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Volumn 16, Issue 9, 2002, Pages 1808-1817

Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro

(6) Akutsu, M a Furukawa, Y b Tsunoda, S a Izumi, T a,b Ohmine, K a,b Kano, Y a

a TOCHIGI CANCER CENTER (Japan)

b JICHI MEDICAL UNIVERSITY (Japan)

Author keywords

Antagonism; Cytarabine; Isobologram; Methotrexate; Synergism

Indexed keywords

CYTARABINE; METHOTREXATE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BURKITT LYMPHOMA; CELL CYCLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG CYTOTOXICITY; DRUG POTENTIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL LINE; MITOSIS INHIBITION; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; T CELL LEUKEMIA;

EID: 0036739780 PISSN: 08876924 EISSN: None Source Type: Journal
DOI: 10.1038/sj.leu.2402573 Document Type: Article

Times cited : (23)

References (48)

1
- 0024379544
- LNH-84 regimen: A multicenter study of intensive chemotherapy in 737 patients with aggressive malignant lymphoma
- (1989) J. Clin. Oncol , vol.7 , pp. 1018-1026
- Coiffier, B.¹ Gisselbrecht, C.² Herbrecht, R.³ Tilly, H.⁴ Bosly, A.⁵ Brousse, N.⁶

2
- 0028204905
- Treatment of childhood acute lymphoblastic leukemia: Results of Dana-Farber Cancer Institute/Children's Hospital Acute lymphoblastic leukemia Consortium Protocol 85-01
- (1994) J. Clin. Oncol , vol.12 , pp. 740-747
- Schorin, M.A.¹ Blattner, S.² Gelber, R.D.³ Tarbell, N.J.⁴ Donnelly, M.⁵ Dalton, V.⁶ Cohen, H.J.⁷ Sallan, S.E.⁸

3
- 0032941871
- Intraventricular concentration times time (C × T) methotrexate and cytarabine for patients with recurrent meningeal leukemia and lymphoma
- (1999) Cancer , vol.85 , pp. 511-516
- Moser, A.M.¹ Adamson, P.C.²

4
- 0025096376
- Prevention of meningeal leukemia. Review of 20 years of research and current recommendations
- (1990) Hematol. Oncol. Clin. N. Am , vol.4 , pp. 951-969
- Porchedly, C.¹

5
- 0028282876
- Prevention and treatment of meningeal leukemia in children
- (1994) Blood , vol.84 , pp. 355-366
- Pinkel, D.¹ Woo, S.²

6
- 0025958183
- Superiority of ProMACE-CytaBOM over ProMACEMOPP in the treatment of advanced diffuse aggressive lymphoma: Results of a prospective randomized trial
- (1991) J. Clin. Oncol , vol.9 , pp. 25-38
- Longo, D.L.¹ DeVita, V.T.² Duffey, P.L.³ Wesley, M.N.⁴ Ihde, D.C.⁵ Hubbard, S.M.⁶ Gilliom, M.⁷ Jaffe, E.S.⁸ Cossman, J.⁹ Fisher, R.I.¹⁰

7
- 0033570984
- A phase II trial of 200% Pro-MACE-CytaBOM in patients with previously untreated aggressive lymphomas: Analysis of response, toxicity, and dose intensity
- (1999) Blood , vol.94 , pp. 3307-3314
- Gordon, L.I.¹ Young, M.² Weller, E.³ Habermann, T.M.⁴ Winter, J.N.⁵ Glick, J.⁶ Ghosh, C.⁷ Flynn, P.⁸ Cassileth, P.A.⁹

8
- 0027457160
- AMOPLACE treatment of intermediate-grade and high-grade malignant lymphoma: A Cancer and Leukemia Group B study
- (1993) J. Clin. Oncol , vol.11 , pp. 248-254
- Parker, B.A.¹ Santarelli, M.² Green, M.R.³ Anderson, J.R.⁴ Cooper, M.R.⁵ Case, D.⁶ Barcos, M.⁷ Peterson, B.A.⁸ Gottlieb, A.J.⁹

9
- 0031904557
- Consolidation therapy with antimetabolite-based therapy in standard-risk acute lymphoblastic leukemia of childhood: A pediatric oncology group study
- (1998) J. Clin. Oncol , vol.16 , pp. 2840-2847
- Harris, M.B.¹ Shuster, J.J.² Jeanette Pullen, D.³ Borowitz, M.J.⁴ Carroll, A.J.⁵ Behm, F.G.⁶ Land, V.J.⁷

