Mechanisms of inhibitory activity of the aldose reductase inhibitor, epalrestat, on high glucose-mediated endothelial injury: Neutrophil-endothelial cell adhesion and surface expression of endothelial adhesion molecules

Journal of Diabetes and its Complications

Volumn 16, Issue 5, 2002, Pages 321-326

  Okayama, Naotsuka ^a   Omi, Hitoshi ^a   Okouchi, Masahiro ^a   Imaeda, Kenro ^a   Kato, Takashi ^a   Akao, Masaya ^a   Imai, Seiji ^a   Shimizu, Manabu ^a   Fukutomi, Tatsuya ^a   Itoh, Makoto ^a  

^a NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

E selectin; Intercellular adhesion molecule 1; Nitric oxide; P selectin; Protein kinase C

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EPALRESTAT; GLUCOSE; INTERCELLULAR ADHESION MOLECULE 1; MYELOPEROXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PADGEM PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM INJURY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UMBILICAL VEIN;

ALDEHYDE REDUCTASE; CELL ADHESION; CELL ADHESION MOLECULES; CELLS, CULTURED; E-SELECTIN; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; KINETICS; NEUTROPHILS; P-SELECTIN; PEROXIDASE; RHODANINE; TETRADECANOYLPHORBOL ACETATE; THIAZOLIDINES; UMBILICAL VEINS;

EID: 0036740927     PISSN: 10568727     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8727(02)00178-2     Document Type: Article

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