Aberrant apoptosis in thyroid epithelial cells from goiter nodules

Journal of Clinical Endocrinology and Metabolism

Volumn 87, Issue 9, 2002, Pages 4264-4272

  Mezosi, Emese ^a   Yamazaki, Hiroko ^a   Bretz, James D ^a   Wang, Su He ^a   Arscott, Patricia L ^a   Utsugi, Saho ^a   Gauger, Paul G ^a   Thompson, Norman W ^a   Baker Jr , James R ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 18; CYTOKINE; FAS LIGAND; GAMMA INTERFERON; HLA DR5 ANTIGEN; INTERLEUKIN 1BETA; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ADULT; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; FLOW CYTOMETRY; GOITER; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MALE; NODULAR GOITER; PRIORITY JOURNAL; THYROID DISEASE;

ACETYLCYSTEINE; ANTIGENS, CD95; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL SURVIVAL; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; EPITHELIAL CELLS; GOITER, NODULAR; HUMANS; IMMUNOBLOTTING; INTERFERON-GAMMA, RECOMBINANT; KERATINS; MEMBRANE GLYCOPROTEINS; REFERENCE VALUES; THYROID GLAND; THYROIDECTOMY; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036738442     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-020111     Document Type: Article

References (43)

1. Derwahl M 1996 Editorial: TSH receptor and Gs-αmutations in the pathogenesis of toxic thyroid adenomas - a note of caution. J Clin Endocrinol Metab 81:2783-2785
2. Derwahl M 1996 Molecular aspects of the pathogenesis of nodular goiters, thyroid nodules and adenomas. Exp Clin Endocrinol Diabetes 104(Suppl 4): 32-35
3. Studer H, Derwahl M 1995 Mechanisms of nonneoplastic endocrine hyperplasia - a changing concept: a review focused on the thyroid gland. Endocr Rev 16:411-426
4. Bidey SP, Hill DJ, Eggo MC 1999 Growth factors and goitrogenesis. J Endocrinol 160:321-332
5. Gartner R, Veitenhansl M, Aktas J, Schopohl D 1996 Role of basic fibroblast growth factor in the pathogenesis of nodular goiter. Exp Clin Endocrinol Diabetes 104(Suppl 4):36-38
6. Maiorano E, Ambrosi A, Giorgino R, Fersini M, Pollice L, Ciampolillo A 1994 Insulin-like growth factor 1 (IGF-1) in multinodular goiters: a possible pathogenetic factor. Path Res Pract 190:1012-1016
7. Asmis LM, Kaempf J, Gruenigen CV, Kimura ET, Wagner HE, Studer H 1996 Acquired and naturally occurring resistance of thyroid follicular cells to the growth inhibitory action of transforming growth factor-β1 (TGF-β1). J Endocrinol 149:485-496
8. Vaux DL, Korsmeyer SJ 1999 Cell death in development. Cell 96:245-254
9. Siegel RM, Fleisher TA 1999 The role of Fas and related death receptors in autoimmune and other disease states. J Allerg Clin Immunol 103:729-738
10. Arscott PL, Baker Jr JR 1998 Apoptosis and thyroiditis. Clin Immunol Immunopathol 87:207-217
11. Bretz JD, Baker Jr JR 2001 Apoptosis and autoimmune thyroid disease: following a TRAIL to thyroid destruction? Clin Endocrinol 55:1-11
12. Mountz JD, Zhang HG, Hsu HC, Fleck M, Wu J, Al-Maini MH, Zhou T 1999 Apoptosis and cell death in the endocrine system. Rec Prog Horm Res 54:235-268
13. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima SI, Sameshima M, Hase A, Seto Y, Nagata S 1991 The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233-243
14. Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA, Goodwin RG 1995 Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3:673-682
15. Griffith TS, Brunner T, Fletcher SM, Green DR, Ferguson TA 1995 Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270:1189-1192
16. Lowin B, Hahne M, Mattmann C, Tschopp J 1994 Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 370:650-652
17. Borgerson KL, Bretz JD, Baker Jr JR 1999 The role of Fas-mediated apoptosis in thyroid autoimmune disease. Autoimmunity 30:251-264
18. Giordano CG, Stassi R, De Maria M, Todaro M, Richiusa P, Papoff G, Ruberti G, Bagnasco M, Testi R, Galluzzo A 1997 Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis. Science 275:960-963
19. Hammond LJ, Lowdell MW, Cerrano PG, Goode AW, Bottazzo GF, Mirakian R 1997 Analysis of apoptosis in relation to tissue destruction associated with Hashimoto's autoimmune thyroiditis. J Pathol 182:138-144