10
- 0035300618
- Value of high-dose cytarabine during interval therapy of a Berlin-Frankfurt-Munster-based protocol in increased-risk children with acute lymphoblastic leukemia and lymphoblastic lymphoma: Results of the European Organization for Research a
- (2001) J. Clin. Oncol , vol.19 , pp. 1935-1942
- Millot, F.¹ Suciu, S.² Philippe, N.³ Benoit, Y.⁴ Mazingue, F.⁵ Uyttebroeck, A.⁶ Lutz, P.⁷ Mechinaud, F.⁸ Robert, A.⁹ Boutard, P.¹⁰ Marguerite, G.¹¹ Ferster, A.¹² Plouvier, E.¹³ Rialland, X.¹⁴ Behard, C.¹⁵ Plantaz, D.¹⁶ Dresse, M.F.¹⁷ Philippet, P.¹⁸ Norton, L.¹⁹ Thyss, A.²⁰ Dastugue, N.²¹ Wat²² more..

11
- 0026067558
- High survival rate in advanced-stage B-cell lymphomas and leukemias without CNS involvement with a short intensive polychemotherapy: Results from the French Pediatric Oncology Society of a randomized trial of 216 children
- (1991) J. Clin. Oncol , vol.9 , pp. 123-132
- Patte, C.¹ Philip, T.² Rodary, C.³ Zucker, J.M.⁴ Behrendt, H.⁵ Gentet, J.C.⁶ Lamagnere, J.P.⁷ Otten, J.⁸ Dufillot, D.⁹ Pein, F.¹⁰

12
- 0029865739
- Primary non-Hodgkin's lymphoma of the CNS treated with BVAM or CHOD/BVAM chemotherapy before radiotherapy
- (1996) J. Clin. Oncol , vol.14 , pp. 945-954
- Bessell, E.M.¹ Graus, F.² Punt, J.A.³ Firth, J.L.⁴ Hope, D.T.⁵ Moloney, A.J.⁶ Lopez Guillermo, A.⁷ Villa, S.⁸

13
- 9244240250
- Improved survival for children with B-cell acute lymphoblastic leukemia and stage IV small noncleaved-cell lymphoma: A pediatric oncology group study
- (1996) J. Clin. Oncol , vol.14 , pp. 1252-1261
- Bowman, W.P.¹ Shuster, J.J.² Cook, B.³ Griffin, T.⁴ Behm, F.⁵ Pullen, J.⁶ Link, M.⁷ Head, D.⁸ Carroll, A.⁹ Berard, C.¹⁰ Murphy, S.T.I.¹¹

14
- 0033964380
- Results of treatment with Hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia
- (2000) J. Clin. Oncol , vol.18 , pp. 547-561
- Kantarjian, H.M.¹ O'Brien, S.² Smith, T.L.³ Cortes, J.⁴ Giles, F.J.⁵ Beran, M.⁶ Pierce, S.⁷ Huh, Y.⁸ Andreeff, M.⁹ Koller, C.¹⁰ Ha, C.S.¹¹ Keating, M.¹² Murphy, S.¹³ Freireich, E.J.¹⁴

15
- 0010421579
- Cytosine in combination with 6-mercaptopurine, methotrexate, or 5-fluorouracil in L1210 mouse leukemia
- (1967) Cancer Chemother. Rep , vol.51 , pp. 435-438
- Burchenal, J.H.¹ Dollinger, M.R.²

16
- 0015307531
- Interaction of drugs inhibiting different steps in the synthesis of DNA
- (1972) Cancer Res , vol.32 , pp. 527-531
- Grindey, G.¹ Nichol, C.A.²

17
- 0015596316
- Enhancement of the antiproliferative action of 1-b-D-arabinofuranosylcytosine by methotrexate in murine leukemia cells
- (L5178Y)
- (1973) Cancer Res , vol.33 , pp. 521-525
- Hoovis, M.L.¹ Chu, M.Y.²

18
- 0015603401
- Combination chemotherapy: The antagonism of methotrexate and cytosine arabinoside
- (1973) Eur. J. Cancer , vol.9 , pp. 229-232
- Tattersall, M.H.¹ Harrap, K.R.²

19
- 0016210244
- Dose-related synergism of cytosine arabinoside and methotrexate against murine leukemia L1210
- (1974) Eur. J. Cancer , vol.10 , pp. 425-429
- Avery, T.L.¹ Roberts, D.²

20
- 0016798342
- The enhanced cytotoxicity of combinations of 1-b-D-arabinofuranosylcytosine and methotrexate
- (1975) Cancer Res , vol.35 , pp. 1555-1558
- Edelson, M.¹ Vietti, T.² Valeriote, F.³

21
- 0018721428
- Mechanism of synergistic cell killing when methotrexate precedes cytarabine: Study of L1210 and human leukemia cells
- (1979) J. Clin. Invest , vol.64 , pp. 788-797
- Cadman, E.¹ Eiferman, F.²

