Foal with Overo lethal white syndrome born to a registered quarter horse mare;Poulain né d'une jument quarter horse enregistrée et présentant le syndrome létal de l'Ovéro blanc

Canadian Veterinary Journal

Volumn 43, Issue 9, 2002, Pages 715-717

  Lightbody, Tamara ^a  

^a Peterborough Veterinary Services   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; AUTOPSY; AUTOSOMAL DOMINANT DISORDER; CLINICAL EXAMINATION; COLIC; COLON AGANGLIONOSIS; DNA DETERMINATION; EUTHANASIA; HORSE; ILEUM DISEASE; LETHAL MUTANT; NEWBORN; NONHUMAN;

ANIMALS; ANIMALS, NEWBORN; COLON; FATAL OUTCOME; FEMALE; GENES, LETHAL; HAIR COLOR; HIRSCHSPRUNG DISEASE; HORSE DISEASES; HORSES; ILEUM; SYNDROME;

EQUUS CABALLUS;

EID: 0036744309     PISSN: 00085286     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. McCabe L, Griffin LD, Kinzer A, Chandler M, Beckwith JB, McCabe RB. Overo lethal white foal syndrome; equine model of aganglionic megacolon (Hirschsprung disease). Am J Med Genet 1990;36:336-340.
2. Vrotsos PD, Santschi EM, Purdy AK, Mickelson JR. Incidence of an endothelin receptor B mutation in white patterned horses; evidence for genetic heterogeneity in the overo coat pattern. Plant Anim Genome VII Conf, San Diego, California, 1999.
3. Bowling AT. Dominant inheritance of overo spotting in paint horses. J Hered 1994;85:222-225.
4. Yang GC, Croaker D, Zhang AL, Manflick P, Cartmill T, Cass D. A dinucleotide mutation in the endothelin-B receptor gene is associated with lethal white foal syndrome (LWFS); a horse variant of Hirschsprung disease. Human Mol Gene 1998;6:1047-52.
5. James RM, Santschi EM. Role of the endothelin receptor B gene in overo coat color pattern and lethal white foal syndrome. Plant Anim Genome VII Conf, San Diego, California, 1999.
6. Lane PW, Liu HM. Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered 1984;75:435-439.
7. Santschi EM, Purdy AK, Valberg SJ, Vrotsos PD, Kaese H, Mickelson JR. Endothelin receptor B polymorphism associated with lethal white foal syndrome in horses. Mamm Genome 1998; 4:306-309.