reichhelm HB, Schulte AE. Results of a cyclosporin A ringstudy. Toxicology 128: 91-94, 1998.
41. Canavese C, Cesarani F, Stratta C, et al. Dramatic worsening of vascular calcifications after kidney transplantation in spite of early parathyroidectomy. Clin Nephrol 54: 487-491, 2000.
42. Hofbauer LC, Shui C, Riggs BL, et al. Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells. Biochem Biophys Res Commun 280: 334-339, 2001.
43. Lindner A, Charra B, Sherrard DJ, Scribner BH. Accelerated atherosclerosis in prolonged maintenance hemodialysis. N Engl J Med 28: 290: 697-701, 1974.
44. London GM, Drueke TB. Atherosclerosis and arteriosclerosis in chronic renal failure. Kidney Int 51: 1678-1695, 1997 (editorial).
45. Massy ZA, Chadefaux-Vekemans B, Chevalier A, et al. Hyperhomocysteinaemia: a significant risk factor for cardiovascular disease in renal transplant recipients. Nephrol Dial Transplant 9: 1103-8, 1994.