22
- 0018633235
- Methotrexcate-induced changes in the levels of 1-b-D-arabinofuranosylcytosine triphosphate in L1210 cells
- (1979) Cancer Res , vol.39 , pp. 4048-4054
- Roberts, D.W.¹ Peck, C.² Hilliard, C.³ Wingo, W.⁴

23
- 0019377175
- Synergistic and antagonistic interactions of methotrexate and 1-b-D-arabinofuranosylcytosine in hepatoma cells: The modulating effect of purines
- (1981) Biochem. Pharmacol , vol.30 , pp. 223-229
- Jackson, R.C.¹ Harkrader, R.J.²

24
- 0024600654
- Synergistic effect of methotrexate and 1-beta-D-arabinofuranosylcytosine on the generation of DNA strand breaks in a human promyelocytic leukemia cell line
- (1989) Leuk. Res , vol.13 , pp. 151-156
- Tanizawa, A.¹ Kubota, M.² Takimoto, T.³ Kito, T.⁴ Akiyama, Y.⁵ Kiriyama, Y.⁶ Mikawa, H.⁷

25
- 0024847290
- What is synergy?
- (1988) Pharmacol. Rev , vol.41 , pp. 93-141
- Berenbaum, M.C.¹

26
- 0028609109
- Concepts of synergism and antagonism
- (1994) Anticancer Res , vol.14 , pp. 2315-2320
- Merlim, J.L.¹

27
- 0010462244
- Drug synergism in antineoplastic chemotherapy
- (1964) Adv. Chemother , vol.1 , pp. 397-498
- Vendette, J.M.¹ Goldin, A.²

28
- 0001663843
- The problem of synergism and antagonism of combined drugs
- (1953) Arzneim Forsch , vol.3 , pp. 285-290
- Loewe, S.¹

29
- 0001458215
- Effect of more than one inhibitor
- Academic Press: New York
- (1963) Enzymes and Metabolic Inhibitors , pp. 66-79
- Webb, J.L.¹

30
- 0028153260
- Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: A rational approach to clinical protocol design
- (1994) Nat. Cancer Inst , vol.86 , pp. 1517-1524
- Chou, T.C.¹ Motzer, R.J.² Tong, Y.³ Bosl, G.J.⁴

31
- 0018425119
- Exploitable mechanisms in combined radiotherapy-chemotherapy: The concept of additivity
- (1979) Int. J. Radiat. Oncol. Biol. Phys , vol.5 , pp. 8-91
- Steel, G.G.¹ Peckham, M.J.²

32
- 0017378227
- Establishment of an Epstein-Barr virus-determined nuclear antigen-negative human B-cell line from acute lymphoblastic leukemia
- (1977) J. Natl. Cancer Inst , vol.59 , pp. 93-94
- Hiraki, S.¹ Miyoshi, I.² Masuji, H.³ Kubonishi, I.⁴ Matsuda, Y.⁵

33
- 0026409196
- In vitro effects of amsacrine in combination with other anticancer agents
- (1991) Leukemia Res , vol.15 , pp. 1059-1064
- Kano, Y.¹ Sakamoto, S.² Kasahara, T.³ Akutsu, M.⁴ Inoue, Y.⁵ Miura, Y.⁶

34
- 0023873482
- Effects of vincristine in combination with methotrexate and other antitumor agents in human acute lymphoblastic leukemia cells in culture
- (1988) Cancer Res , vol.48 , pp. 351-356
- Kano, Y.¹ Ohnuma, T.² Okano, T.³ Holland, J.F.⁴

35
- 0026587170
- Effects of CPT-11 in combination with other anticancer agents in culture
- (1992) Int. J. Cancer , vol.50 , pp. 604-609
- Kano, Y.¹ Suzuki, K.² Akutsu, M.³ Suda, K.⁴ Inoue, Y.⁵ Yoshida, M.⁶ Sakamoto, S.⁷ Miura, Y.⁸

36
- 0031832323
- In vitro schedule-dependent interaction between paclitaxel and SN-38 (the active metabolite of irinotecan) in human carcinoma cell lines
- (1998) Cancer Chemother. Pharmacol , vol.42 , pp. 91-98
- Kano, Y.¹ Akutsu, M.² Tsunoda, S.³ Suzuki, K.⁴ Adachi, K.⁵

37
- 0034647528
- Phosphorylation of bcl-2 protein by cdc2 kinase during G2/M phases and its role in cell cycle regulation
- (2000) J. Biol. Chem , vol.275 , pp. 21661-21667
- Furukawa, Y.¹ Iwase, S.² Kikuchi, J.³ Nakamura, M.⁴ Terui, Y.⁵ Yamada, H.⁶ Kano, Y.⁷ Matsuda, M.⁸

