Chemotherapy targeting methylthioadenosine phosphorylase (MTAP) deficiency in adult T cell leukemia (ATL)

Leukemia

Volumn 16, Issue 9, 2002, Pages 1799-1807

  Harasawa, H ^a   Yamada, Y ^a   Kudoh, M ^b   Sugahara, K ^a   Soda, H ^a   Hirakata, Y ^a   Sasaki, H ^b   Ikeda, S ^d   Matsuo, T ^b   Tomonaga, M ^c   Nobori, T ^e   Kamihira, S ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b NAGASAKI UNIVERSITY HOSPITAL   (Japan)

^c NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Sasebo Shiritsu Sogo Hospital   (Japan)

^e MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ATL; HTLV 1; L alanosine; MTAP; Real time PCR

Indexed keywords

5' METHYLTHIOADENOSINE; 5' METHYLTHIOADENOSINE PHOSPHORYLASE; ALANOSINE; CONCANAVALIN A; DEOXYADENOSINE; FOLIC ACID ANTAGONIST; MESSENGER RNA; METHOTREXATE; PROTEIN SYNTHESIS INHIBITOR;

ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; CYTOTOXICITY; DIAGNOSTIC ACCURACY; DRUG SENSITIVITY; DRUG TARGETING; ENZYME SUBSTRATE; GENE DELETION; GENE EXPRESSION; GENE INACTIVATION; GENETIC ANALYSIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; QUANTITATIVE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T CELL LEUKEMIA;

EID: 0036738151     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402570     Document Type: Article

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