20. Tamura M, Kimura H, Koji T, Tominaga T, Ashizawa K, Kiriyama T, Yokoyama N, Yoshimura T, Eguchi K, Nakane PK, Nagataki S 1998 Role of apoptosis of thyrocytes in a rat model of goiter. A possible involvement of Fas system. Endocrinology 139:3646-3653
21. Griffith TS, Lynch DH 1998 TRAIL: a molecule with multiple receptors and control mechanisms. Curr Opin Immunol 10:559-563
22. Bonavida B, Ng CP, Jazirehi A, Schiller G, Mizutani Y 1999 Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics. Int J Oncol 15:793-802
23. Sedger LM, Shows DM, Blanton RA, Peschon JJ, Goodwin RG, Cosman D, Wiley SR 1999 IFN-γ mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression. J Immunol 163:920-926
24. Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM 1997 The receptor for the cytotoxic ligand TRAIL. Science 276:111-113
25. Walczak H, Krammer PH 2000 The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 256:58-66
26. Drexler HCA 1997 Activation of cell death program by inhibition of proteasome function. Proc Natl Acad SCi USA 94:855-860
27. Orlowski RZ 1999 The role of the ubiquitin-proteasome pathway in apoptosis. Cell Death Differ 6:303-313
28. Palombella VJ, Rando OJ, Goldberg AL, Maniatis T 1994 The ubiquitin-proteasome pathway is required for processing the NF-κ B1 precursor protein and the activation of NF-kappa B. Cell 78:773-785
29. Cui H, Matsui K, Omura S, Schauer SR, Matulka RA, Sonenshein GE 1997 Proteasome regulation of activation-induced T cell death. Proc Natl Acad Sci USA 94:7515-7520
30. Van Valen F, Fulda S, Truckenbrod B, Eckervogt V, Sonnemann J, Hillmann A, Rodl R, Hoffmann C, Winkelmann W, Schafer L, Dockhom-Dwomiczak B, Wessel T, Boos J, Debatin KM, Jurgens H 2000 Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL). Int J Cancer 88:252-259
31. Kim K 2001 Proteasome inhibitors sensitize human vascular smooth muscle cells to Fas (CD95)-mediated death. Biochem Biophys Res Comm 281:305-310
32. Lin KI, Baraban JM, Ratan RR 1998 Inhibition versus induction of apoptosis by proteasome inhibitors depends on concentration. Cell Death Differ 5:577-583
33. Tanimoto C, Hirakawa S, Kawasaki H, Hayakawa N, Ota Z 1995 Apoptosis in thyroid diseases: a histochemical study. Endocr J 42:193-201
34. Kikuchi S, Hiraide H, Tamakuma S, Yamamoto M 1997 Expression of wild-type p53 tumor suppressor gene and its possible involvement in the apoptosis of thyroid tumors. Surg Today 27:226-233
35. Moore D, Ohene-Fianko D, Garcia B, Chakrabarti S 1998 Apoptosis in thyroid neoplasms: relationship with p53 and bcl-2 expression. Histopathology 32:35-42
36. Sreelekha TT, Pradeep VM, Vijayalakshmi K, Belthazar A, Chellam VG, Nair B, Pillai MR 2000 In situ apoptosis in the thyroid. Thyroid 10:117-122
37. Arscott PL, Knapp J, Rymaszewski M, Bartron JL, Bretz JD, Thompson NW, Baker Jr JR 1997 Fas (APO-1, CD95)-mediated apoptosis in thyroid cells is regulated by a labile protein inhibitor. Endocrinology 138:5019-5027
38. Bretz JD, Rymaszewski M, Arscott PL, Myc A, Ain KB, Thompson NW, Baker Jr JR 1999 TRAIL death pathway expression and induction in thyroid follicular cells. J Biol Chem 274:23627-23632.
39. Bretz JD, Arscott PL, Myc A, Baker Jr JR 1999 Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells. J Biol Chem 274:25433-25438
40. Bretz JD, Mezosi E, Giordano TJ, Gauger PG, Thompson NW, Baker Jr JR 2002 Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cells. Cell Death Diff 9:274-286
41. Chinnaiyan AM, Prasad U, Shankar S, Hamstra DA, Shanaiah M, Chenevert TL, Ross BD, Rehemtulla A 2000 Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad SCi USA 97;1754-1759
42. Killinger Jr WA, Dorofi DB, Tinsley Jr EA, Keagy BA, Johnson Jr G 1992 Flow cytometric analysis of organ preservation-induced endothelial cell membrane damage. Ann Thorac Surg 53:472-476
43. Zhang XD, Nguyen T, Thomas WD, Sanders JE, Hersey P 2000 Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types. FEBS Lett 482:193-199