38
- 0025097850
- Increase in topoisomerase-II-mediated DNA breaks and cytotoxicity of VP16 in human U937 lymphoma cells pretreated with low doses of methotrexate
- (1990) Int. J. Cancer , vol.45 , pp. 156-162
- Lorico, A.¹ Boiocchi, M.² Rappa, G.³ Sen, S.⁴ Erba, E.⁵ D'Incalci, M.⁶

39
- 0014478592
- The locus of action of 1-b-D-arabinofuranosylcytosine in the cell cycle
- (1970) Cancer Res , vol.29 , pp. 687-694
- Karon, M.¹ Chirakawa, S.²

40
- 0031858217
- Preclinical cellular pharmacology of LY231514 (MTA): A comparison with methotrexate, LY309887 and raltitrexed for their effects on intracellular folate and nucleoside triphosphate pools in CCRF-CEM cells
- (1998) Br. J. Cancer , vol.78 , pp. 27-34
- Chen, V.J.¹ Bewley, J.R.² Andis, S.L.³ Schultz, R.M.⁴ Iversen, P.W.⁵ Shih, C.⁶ Mendelsohn, L.G.⁷ Seitz, D.E.⁸ Tonkinson, J.L.⁹

41
- 0025614367
- Biochemical interactions between methotrexate and 1-beta-D-arabinofuranosylcytosine in hematopoietic cells of children: A Pediatric Oncology Group study
- (1990) Cancer Chemother. Pharmacol , vol.27 , pp. 60-66
- Newman, E.M.¹ Villacorte, D.G.² Testi, A.M.³ Krance, R.A.⁴ Harris, M.B.⁵ Ravindranath, Y.⁶ Pinkel, D.⁷

42
- 0026482332
- Long term neuropsychologic sequence of childhood leukemia: Comparison of two CNS prophylactic regimens
- (1992) Int. J. Radiat. Oncol. Biol. Phys , vol.24 , pp. 49-53
- Giralt, J.¹ Ortega, J.J.² Oliwe, T.³ Verges, R.⁴ Forio, I.⁵ Salvador, L.⁶

43
- 0035886710
- Brief-duration high-intensity chemotherapy for patients with small noncleaved-cell lymphoma or FAB L3 acute lymphocytic leukemia: Results of cancer and leukemia group B study 9251
- (2001) J. Clin. Oncol , vol.19 , pp. 4014-4022
- Lee, E.J.¹ Petroni, G.R.² Schiffer, C.A.³ Freter, C.E.⁴ Johnson, J.L.⁵ Barcos, M.⁶ Frizzera, G.⁷ Bloomfield, C.D.⁸ Peterson, B.A.⁹

44
- 0021233114
- Cytosine arabinoside cerebrospinal fluid kinetics
- (1984) Clin. Pharmacol. Ther , vol.35 , pp. 826-830
- Zimm, S.¹ Collins, J.M.² Miser, J.³ Chatterji, D.⁴ Poplack, D.⁵

45
- 0024440649
- Variability in the disposition of intraventricular methotrexate: A proposal for rational dosing
- (1989) J. Clin. Oncol , vol.7 , pp. 1741-1747
- Strother, D.R.¹ Glynn-Barnhart, A.² Kovnar, E.³ Gregory, R.E.⁴ Murphy, S.B.⁵

46
- 0032711629
- A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors
- (1999) Clin. Cancer Res , vol.5 , pp. 3394-3402
- Glantz, M.J.¹ Jaeckle, K.A.² Chamberlain, M.C.³ Phuphanich, S.⁴ Recht, L.⁵ Swinnen, L.J.⁶ Maria, B.⁷ LaFollette, S.⁸ Schumann, G.B.⁹ Cole, B.F.¹⁰ Howell, S.B.¹¹

47
- 0027394689
- Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma
- (1993) N. Engl. J. Med , vol.328 , pp. 1002-1006
- Fisher, R.I.¹ Gaynor, E.R.² Dahlberg, S.³ Oken, M.M.⁴ Grogan, T.M.⁵ Mize, E.M.⁶ Glick, J.H.⁷ Coltman, C.A.⁸ Miller, T.P.⁹

48
- 0029983047
- Changes in red blood cell methotrexate pharmacology and their impact on outcome when cytarabine is infused with methotrexate in the treatment of acute lymphoblastic leukemia in children
- (1996) Clin. Cancer Res , vol.2 , pp. 331-337
- Graham, M.L.¹ Shuster, J.J.² Kamen, B.A.³ Land, V.J.⁴ Borowitz, M.J.⁵ Camitta, B.⁶ Cheo, D.L.⁷ Harrison, M.P.⁸ Leventhal, B.G.⁹ Pinkel, D.P.¹⁰ Pullen, D.J.¹¹ Steuber, P.¹² Whitehead, V.M.¹³

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