Dry granulation with a roller compactor part II: Evaluating the operation modes

Pharmaceutical Technology Europe

Volumn 14, Issue 9, 2002, Pages 32-39

  Shlieout, George ^a   Lammens, Robert F ^a   Kleinebudde, Peter ^a   Bultmann, Martin ^a  

^a Solvay Pharmaceuticals GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LACTOSE; MICROCRYSTALLINE CELLULOSE;

ARTICLE; AUTOMATION; DRUG GRANULATION; DRUG INDUSTRY; DRUG MANUFACTURE; DRUG PACKAGING; DRUG QUALITY; DRY POWDER; EXPERIMENTATION; FORCE; MATERIALS HANDLING; PARAMETER; PHARMACEUTICAL ENGINEERING; PROCESS CONTROL; TABLET COMPRESSION; TABLET MACHINE; VELOCITY;

EID: 0036740629     PISSN: 01646826     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. G. Shlieout, R.F. Lammens and P. Kleinebudde, "Dry Granulation with a Roller Compactor Part I: The Functional Units and Operation Modes," Pharm. Technol. Eur. 12(11), 24-35 (2000).
2. S. Inghelbrecht, J.P. Remon and P. de Backer, "Instrumentation of a Roll Compactor and the Evaluation of the Parameter Setting by Neural Networks," Int. J. Pharm. 103-115 (1997).
3. S. Inghelbrecht and J.P. Remon, "The Roller Compaction of Different Types of Lactose," Int. J. Pharm. 166, 135-144 (1998).
4. A. Falzone, G.E. Peck and G.P. McCabe, "Effect of Changes in Roller Compactor Parameters on Granulations Produced by Compaction", Drug Dev. Ind. Pharm. 18, 469-489 (1992).
5. R.F. Lammens and C. Pörtner, "Control of Production Quality During Dry Granulation with Roll Compactors," Proceedings of the 3rd World Meeting APV/APGI (3-6 April 2000, Berlin, Germany).
6. J.M. Bultmann, "The Influence of Magnesium Stearate Addition on the Roller Compaction Process and Product Properties," proceedings of the 20th Pharmaceutical Technology Conference, (Liverpool, UK, 2001).
7. G. Shlieout et al., "Calibration of Force and Gap of Gerteis Roller Compactor and Methods to Determine Porosity and Micro Hardness of Ribbons," Pharm. Sci. 1, S-327 (1999).
8. R.F. Lammens, "Roll Compactor Instrumentation," Proceedings of the 4th World Meeting ADRITELF/APV/APGI (8-11 April 2002, Florence, Italy).