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Volumn 15, Issue 9, 2002, Pages 1158-1165

Neonicotinoid insecticides: Reduction and cleavage of imidacloprid nitroimine substituent by liver microsomal and cytosolic enzymes

(3) Schulz Jander, Daniel A a Leimkuehler, William M b Casida, John E a

a UNIVERSITY OF CALIFORNIA (United States)

b Bayer Research Park (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXY IMIDACLOPRID; ALDEHYDE REDUCTASE; ALRESTATIN; ARGON; CARBENOID; CARBOXYLIC ACID DERIVATIVE; CHLOROFORMIC ACID ETHYL ESTER; CYTOCHROME P450; ENZYME INHIBITOR; ETHYL 1 BENZYL 3 HYDROXY 2(5H) OXOPYRROLE 4 CARBOXYLATE; FUNCTIONAL GROUP; HYDRAZONE DERIVATIVE; IMIDACLOPRID; IMINE; INSECTICIDE; KETOCONAZOLE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NICOTINE DERIVATIVE; NITRO DERIVATIVE; NITROREDUCTASE; OXIDOREDUCTASE; PHENOBARBITAL; PONALRESTAT; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHINE OXIDASE;

ARTICLE; ATMOSPHERE; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; HUMAN; LIQUID CHROMATOGRAPHY; LIVER CYTOSOL; LIVER METABOLISM; LIVER MICROSOME; MASS SPECTROMETRY; METABOLITE; NONHUMAN; QUANTITATIVE ANALYSIS; RABBIT; RAT; REDUCTION;

ANIMALS; CHROMATOGRAPHY, THIN LAYER; CYTOCHROME P-450 ENZYME SYSTEM; CYTOSOL; ENZYME INHIBITORS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GUANIDINES; HUMANS; HYDRAZONES; IMIDAZOLES; IMINES; INSECTICIDES; KINETICS; MICROSOMES, LIVER; NAD(P)H DEHYDROGENASE (QUINONE); NADP; OXIDATION-REDUCTION; PLANTS; RABBITS; RECOMBINANT PROTEINS;

ORYCTOLAGUS CUNICULUS;

EID: 0036739990 PISSN: 0893228X EISSN: None Source Type: Journal
DOI: 10.1021/tx0200360 Document Type: Article

Times cited : (63)

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