Use of antifungal agents in febrile patients nonresponsive to antibacterial treatment: The current status in surgical and critical care patients in Japan

Journal of Infection and Chemotherapy

Volumn 8, Issue 3, 2002, Pages 237-241

  Aikawa, Naoki ^a   Sumiyama, Yoshinobu ^b   Kusachi, Shinya ^b   Hirasawa, Hiroyuki ^c   Oda, Shigeto ^c   Yamazaki, Yoji ^d  

^a KEIO UNIVERSITY HOSPITAL   (Japan)

^b TOHO UNIVERSITY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Antifungal agents; Candidiasis; Critical care; Multicenter study; Surgical patients

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; FLUCONAZOLE; MICONAZOLE;

ADULT; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL THERAPY; ARTICLE; BLOOD CULTURE; BODY TEMPERATURE; CANDIDIASIS; CRITICAL ILLNESS; FEMALE; FEVER; FUNGUS ISOLATION; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE; JAPAN; MAJOR CLINICAL STUDY; MALE; SURGICAL PATIENT;

EID: 0036744649     PISSN: 1341321X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10156-002-0182-x     Document Type: Article

References (12)

1. Jarvis WR, Martone WJ. Predominant pathogens in hospital infections. J Antimicrob Chemother 1992;29 (Suppl A):19-24.
2. Beck-Sague CM, Jarvis WR. Secular trends in the epidemiology of nosocomial fungal infection in the United States,1980-1990. J Infect Dis 1993;167:1247-51.
3. Pittet D, Wenzel RP. Nosocomial bloodstream infections; secular trends in rates, mortality, and contribution to total hospital deaths. Arch Intern Med 1995;155:1177-85.
4. Rangel-Frausto MS, Wiblin T, Blumberg HM, Saiman L, Patterson J, Rinaldi M. et al. National Epidemiology of Mycoses Survey (NEMIS): variations in rates of bloodstream infections due to Candida species in seven surgical intensive care units and six neonatal intensive care units. Clin Infect Dis 1999;29:253-8.
5. Vincent JL, Bihari DJ, Suter PM, Bruining HA, White J, Nicolas-Chanoin MH. et al. The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) study. JAMA 1995;274:639-44.
6. Aikawa N, Tanimura S, Kawano S, Yoshida M. Diagnosis and treatment of systemic candida infection in non-neutropenic patients (in Japanese). Jpn J Antibiot 1998;51:721-34.
7. Pittet D, Monod M, Suter PM, Frenk E, Auckenthaler R. Candida colonization and subsequent infections in critically ill surgical patients. Ann Surg 1994;220:751-8.
8. Solomkin JS. Timing of treatment for nonneutropenic patients colonized with Candida. Am J Surg 1996;172 (Suppl 6A):44S-8S.
9. Dean DA, Burchard KW. Surgical perspective on invasive Candida infections. World J Surg 1998;22:127-34.
10. Nakao A, Yasui M, Kawagoe T, Tamura H, Tanaka S, Takagi H. False-positive endotoxemia derives from gauze glucan after hepatectomy for hepatocellular carcinoma with cirrhosis. Hepatogastroenterology 1997;44:1413-8.
11. Edward JE Jr. Candidemia and Candida catheter associated sepsis. In: Holmberg K, Mayer RO, editors. Diagnosis and therapy of systemic fungal infections. New York: Raven; 1989. p. 39-46.
12. Rex JH, Bennett JE, Sugar AM, Pappas PG, van der Horst CM, Edwards JE. et al. A randomized trial comparing fluconazole with amphotericin B for the treatment of candidemia in patients without neutropenia. N Engl J Med 1994;331:1325-30.