Poly(ADP-ribose) polymerase activity in the cat carotid body in hypoxia and hyperoxia

Journal of Physiology and Pharmacology

Volumn 53, Issue 3, 2002, Pages 491-496

  Strosznajder, R P ^a   Jesko, H ^a   Pokorski, M ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Carotid body; Hyperoxia; Hypoxia; Neural tissue; Poly(ADP ribose) polymerase; Reactive oxygen species

Indexed keywords

CELL DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; BRAIN STEM; CAROTID BODY CHEMORECEPTOR; CAT; CHEMOSENSITIVITY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; FEMALE; HYPEROXIA; HYPOXIA; IN VIVO STUDY; MALE; NERVOUS TISSUE; NONHUMAN; OXYGEN TENSION; STIMULATION; SUPERIOR CERVICAL GANGLION; TISSUE HOMOGENATE;

ANIMALS; ANOXIA; CAROTID BODY; CATS; FEMALE; HYPEROXIA; MALE; POLY(ADP-RIBOSE) POLYMERASES; REFERENCE VALUES;

EID: 0036739710     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Lahiri S, Rozanov C, Roy A, Storey B, Buerk DG. Regulation of oxygen sensing in peripheral arterial chemoreceptors. Inter J Biochem Cell Biol 2001; 33: 755-74.
2. Shirahata M, Sham JS. Roles of ion channels in carotid body chemotransmission of acute hypoxia. Jpn J Physiol 1999; 49: 213-228.
3. Summers BA, Overholt JL, Prabhakar NR. Augmentation of L-type calcium current by hypoxia in rabbit carotid body glomus cells: evidence for a PKC-sensitive pathway. J Neurophysiol 2000; 84: 1636-44.
4. Ozturk G, Mulholland CW, Hannigan BM. Vitamin C decreases intracellular calcium level in human lymphoid cells. J Physiol Pharmacol 2001; 52: 285-292.
5. 2-dependence of phospholipase C in the cat carotid body. Adv Exp Med Biol 1993; 337: 191-195.
6. Pokorski M, Sakagami H, Kondo H. Classical protein kinase C and its hypoxic stimulus-induced translocation in the cat and rat carotid body. Eur Respir J 2000; 16: 459-463.
7. Schabo C, Dawson VL. Role of poly(ADP-ribose) synthetase in inflammation and ischemia-reperfusion. Trends Pharmacol Sci 1998; 19: 287-298.
8. Thiemermann C, Bowes J, Myint FP, Vane JR. Inhibition of the activity of poly(ADP-ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle. Proc Natl Acad Sci 1997; 94: 679-683.
9. Nduka N, Skidmore CJ, Shall S. The enhancement of cytotoxicity of N-methyl-N-nitrosourea and gamma irradiation by inhibitors of poly(ADP-ribose) polymerase. Eur J Biochem 1980; 105: 525-533.
10. Berger NA. Oxidant-induced cytotoxicity: a challenge for metabolic modulation. Am J Respir Cell Mol Biol 1991; 4: 1-3.
11. Hess MI, Greenfield TD, Manson NH, Okabe E. The role of oxygen free radicals during the course of myocardial ischemia/reperfusion injury: an analysis and critique. In Oxygen Radicals in Pathophysiology of Heart Disease, PK Singal (ed). Boston, Kluwer Academic Publishers, 1988, pp. 111-122.
12. Pokorski M, Gonet B. Hypoxia depletes ascorbate in the cat carotid body. Respir Physiol 1997; 107: 213-218.
13. Cacciuttolo MA, Trinh L, Lumpkin JA, Rao G. Hyperoxia induces DNA damage in mammalian cells. Free Radic Biol Med 1993; 14: 267-276.
14. 2-mediated injury of preterm pneumocytes in vitro. Arch Biochem Biophys 1994; 313: 131-138.
15. Zhang J, Dawson VL, Dawson TM, Snyder SH. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 1994; 263: 687-689.
16. Homburg S, Visochek, Moran N et al. A fast signal-induced activation of poly(ADP-ribose) polymerase: a novel downstream target of phsopholipase C. J Cell Biol 2000: 150: 293-307.